$99 Cheap Delta flights New York (LGA) to St. Louis (STL)

Scoring cheap one-way Delta Air Lines flights from LGA to STL from $99 on Expedia is a breeze --- just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly return fares from $197 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for cheap Delta Air Lines flights from LaGuardia Airport (LGA) to Lambert-St. Louis Intl. Airport (STL) one to three months before your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and itinerary, the ideal day to book a domestic flight is usually Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest Delta Air Lines flight from LGA to STL departs at 6:55AM UTC-5, arriving at 8:54AM UTC-6. If you prefer to set off later in the day, the last Delta Air Lines flight leaves LGA at 6:59PM UTC-5 and touches down at STL at 9:02PM UTC-6. Flying before noon is generally a good option as morning flights are less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Heading from LGA to STL with Delta Air Lines comes with a variety of perks, including an excellent in-flight experience and a rewarding loyalty program. Plus, when you book through Expedia, One Key™ members can collect OneKeyCash™* to use on select future travel purchases. That's on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.