$148 Cheap Delta flights Melbourne (MLB) to Knoxville (TYS)

View $148 flight on Tue, Sep 2, 2025Opens in a new window

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$148 Cheap Delta flights Melbourne (MLB) to Knoxville (TYS)

Prices were available within the past 7 days and start at $148 for one-way flights and $269 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Aug 20 - Tue, Aug 26
MLB
Melbourne
TYS
Knoxville
$269 Roundtrip, found 1 hour ago
$269
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Aug 20 from Melbourne to Knoxville, returning Tue, Aug 26, priced at $269 found 1 hour ago
Delta
Sat, Aug 16 - Tue, Aug 19
MLB
Melbourne
TYS
Knoxville
$274 Roundtrip, found 1 hour ago
$274
Roundtrip
found 1 hour ago
Select Delta flight, departing Sat, Aug 16 from Melbourne to Knoxville, returning Tue, Aug 19, priced at $274 found 1 hour ago
Delta
Sat, Aug 16 - Mon, Aug 18
MLB
Melbourne
TYS
Knoxville
$279 Roundtrip, found 1 hour ago
$279
Roundtrip
found 1 hour ago
Select Delta flight, departing Sat, Aug 16 from Melbourne to Knoxville, returning Mon, Aug 18, priced at $279 found 1 hour ago
Delta
Tue, Jan 6 - Wed, Jan 7
MLB
Melbourne
TYS
Knoxville
$295 Roundtrip, found 5 days ago
$295
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jan 6 from Melbourne to Knoxville, returning Wed, Jan 7, priced at $295 found 5 days ago
Delta
Sat, Nov 8 - Mon, Nov 17
MLB
Melbourne
TYS
Knoxville
$299 Roundtrip, found 13 hours ago
$299
Roundtrip
found 13 hours ago
Select Delta flight, departing Sat, Nov 8 from Melbourne to Knoxville, returning Mon, Nov 17, priced at $299 found 13 hours ago
Delta
Sun, Aug 10 - Sat, Aug 16
MLB
Melbourne
TYS
Knoxville
$304 Roundtrip, found 17 hours ago
$304
Roundtrip
found 17 hours ago
Select Delta flight, departing Sun, Aug 10 from Melbourne to Knoxville, returning Sat, Aug 16, priced at $304 found 17 hours ago
Flights from Melbourne (MLB) to Knoxville (TYS)
Origin airport
Orlando Melbourne Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta
Popular airline
Delta
Distance
567 mi

Frequently asked questions

How much is a Delta Air Lines flight from Orlando Melbourne Intl. Airport (MLB) to McGhee Tyson Airport (TYS)?
Finding cheap one-way Delta Air Lines flights from MLB to TYS from $148 on Expedia is a cinch — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $269 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from MLB to TYS with Delta Air Lines?
Delta Air Lines flights to Knoxville tend to be more affordable in the off-peak months of January and December. Whether you're searching for a round-trip or one-way ticket, you could land a better deal then.
What is the cheapest time to book flights from Orlando Melbourne Intl. Airport (MLB) to McGhee Tyson Airport (TYS) with Delta Air Lines?
Search for cheap Delta Air Lines flights from Orlando Melbourne Intl. Airport (MLB) to McGhee Tyson Airport (TYS) one to three months before your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the best day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.
Does Delta Air Lines fly nonstop from Orlando Melbourne Intl. Airport (MLB) to McGhee Tyson Airport (TYS)?
Enter your dates, hit search and use the "Nonstop" filter on Expedia to find any direct flights from MLB to TYS with Delta Air Lines or another airline.
What is the earliest Delta Air Lines flight from MLB to TYS?
Browse Delta Air Lines's earliest flights from MLB to TYS by using our "Early Morning" and "Morning" filters. Not only will you arrive at your destination sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports does Delta Air Lines fly into in Knoxville?
Delta Air Lines flights from Orlando Melbourne Intl. Airport (MLB) to Knoxville come in to McGhee Tyson Airport (TYS). This is the main entry point to this city.
Why fly with Delta Air Lines from MLB to TYS?
Delta Air Lines makes traveling from MLB to TYS more comfortable with a rewarding loyalty program and an excellent in-flight experience. You could even start earning points with Delta SkyMiles. Don't forget to join our free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future bookings.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
Can I change or cancel my Delta Air Lines flight from Orlando Melbourne Intl. Airport (MLB) to McGhee Tyson Airport (TYS)?
Changes are generally free within 24 hours of making your booking, but your airline may add a charge after that time. For further details about altering your reservation, go to your "Trips," select your flight and click on "Manage Booking." If you'd like the freedom to update your itinerary without additional costs, apply the "Changes included" or "No cancel fee" filter when planning your next adventure.
*Available to One Key members.