$234 Cheap Delta flights Houston (HOU) to Knoxville (TYS)

View $234 flight on Thu, Aug 14, 2025Opens in a new window

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$234 Cheap Delta flights Houston (HOU) to Knoxville (TYS)

Prices were available within the past 7 days and start at $234 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Oct 8 - Tue, Oct 14
HOU
Houston
TYS
Knoxville
$229 Roundtrip, just found
$229
Roundtrip
just found
Select Delta flight, departing Wed, Oct 8 from Houston to Knoxville, returning Tue, Oct 14, priced at $229 just found
Delta
Mon, Oct 6 - Thu, Oct 16
IAH
Houston
TYS
Knoxville
$229 Roundtrip, just found
$229
Roundtrip
just found
Select Delta flight, departing Mon, Oct 6 from Houston to Knoxville, returning Thu, Oct 16, priced at $229 just found
Delta
Tue, Sep 23 - Mon, Sep 29
HOU
Houston
TYS
Knoxville
$254 Roundtrip, found 11 hours ago
$254
Roundtrip
found 11 hours ago
Select Delta flight, departing Tue, Sep 23 from Houston to Knoxville, returning Mon, Sep 29, priced at $254 found 11 hours ago
Delta
Tue, Jul 22 - Mon, Jul 28
IAH
Houston
TYS
Knoxville
$264 Roundtrip, found 3 hours ago
$264
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Jul 22 from Houston to Knoxville, returning Mon, Jul 28, priced at $264 found 3 hours ago
Delta
Sun, Oct 5 - Thu, Oct 16
IAH
Houston
TYS
Knoxville
$274 Roundtrip, just found
$274
Roundtrip
just found
Select Delta flight, departing Sun, Oct 5 from Houston to Knoxville, returning Thu, Oct 16, priced at $274 just found
Delta
Sun, Aug 31 - Sat, Sep 20
HOU
Houston
TYS
Knoxville
$279 Roundtrip, found 17 hours ago
$279
Roundtrip
found 17 hours ago
Select Delta flight, departing Sun, Aug 31 from Houston to Knoxville, returning Sat, Sep 20, priced at $279 found 17 hours ago
Flights from Houston (IAH) to Knoxville (TYS)
Origin airport
George Bush Intercontinental
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta
Popular airline
Delta
Distance
770 mi
Average flight time
2 hours 7 mins

Frequently asked questions

How much is a Delta Air Lines flight from William P. Hobby Airport (HOU) to McGhee Tyson Airport (TYS)?
Make use of the "Price (lowest to highest)" filter on Expedia to look for cheap Delta Air Lines return flights from $229 from HOU to TYS. Affordable one-way options from $234 are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from HOU to TYS with Delta Air Lines?
Look for one-way or return flights to Knoxville in January or December. You could find cheaper fares with Delta Air Lines during these off-peak times.
What is the cheapest time to book flights from William P. Hobby Airport (HOU) to McGhee Tyson Airport (TYS) with Delta Air Lines?
Look for affordable Delta Air Lines flights from William P. Hobby Airport (HOU) to McGhee Tyson Airport (TYS) one to three months ahead of your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the best day to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.
Does Delta Air Lines fly nonstop from William P. Hobby Airport (HOU) to McGhee Tyson Airport (TYS)?
Simply enter your dates, press search and select the "Nonstop" filter on Expedia to browse any direct flights from HOU to TYS with Delta Air Lines or other airlines.
What is the earliest Delta Air Lines flight from HOU to TYS?
To find the earliest departure from HOU to TYS with Delta Air Lines, filter your search by "Morning" and "Early Morning." Choosing an early flight generally means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports does Delta Air Lines fly into in Knoxville?
McGhee Tyson Airport (TYS) is the primary Knoxville hub for Delta Air Lines flights from William P. Hobby Airport (HOU).
Why fly with Delta Air Lines from HOU to TYS?
With a rewarding loyalty program and an excellent in-flight experience, Delta Air Lines is the leading choice for many travelers flying from HOU to TYS. Also, if you're a Delta SkyMiles and One Key™ member booking through Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can be spent on future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
Can I change or cancel my Delta Air Lines flight from William P. Hobby Airport (HOU) to McGhee Tyson Airport (TYS)?
Typically, you can cancel or reschedule your flight, although there may be additional fees if you made your booking more than 24 hours ago. Need flexible options? Use Expedia's "No cancel fee" and "Changes included" filters to find flights that won't charge extra if you have to adjust your plans. To update your booking, visit "Trips," select your flight and click on "Manage Booking" for more details.

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