$174 Cheap Frontier Airlines flights New Orleans (MSY) to Knoxville (TYS)

View $174 flight on Sun, Oct 12, 2025Opens in a new window

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$174 Cheap Frontier Airlines flights New Orleans (MSY) to Knoxville (TYS)

Prices were available within the past 7 days and start at $174 for one-way flights and $316 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sun, Oct 19 - Thu, Oct 23
MSY
New Orleans
TYS
Knoxville
$316 Roundtrip, found 2 days ago
$316
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Oct 19 from New Orleans to Knoxville, returning Thu, Oct 23, priced at $316 found 2 days ago
Flights from New Orleans (MSY) to Knoxville (TYS)
Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, United
Popular airline
Delta
Distance
541 mi

Frequently asked questions

How much is a Frontier Airlines flight from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS)?
Landing cheap one-way Frontier Airlines flights from MSY to TYS from $174 on Expedia is a breeze --- just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $316 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from MSY to TYS with Frontier Airlines?
Browse for one-way or round-trip flights to Knoxville in January or December. You could find lower fares with Frontier Airlines during these off-peak travel months.
What is the cheapest time to book flights from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS) with Frontier Airlines?
For cheap Frontier Airlines fares from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS), start searching one to three months before your planned departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect the overall price. Sunday is usually the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by choosing to book on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.
Does Frontier Airlines fly nonstop from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS)?
To see if there's a direct route from MSY to TYS with Frontier Airlines or another carrier, check the "Nonstop" filter when looking for tickets.
What is the earliest Frontier Airlines flight from MSY to TYS?
Find Frontier Airlines's earliest flights from MSY to TYS by using our "Morning" and "Early Morning" filters. Not only will you arrive sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports does Frontier Airlines fly into in Knoxville?
Jump on a Frontier Airlines flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Knoxville, and you'll most likely touch down at McGhee Tyson Airport (TYS). This is the airline's primary hub in this destination.
Why fly with Frontier Airlines from MSY to TYS?
Offering a rewarding loyalty program, Frontier Airlines is a popular choice for many travelers departing from MSY to TYS. Plus, if you're a Frontier Miles and One Key™ member booking through Expedia, you can earn OneKeyCash™* on eligible flights along with your airline miles.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
Can I change or cancel my Frontier Airlines flight from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS)?
Changes are often free within 24 hours of making a booking, but your airline may charge a fee after that time. For more details about altering your flights, check out your "Trips," select your flight and click on "Manage Booking." If you want the flexibility to adjust your plans without extra charges, check the "Changes included" or "No cancel fee" filter when planning your trip.

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*Available to One Key members.