$148 Cheap Flights from Buffalo (BUF) to Key West (EYW)

View $148 flight on Sat, Oct 25, 2025Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW)

Cheap Flights from Buffalo to Key West (BUF-EYW)

Prices were available within the past 7 days and start at $148 for one-way flights and $269 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Oct 29 - Fri, Nov 7
BUF
Buffalo
EYW
Key West
$269 Roundtrip, just found
$269
Roundtrip
just found
Select Delta flight, departing Wed, Oct 29 from Buffalo to Key West, returning Fri, Nov 7, priced at $269 just found
Delta
Tue, Nov 4 - Wed, Nov 12
BUF
Buffalo
EYW
Key West
$274 Roundtrip, just found
$274
Roundtrip
just found
Select Delta flight, departing Tue, Nov 4 from Buffalo to Key West, returning Wed, Nov 12, priced at $274 just found
JetBlue Airways
Thu, Oct 16 - Thu, Oct 23
BUF
Buffalo
EYW
Key West
$276 Roundtrip, found 2 hours ago
$276
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Thu, Oct 16 from Buffalo to Key West, returning Thu, Oct 23, priced at $276 found 2 hours ago
Delta
Wed, Oct 15 - Mon, Oct 20
BUF
Buffalo
EYW
Key West
$279 Roundtrip, found 2 hours ago
$279
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Oct 15 from Buffalo to Key West, returning Mon, Oct 20, priced at $279 found 2 hours ago
American Airlines
Fri, Oct 31 - Sat, Nov 8
BUF
Buffalo
EYW
Key West
$283 Roundtrip, found 2 hours ago
$283
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Oct 31 from Buffalo to Key West, returning Sat, Nov 8, priced at $283 found 2 hours ago
American Airlines
Sat, Jan 17 - Sat, Jan 24
BUF
Buffalo
EYW
Key West
$288 Roundtrip, found 8 hours ago
$288
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Buffalo to Key West, returning Sat, Jan 24, priced at $288 found 8 hours ago
American Airlines
Sat, Jan 17 - Sat, Jan 24
BUF
Buffalo
EYW
Key West
$293 Roundtrip, found 8 hours ago
$293
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Buffalo to Key West, returning Sat, Jan 24, priced at $293 found 8 hours ago
Delta
Wed, Oct 1 - Tue, Oct 7
BUF
Buffalo
EYW
Key West
$299 Roundtrip, just found
$299
Roundtrip
just found
Select Delta flight, departing Wed, Oct 1 from Buffalo to Key West, returning Tue, Oct 7, priced at $299 just found
JetBlue Airways
Wed, Oct 15 - Thu, Oct 23
BUF
Buffalo
EYW
Key West
$303 Roundtrip, found 4 days ago
$303
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Wed, Oct 15 from Buffalo to Key West, returning Thu, Oct 23, priced at $303 found 4 days ago
United
Thu, May 7 - Tue, May 12
BUF
Buffalo
EYW
Key West
$314 Roundtrip, found 4 days ago
$314
Roundtrip
found 4 days ago
Select United flight, departing Thu, May 7 from Buffalo to Key West, returning Tue, May 12, priced at $314 found 4 days ago

Find the cheapest month to fly from Buffalo (BUF) to Key West (EYW)

May is typically the cheapest month to fly

From $212 - $557 per traveler.

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW) cost?
Lock in a cheap one-way flight from $148 or cheap return flight from $269 from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW)?
October is the least expensive month to fly from BUF to EYW. Traveling outside of peak seasons is often the key to landing a great deal.
What is the cheapest airline that flies from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest BUF to EYW flight.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW)?
There aren't any daily direct flights departing from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from BUF to EYW?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW)?
Select a flight from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW) that takes off before 3 PM to reduce the risk of delays and cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW) last-minute?
Booking your plane ticket from BUF to EYW shortly before your journey is usually more expensive. But if you're flexible with your travel times and dates, you could score a cheap last-minute fare.
Is it cheaper to book a BUF to EYW flight and hotel package?
You'll generally save money by booking a BUF to EYW flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've selected your preferred flights and accommodations, consider adding extras including tours, activities and car rentals.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Key West Intl. Airport (EYW)?
Usually, it's possible to reschedule or cancel your BUF to EYW flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, United
Roundtrip price
$268
Distance
1281 mi

Book with confidence

Book with confidence

Buffalo to Key West Flights

The cheapest times to fly from Buffalo to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Key West are during the month of October. You can find some of the cheapest flights from Buffalo to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Key West

Sunday is one of the best days to book for cheap flights from Buffalo to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $148 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buffalo to Key West Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.