
Popular airlines from Charleston Intl. Airport (CHS) to Columbia, MO (COU-Columbia Regional)
- American Airlines
American Airlines
- United
United
- Southwest Airlines
Southwest Airlines
- Delta
Delta
- Frontier Airlines
Frontier Airlines
- JetBlue Airways
JetBlue Airways
- Alaska Airlines
Alaska Airlines
- Plan, book, fly with confidence
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Cheap Flights from Charleston to Columbia (CHS-COU)
Prices were available within the past 7 days and start at $364 for one-way flights and $470 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Alternative airports near Columbia
Prices were available within the past 7 days. Prices and availability are subject to change.
Origin airport | Charleston Intl. |
Destination airport | Columbia Regional |
Roundtrip price | $469 |
Distance | 794 mi |
Charleston to Columbia Flights
The cheapest times to fly from Charleston to Columbia
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to Columbia are during the month of September. You can find some of the cheapest flights from Charleston to Columbia with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Charleston to Columbia
Sunday is one of the best days to book for cheap flights from Charleston to Columbia: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Charleston to Columbia
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to Columbia in 2025. You can also book with separate airlines for your outbound and return journeys, from $364 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to Columbia flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to Columbia airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Top Routes from Charleston
- Charleston to Chicago (CHS - ORD)
- Charleston to Newark Liberty Intl. Airport (CHS - EWR)
- Charleston to Los Angeles (CHS - LAX)
- Charleston to Miami (CHS - MIA)
- Charleston to Tampa (CHS - TPA)
- Charleston to New York (CHS - LGA)
- Charleston to Fort Lauderdale (CHS - FLL)
- Charleston to Boston (CHS - BOS)
- Charleston to Denver (CHS - DEN)
- Charleston to New York (CHS - JFK)
- Charleston to Seattle (CHS - SEA)
- Charleston to Houston (CHS - IAH)
Top Routes to Columbia
- Chicago to Columbia (ORD - COU)
- San Luis Obispo to Columbia (SBP - COU)
- Newark Liberty Intl. Airport to Columbia (EWR - COU)
- Baton Rouge to Columbia (BTR - COU)
- Los Angeles to Columbia (LAX - COU)
- Birmingham to Columbia (BHM - COU)
- Boston to Columbia (BOS - COU)
- New York to Columbia (LGA - COU)
- Portland to Columbia (PWM - COU)
- Hartford to Columbia (BDL - COU)
- Denver to Columbia (DEN - COU)
- New York to Columbia (JFK - COU)
Top Routes from Charleston
- American Airlines Charleston to Chicago
- JetBlue Airways Charleston to Los Angeles
- American Airlines Charleston to Miami
- American Airlines Charleston to New York
- JetBlue Airways Charleston to Fort Lauderdale
- JetBlue Airways Charleston to Boston
- American Airlines Charleston to Denver
- JetBlue Airways Charleston to New York
- Alaska Airlines Charleston to Seattle
- American Airlines Charleston to Houston
Top Routes to Columbia
- American Airlines San Luis Obispo to Columbia
- American Airlines Newark Liberty Intl. Airport to Columbia
- American Airlines Los Angeles to Columbia
- American Airlines New York to Columbia
- American Airlines Hartford to Columbia
- American Airlines Denver to Columbia
- American Airlines New York to Columbia
- American Airlines Seattle to Columbia
- American Airlines Dallas to Columbia
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Nearby Airports
- Hilton Head Island Airport (HHH)
- Myrtle Beach Intl. Airport (MYR)
- Savannah - Hilton Head Intl. Airport (SAV)
- Florence Regional Airport (FLO)
- Columbia Metropolitan Airport (CAE)
- Grand Strand Airport (CRE)
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- Golden Isles Airport (BQK)
- Wilmington Intl. Airport (ILM)
- Fayetteville Regional Airport (FAY)
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