$310 Cheap Flights from Charlotte (CLT) to La Crosse (LSE)

View $310 flight on Sat, Oct 11, 2025Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to La Crosse, WI (LSE-La Crosse Municipal)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Charlotte to La Crosse (CLT-LSE)

Prices were available within the past 7 days and start at $310 for one-way flights and $432 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Oct 7 - Tue, Oct 14
CLT
Charlotte
LSE
La Crosse
$432 Roundtrip, found 3 days ago
$432
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Oct 7 from Charlotte to La Crosse, returning Tue, Oct 14, priced at $432 found 3 days ago
American Airlines
Sat, Jan 10 - Sun, Jan 11
CLT
Charlotte
LSE
La Crosse
$451 Roundtrip, found 6 hours ago
$451
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Jan 10 from Charlotte to La Crosse, returning Sun, Jan 11, priced at $451 found 6 hours ago
American Airlines
Sat, Jan 10 - Sun, Jan 11
CLT
Charlotte
LSE
La Crosse
$457 Roundtrip, found 6 hours ago
$457
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Jan 10 from Charlotte to La Crosse, returning Sun, Jan 11, priced at $457 found 6 hours ago
American Airlines
Fri, Oct 24 - Mon, Oct 27
CLT
Charlotte
LSE
La Crosse
$484 Roundtrip, found 6 days ago
$484
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Oct 24 from Charlotte to La Crosse, returning Mon, Oct 27, priced at $484 found 6 days ago
American Airlines
Wed, Jan 7 - Sat, Jan 10
CLT
Charlotte
LSE
La Crosse
$488 Roundtrip, found 6 hours ago
$488
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Jan 7 from Charlotte to La Crosse, returning Sat, Jan 10, priced at $488 found 6 hours ago
American Airlines
Tue, Oct 21 - Sat, Nov 1
CLT
Charlotte
LSE
La Crosse
$495 Roundtrip, found 2 hours ago
$495
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Oct 21 from Charlotte to La Crosse, returning Sat, Nov 1, priced at $495 found 2 hours ago
American Airlines
Fri, Oct 24 - Mon, Oct 27
CLT
Charlotte
LSE
La Crosse
$501 Roundtrip, found 6 days ago
$501
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Oct 24 from Charlotte to La Crosse, returning Mon, Oct 27, priced at $501 found 6 days ago
American Airlines
Tue, Oct 21 - Sat, Oct 25
CLT
Charlotte
LSE
La Crosse
$502 Roundtrip, found 2 hours ago
$502
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Oct 21 from Charlotte to La Crosse, returning Sat, Oct 25, priced at $502 found 2 hours ago
American Airlines
Wed, Oct 8 - Sat, Oct 11
CLT
Charlotte
LSE
La Crosse
$508 Roundtrip, found 3 days ago
$508
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 8 from Charlotte to La Crosse, returning Sat, Oct 11, priced at $508 found 3 days ago
American Airlines
Wed, Oct 8 - Sat, Oct 25
CLT
Charlotte
LSE
La Crosse
$513 Roundtrip, found 6 days ago
$513
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Oct 8 from Charlotte to La Crosse, returning Sat, Oct 25, priced at $513 found 6 days ago

Alternative airports near La Crosse

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to La Crosse Municipal LSE. Cheapest and Closest option available. Average driving time to city center is 12 minutes. Flights from $495
LSE
La Crosse Municipal
CheapestClosest
Average driving time to city center12 min
Flights from $495

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE) cost?
Grab a cheap one-way flight from $310 or cheap return flight from $432 from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE)?
October is the cheapest month to fly from CLT to LSE. Avoiding peak travel times is often the key to finding better deals on flights.
What is the cheapest airline that flies from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from CLT to LSE. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE)?
You'll have to catch a flight with a layover when traveling from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from CLT to LSE?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE)?
Book a flight from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE) last-minute?
Last-minute fares from CLT to LSE are typically more expensive. To lock in the best rates, start looking for flights early. That said, if your travel plans are flexible, it's possible to land a cheap ticket right before your journey.
Is it cheaper to book a CLT to LSE flight and hotel package?
You'll typically save money by securing a CLT to LSE flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After selecting your ideal accommodations and flights, you can add extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to La Crosse Municipal Airport (LSE)?
In most cases, you're able to reschedule or cancel your CLT to LSE flight. However, additional fees may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you need further details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Charlotte-Douglas Intl.
Destination airport
La Crosse Municipal
Airlines serving
American Airlines
Roundtrip price
$432
Distance
810 mi

Book with confidence

Book with confidence

Charlotte to La Crosse Flights

The cheapest times to fly from Charlotte to La Crosse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to La Crosse are during the month of October. You can find some of the cheapest flights from Charlotte to La Crosse with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charlotte to La Crosse

Sunday is one of the best days to book for cheap flights from Charlotte to La Crosse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charlotte to La Crosse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to La Crosse in 2025. You can also book with separate airlines for your outbound and return journeys, from $310 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to La Crosse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to La Crosse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charlotte to La Crosse Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.