$299 Cheap Flights from Casper (CPR) to Knoxville (TYS)

View $299 flight on Sun, Jan 11, 2026Opens in a new window

Popular airlines from Casper, WY (CPR-Natrona County Intl.) to McGhee Tyson Airport (TYS)

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Cheap Flights from Casper to Knoxville (CPR-TYS)

Prices were available within the past 7 days and start at $299 for one-way flights and $278 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Jan 27 - Sat, Jan 31
CPR
Casper
TYS
Knoxville
$278 Roundtrip, found 4 days ago
$278
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jan 27 from Casper to Knoxville, returning Sat, Jan 31, priced at $278 found 4 days ago
United
Tue, Jan 27 - Sat, Jan 31
CPR
Casper
TYS
Knoxville
$284 Roundtrip, found 4 days ago
$284
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jan 27 from Casper to Knoxville, returning Sat, Jan 31, priced at $284 found 4 days ago
United
Tue, Jan 27 - Sat, Jan 31
CPR
Casper
TYS
Knoxville
$302 Roundtrip, found 4 days ago
$302
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jan 27 from Casper to Knoxville, returning Sat, Jan 31, priced at $302 found 4 days ago
United
Tue, Jan 6 - Mon, Jan 12
CPR
Casper
TYS
Knoxville
$303 Roundtrip, found 3 days ago
$303
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jan 6 from Casper to Knoxville, returning Mon, Jan 12, priced at $303 found 3 days ago
United
Tue, Jan 6 - Mon, Jan 12
CPR
Casper
TYS
Knoxville
$309 Roundtrip, found 3 days ago
$309
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jan 6 from Casper to Knoxville, returning Mon, Jan 12, priced at $309 found 3 days ago
United
Tue, Jan 27 - Sat, Jan 31
CPR
Casper
TYS
Knoxville
$343 Roundtrip, found 4 days ago
$343
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jan 27 from Casper to Knoxville, returning Sat, Jan 31, priced at $343 found 4 days ago
United
Tue, Jan 27 - Sat, Jan 31
CPR
Casper
TYS
Knoxville
$348 Roundtrip, found 4 days ago
$348
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jan 27 from Casper to Knoxville, returning Sat, Jan 31, priced at $348 found 4 days ago
United
Tue, Jan 27 - Sat, Jan 31
CPR
Casper
TYS
Knoxville
$354 Roundtrip, found 4 days ago
$354
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jan 27 from Casper to Knoxville, returning Sat, Jan 31, priced at $354 found 4 days ago
United
Tue, Mar 10 - Tue, Mar 17
CPR
Casper
TYS
Knoxville
$358 Roundtrip, found 1 day ago
$358
Roundtrip
found 1 day ago
Select United flight, departing Tue, Mar 10 from Casper to Knoxville, returning Tue, Mar 17, priced at $358 found 1 day ago
United
Tue, Jan 6 - Mon, Jan 12
CPR
Casper
TYS
Knoxville
$361 Roundtrip, found 3 days ago
$361
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jan 6 from Casper to Knoxville, returning Mon, Jan 12, priced at $361 found 3 days ago

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $389
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $389

Frequently asked questions

How much does a flight from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS) cost?
Grab a cheap one-way flight from $299 or cheap return flight from $278 from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS)?
The cheapest month to fly from CPR to TYS is January, when there's less demand. Off-peak months are usually when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from CPR to TYS. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS)?
Direct flights from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CPR to TYS?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS)?
Book a flight from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS) that leaves before 3 PM to reduce the risk of cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS) last-minute?
Booking your plane ticket from CPR to TYS shortly before your trip is typically more expensive. But if you're flexible with your schedule, you could bag a cheap last-minute fare.
Is it cheaper to book a CPR to TYS flight and hotel package?
Securing a CPR to TYS flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of accommodations and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Natrona County Intl. Airport (CPR) to McGhee Tyson Airport (TYS)?
If you reserved your CPR to TYS flight within the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

Travel information

Origin airport
Natrona County Intl.
Destination airport
McGhee Tyson
Airlines serving
United
Roundtrip price
$278
Distance
1291 mi

Book with confidence

Casper to Knoxville Flights

The cheapest times to fly from Casper to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Casper to Knoxville are during the month of January. You can find some of the cheapest flights from Casper to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Casper to Knoxville

Sunday is one of the best days to book for cheap flights from Casper to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Casper to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Casper to Knoxville in 2026. You can also book with separate airlines for your outbound and return journeys, from $299 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Casper to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Casper to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Casper to Knoxville Flights

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*Available to One Key members.