$119 Cheap Flights from Cusco (CUZ) to Santiago (SCL)

View $119 flight on Fri, Nov 21, 2025Opens in a new window

Popular airlines from Alejandro Velasco Astete Intl. Airport (CUZ) to Santiago Intl. Airport (SCL)

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Cheap Flights from Cusco to Santiago (CUZ-SCL)

Prices were available within the past 7 days and start at $119 for one-way flights and $253 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY AIRLINE
Thu, Aug 28 - Mon, Sep 1
CUZ
Cusco
SCL
Santiago
$253 Roundtrip, found 2 days ago
$253
Roundtrip
found 2 days ago
Select SKY AIRLINE flight, departing Thu, Aug 28 from Cusco to Santiago, returning Mon, Sep 1, priced at $253 found 2 days ago
LATAM Airlines Group
Wed, Nov 19 - Fri, Dec 5
CUZ
Cusco
SCL
Santiago
$263 Roundtrip, found 3 days ago
$263
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, Nov 19 from Cusco to Santiago, returning Fri, Dec 5, priced at $263 found 3 days ago
SKY AIRLINE
Thu, Aug 28 - Mon, Sep 1
CUZ
Cusco
SCL
Santiago
$267 Roundtrip, found 2 days ago
$267
Roundtrip
found 2 days ago
Select SKY AIRLINE flight, departing Thu, Aug 28 from Cusco to Santiago, returning Mon, Sep 1, priced at $267 found 2 days ago
SKY AIRLINE
Fri, Aug 29 - Tue, Sep 2
CUZ
Cusco
SCL
Santiago
$269 Roundtrip, found 2 days ago
$269
Roundtrip
found 2 days ago
Select SKY AIRLINE flight, departing Fri, Aug 29 from Cusco to Santiago, returning Tue, Sep 2, priced at $269 found 2 days ago
SKY AIRLINE
Fri, Aug 29 - Tue, Sep 2
CUZ
Cusco
SCL
Santiago
$272 Roundtrip, found 2 days ago
$272
Roundtrip
found 2 days ago
Select SKY AIRLINE flight, departing Fri, Aug 29 from Cusco to Santiago, returning Tue, Sep 2, priced at $272 found 2 days ago
SKY AIRLINE
Tue, Sep 2 - Tue, Sep 9
CUZ
Cusco
SCL
Santiago
$274 Roundtrip, found 2 days ago
$274
Roundtrip
found 2 days ago
Select SKY AIRLINE flight, departing Tue, Sep 2 from Cusco to Santiago, returning Tue, Sep 9, priced at $274 found 2 days ago
SKY AIRLINE
Fri, Oct 17 - Tue, Oct 28
CUZ
Cusco
SCL
Santiago
$276 Roundtrip, found 4 days ago
$276
Roundtrip
found 4 days ago
Select SKY AIRLINE flight, departing Fri, Oct 17 from Cusco to Santiago, returning Tue, Oct 28, priced at $276 found 4 days ago
LATAM Airlines Group
Fri, Aug 22 - Thu, Aug 28
CUZ
Cusco
SCL
Santiago
$280 Roundtrip, found 3 days ago
$280
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Fri, Aug 22 from Cusco to Santiago, returning Thu, Aug 28, priced at $280 found 3 days ago
SKY AIRLINE
Thu, Aug 28 - Mon, Sep 1
CUZ
Cusco
SCL
Santiago
$281 Roundtrip, found 2 days ago
$281
Roundtrip
found 2 days ago
Select SKY AIRLINE flight, departing Thu, Aug 28 from Cusco to Santiago, returning Mon, Sep 1, priced at $281 found 2 days ago
Jetsmart SPA
Fri, Aug 8 - Fri, Aug 22
CUZ
Cusco
SCL
Santiago
$311 Roundtrip, found 5 days ago
$311
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Fri, Aug 8 from Cusco to Santiago, returning Fri, Aug 22, priced at $311 found 5 days ago

Find the cheapest month to fly from Cusco (CUZ) to Santiago (SCL)

November is typically the cheapest month to fly

From $217 - $437 per traveler.

Graph displaying average flight prices per month

Flights from Cusco (CUZ) to Santiago (SCL)
Origin airport
Alejandro Velasco Astete Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
LATAM Airlines Group, SKY AIRLINE
Roundtrip price
$252
Distance
1373 mi
Average flight time
2 hours 20 mins

Cusco to Santiago Flights

The cheapest times to fly from Cusco to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cusco to Santiago are during the month of August. You can find some of the cheapest flights from Cusco to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cusco to Santiago

Sunday is one of the best days to book for cheap flights from Cusco to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cusco to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cusco to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $119 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cusco to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cusco to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL) cost?
Snag cheap return fares starting from $355 from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a LATAM Airlines Group flight leaving CUZ on August 1 2025 and touching down at SCL. The price was last updated on July 20 2025 and has not changed since.
What is the cheapest month to fly from CUZ to SCL?
The cheapest flights from CUZ to SCL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL)?
Take a direct flight with LATAM Airlines and fly straight from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL).
What is the cheapest airline that flies from CUZ to SCL?
Currently, the cheapest carrier operating one-way flights from CUZ to SCL is LATAM Airlines Group. You can take off on this route from $179. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from CUZ on October 8 2025. Prices were last updated on July 20 2025 and have not changed since.
How many flights per day from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL)?
On average, there is just 1 direct flight operating from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL) every day. If this doesn't work for you, think about flights with layovers. Just customize your search on Expedia to include one or more stops to find a better alternative.
What are the most popular departure times for flights from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL)?
Flights between CUZ and SCL are their busiest at 9 AM. If you're after a quieter trip and potentially cheaper fares, look for a departure that's outside typical rush times.
What day of the week has the most flights from CUZ to SCL?
Jet off on a Friday if you're looking for the best choice of flights from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL).
What is the earliest flight from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL)?
Alejandro Velasco Astete Intl. Airport (CUZ)'s earliest flight to Arturo Merino Benitez Airport (SCL) departs at approximately 9:10AM UTC-5. With a travel duration of 3h 20m, you'll touch down at around 2:30PM UTC-3.
How long does it take to fly from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL)?
It usually takes 3 hours and 20 minutes to cover the 1,400 mi from CUZ to SCL.
What airline has the least delays from CUZ to SCL?
With 90% of flights generally landing on schedule, LATAM Airlines has the best on-time performance for nonstop flights from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL). To check your flight status and get notified about any changes, use the Expedia App.
What is the best time to fly from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL)?
To avoid possible delays on the Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Santiago from Alejandro Velasco Astete Intl. Airport (CUZ)?
Arturo Merino Benitez Airport (SCL) is the only airport in Santiago with direct flights from Alejandro Velasco Astete Intl. Airport (CUZ). Explore your options and discover cheap fares on Expedia.
Is it cheaper to buy a plane ticket from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL) last-minute?
Booking your ticket from CUZ to SCL just before your getaway is generally more expensive. However, if you're flexible with your travel times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a CUZ to SCL flight and hotel package?
You'll generally save money by securing a CUZ to SCL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After selecting your ideal flights and accommodations, consider adding extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL)?
Typically, you can cancel or reschedule your CUZ to SCL flight. However, there may be additional fees, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you want further information, head to our Customer Service portal.

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