$146 Cheap Flights from Des Moines (DSM) to Amarillo (AMA)

View $146 flight on Tue, Feb 10, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Amarillo, TX (AMA-Rick Husband Amarillo Intl.)

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Cheap Flights from Des Moines to Amarillo (DSM-AMA)

Prices were available within the past 7 days and start at $146 for one-way flights and $297 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jan 13 - Wed, Jan 14
DSM
Des Moines
AMA
Amarillo
$297 Roundtrip, found 5 days ago
$297
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 13 from Des Moines to Amarillo, returning Wed, Jan 14, priced at $297 found 5 days ago
United
Tue, Jan 13 - Wed, Jan 14
DSM
Des Moines
AMA
Amarillo
$297 Roundtrip, found 5 days ago
$297
Roundtrip
found 5 days ago
Select United flight, departing Tue, Jan 13 from Des Moines to Amarillo, returning Wed, Jan 14, priced at $297 found 5 days ago
Southwest Airlines
Tue, Jan 13 - Wed, Jan 14
DSM
Des Moines
AMA
Amarillo
$307 Roundtrip, found 5 days ago
$307
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Jan 13 from Des Moines to Amarillo, returning Wed, Jan 14, priced at $307 found 5 days ago
American Airlines
Thu, Jan 8 - Tue, Jan 13
DSM
Des Moines
AMA
Amarillo
$311 Roundtrip, found 19 hours ago
$311
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Jan 8 from Des Moines to Amarillo, returning Tue, Jan 13, priced at $311 found 19 hours ago
Southwest Airlines
Tue, Jan 13 - Wed, Jan 14
DSM
Des Moines
AMA
Amarillo
$312 Roundtrip, found 5 days ago
$312
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Jan 13 from Des Moines to Amarillo, returning Wed, Jan 14, priced at $312 found 5 days ago
American Airlines
Thu, Jan 8 - Tue, Jan 13
DSM
Des Moines
AMA
Amarillo
$316 Roundtrip, found 19 hours ago
$316
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Jan 8 from Des Moines to Amarillo, returning Tue, Jan 13, priced at $316 found 19 hours ago
Southwest Airlines
Tue, Jan 13 - Wed, Jan 14
DSM
Des Moines
AMA
Amarillo
$318 Roundtrip, found 5 days ago
$318
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Jan 13 from Des Moines to Amarillo, returning Wed, Jan 14, priced at $318 found 5 days ago
American Airlines
Thu, Jan 8 - Mon, Jan 12
DSM
Des Moines
AMA
Amarillo
$321 Roundtrip, found 5 days ago
$321
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Jan 8 from Des Moines to Amarillo, returning Mon, Jan 12, priced at $321 found 5 days ago
Southwest Airlines
Thu, Jan 8 - Tue, Jan 13
DSM
Des Moines
AMA
Amarillo
$321 Roundtrip, found 19 hours ago
$321
Roundtrip
found 19 hours ago
Select Southwest Airlines flight, departing Thu, Jan 8 from Des Moines to Amarillo, returning Tue, Jan 13, priced at $321 found 19 hours ago
American Airlines
Thu, Jan 1 - Tue, Jan 20
DSM
Des Moines
AMA
Amarillo
$325 Roundtrip, found 2 days ago
$325
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Jan 1 from Des Moines to Amarillo, returning Tue, Jan 20, priced at $325 found 2 days ago

Alternative airports near Amarillo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Rick Husband Amarillo Intl. AMA. Cheapest option available. Average driving time to city center is 14 minutes. Flights from $436
AMA
Rick Husband Amarillo Intl.
Cheapest
Average driving time to city center14 min
Flights from $436

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA) cost?
Snag a cheap one-way flight from $146 or cheap return flight from $297 from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA)?
Flying in January may help you find better deals, as it's the cheapest month for flights between DSM and AMA. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA)?
To find the cheapest airline flying from DSM to AMA, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA)?
Direct flights from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DSM to AMA?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA)?
Select a flight from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA) that takes off before 3 PM to reduce the risk of cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA) last-minute?
Booking your ticket from DSM to AMA just before your getaway is generally more expensive. But if there's some wiggle room with your travel times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a DSM to AMA flight and hotel package?
Booking a DSM to AMA flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Pick from our impressive range of hotels and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Rick Husband Amarillo Intl. Airport (AMA)?
Typically, it's possible to reschedule or cancel your DSM to AMA flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Rick Husband Amarillo Intl.
Airlines serving
American Airlines, Southwest Airlines, United
Roundtrip price
$296
Distance
616 mi

Book with confidence

Des Moines to Amarillo Flights

The cheapest times to fly from Des Moines to Amarillo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Amarillo are during the month of January. You can find some of the cheapest flights from Des Moines to Amarillo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Amarillo

Sunday is one of the best days to book for cheap flights from Des Moines to Amarillo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Amarillo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Amarillo in 2026. You can also book with separate airlines for your outbound and return journeys, from $146 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Amarillo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Amarillo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Amarillo Flights

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*Available to One Key members.