$252 Cheap Flights from Des Moines (DSM) to Cartagena (CTG)

View $252 flight on Tue, Oct 7, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Rafael Nunez Intl. Airport (CTG)

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Cheap Flights from Des Moines to Cartagena (DSM-CTG)

Prices were available within the past 7 days and start at $252 for one-way flights and $566 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Dec 9 - Mon, Dec 22
DSM
Des Moines
CTG
Cartagena
$566 Roundtrip, found 3 days ago
$566
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Dec 9 from Des Moines to Cartagena, returning Mon, Dec 22, priced at $566 found 3 days ago
Delta
Tue, Nov 18 - Wed, Dec 3
DSM
Des Moines
CTG
Cartagena
$569 Roundtrip, found 3 days ago
$569
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Nov 18 from Des Moines to Cartagena, returning Wed, Dec 3, priced at $569 found 3 days ago
American Airlines
Wed, Nov 19 - Wed, Nov 26
DSM
Des Moines
CTG
Cartagena
$570 Roundtrip, found 3 days ago
$570
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 19 from Des Moines to Cartagena, returning Wed, Nov 26, priced at $570 found 3 days ago
Delta
Mon, Nov 24 - Tue, Dec 9
DSM
Des Moines
CTG
Cartagena
$572 Roundtrip, found 3 days ago
$572
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Nov 24 from Des Moines to Cartagena, returning Tue, Dec 9, priced at $572 found 3 days ago
Delta
Mon, Apr 27 - Wed, May 13
DSM
Des Moines
CTG
Cartagena
$573 Roundtrip, found 3 days ago
$573
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Apr 27 from Des Moines to Cartagena, returning Wed, May 13, priced at $573 found 3 days ago
Delta
Mon, Nov 24 - Wed, Dec 10
DSM
Des Moines
CTG
Cartagena
$575 Roundtrip, found 3 days ago
$575
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Nov 24 from Des Moines to Cartagena, returning Wed, Dec 10, priced at $575 found 3 days ago
Delta
Sat, Apr 25 - Tue, May 12
DSM
Des Moines
CTG
Cartagena
$575 Roundtrip, found 3 days ago
$575
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Apr 25 from Des Moines to Cartagena, returning Tue, May 12, priced at $575 found 3 days ago
Delta
Wed, Apr 22 - Tue, May 12
DSM
Des Moines
CTG
Cartagena
$576 Roundtrip, found 3 days ago
$576
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Apr 22 from Des Moines to Cartagena, returning Tue, May 12, priced at $576 found 3 days ago
LATAM Airlines Group
Mon, Feb 9 - Tue, Feb 24
DSM
Des Moines
CTG
Cartagena
$596 Roundtrip, found 3 days ago
$596
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, Feb 9 from Des Moines to Cartagena, returning Tue, Feb 24, priced at $596 found 3 days ago
United
Fri, Apr 24 - Sun, May 10
DSM
Des Moines
CTG
Cartagena
$598 Roundtrip, found 3 days ago
$598
Roundtrip
found 3 days ago
Select United flight, departing Fri, Apr 24 from Des Moines to Cartagena, returning Sun, May 10, priced at $598 found 3 days ago

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG) cost?
Get a cheap one-way flight from $252 or cheap return flight from $566 from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
December is the cheapest month to fly from DSM to CTG. Planning your trip for the off-season is often the key to finding better fares.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
To find the cheapest airline that'll fly you from DSM to CTG, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
You'll need to take a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from DSM to CTG?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change depending on a range of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
To avoid possible delays on the Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG) route, aim to travel before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG) last-minute?
Waiting until right before your break to book your flight from DSM to CTG often results in higher prices. While you may come across some last-minute discounts, there's no guarantee. Keep your travel plans flexible for the best chance of getting a bargain.
Is it cheaper to book a DSM to CTG flight and hotel package?
You can save money by securing a DSM to CTG flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've chosen your preferred flights and accommodations, consider other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
In most cases, you can modify or cancel your DSM to CTG flight. However, additional fees may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need further details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Des Moines Intl.
Destination airport
Rafael Núñez Intl.
Airlines serving
LATAM Airlines Group
Roundtrip price
$565
Distance
2413 mi

Book with confidence

Book with confidence

Des Moines to Cartagena Flights

The cheapest times to fly from Des Moines to Cartagena

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Cartagena are during the month of December. You can find some of the cheapest flights from Des Moines to Cartagena with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Cartagena

Sunday is one of the best days to book for cheap flights from Des Moines to Cartagena: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Cartagena

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Cartagena in 2025. You can also book with separate airlines for your outbound and return journeys, from $252 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Cartagena flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Cartagena airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Cartagena Flights

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