Photo by LJ Alan

Find 5 Star Hotels in San Diego from $105

Most hotels are fully refundable. Because flexibility matters.

Save 10% or more on over 100,000 hotels worldwide as a One Key member.

Search over 2.9 million properties and 550 airlines worldwide.

Compare San Diego 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Sofitel Baru Calablanca
Premium bedding, minibar, in-room safe, desk
Sofitel Baru Calablanca
5.0 star property
9.4 out of 10, Exceptional, (301)
"This property surpassed my expectations. The food was amazing. The staff made me feel at home and was very accommodating. I am so looking forward to coming back to this hotel. "
The price is $320
$320 total
includes taxes & fees
May 7 - May 8
Sofitel Baru Calablanca
Sofitel Legend Santa Clara Cartagena
Outdoor pool, pool umbrellas
Sofitel Legend Santa Clara Cartagena
5.0 star property
9.4 out of 10, Exceptional, (830)
"This place is simply magical! "
The price is $320
$320 total
includes taxes & fees
May 7 - May 8
Sofitel Legend Santa Clara Cartagena
Hotel Caribe by Faranda Grand, a member of Radisson Individuals
Aerial view
Hotel Caribe by Faranda Grand, a member of Radisson Individuals
5.0 star property
8.6 out of 10, Excellent, (1001)
"Simply the nicest resort...five stars "
The price is $202
$202 total
includes taxes & fees
Jun 2 - Jun 3
Hotel Caribe by Faranda Grand, a member of Radisson Individuals
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Casa De Alba Hotel Boutique
2 outdoor pools, sun loungers
Casa De Alba Hotel Boutique
5.0 star property
9.8 out of 10, Exceptional, (38)
"The staff were extremely friendly and helpful!"
The price is $335
$335 total
includes taxes & fees
May 6 - May 7
Casa De Alba Hotel Boutique
Leones de Alba Hotel Boutique
2 outdoor pools, sun loungers
Leones de Alba Hotel Boutique
5.0 star property
9.2 out of 10, Wonderful, (26)
"My experience was beyond met while staying at Leones De Alba! The breakfast, customer service and location was perfect. We definitely will be back. "
The price is $331
$331 total
includes taxes & fees
May 7 - May 8
Leones de Alba Hotel Boutique
Charleston Santa Teresa Cartagena
Outdoor pool, open 7:00 AM to 6:00 PM, pool umbrellas, sun loungers
Charleston Santa Teresa Cartagena
5.0 star property
9.2 out of 10, Wonderful, (608)
"Hands down, best hotel I’ve been to and I’ve travelled everywhere. Amazing food, service, view 10/10 Im going back in 2 months."
The price is $304
$304 total
includes taxes & fees
May 5 - May 6
Charleston Santa Teresa Cartagena
Apartaestudio DM-7S con Piscina y Wifi
Exterior
Apartaestudio DM-7S con Piscina y Wifi
5.0 star property
Apartaestudio DM-7S con Piscina y Wifi
2CB-4 APARTAMENTO DE 2 ALC EN GETSEMANI
Standard Apartment | Private kitchenette | Fridge, dishwasher, blender, cookware/dishes/utensils
2CB-4 APARTAMENTO DE 2 ALC EN GETSEMANI
5.0 star property
The price is $128
$184 total
includes taxes & fees
May 18 - May 19
2CB-4 APARTAMENTO DE 2 ALC EN GETSEMANI
Apartamento 2CBM-1 Cerca al Mar con Wifi
Exterior
Apartamento 2CBM-1 Cerca al Mar con Wifi
5.0 star property
Apartamento 2CBM-1 Cerca al Mar con Wifi

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Diego.
Hyatt Regency Cartagena

Hyatt Regency Cartagena

Carrera 1 No 12-118, Cartagena, CO
The price is $228 per night from May 5 to May 6
$228
$228 total
includes taxes & fees
May 5 - May 6
9.2/10 Wonderful! (1,304 reviews)
Still don't see what you're looking for?
See all properties in San Diego.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Ready to experience the next standard in luxury? We know you are thinking about it. Add an extra layer of pleasure on your next trip to San Diego by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to San Diego any longer. You'll join the multitudes of vacationers who have made San Diego so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve an outstanding getaway. Reserve one of our 5-star hotels in San Diego and indulge in the finer things in life for a while.

Book the Best San Diego 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and rejuvenating spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A mud wrap treatment that will leave you feeling great? Butler services? No matter what you want on a perfect getaway, you're bound to find it here.

Ready for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in San Diego are the perfect place to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and San Diego 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Pick out one of the 5-star hotels in San Diego today and dive into in luxe surroundings when you're ready.

Frequently asked questions

What are the best 5-star hotels in San Diego?
Offering world-class amenities and guest services, Expedia travelers rate Sofitel Legend Santa Clara Cartagena as one of the leading 5-star hotels in San Diego. You’ll be in the lap of luxury from the moment you step into the lobby.
How much does it cost to stay in a 5-star hotel in San Diego?
The amount you pay for a 5-star hotel in San Diego can vary based on when you decide to travel and how long you plan to stay, among a number of factors. Use our price per night filter and other search tools to find the best rate on a high-end stay.

  • Search for the lowest price per night from $105

What makes a hotel 5 stars in San Diego?
Impeccable guest service is at the heart of every 5-star hotel in San Diego. From the moment you enter the lobby, staff are at your beck and call, whether offering luggage assistance and storage or providing a turn-down service. On top of that, hotels have to feature top-rate amenities to qualify for a 5-star rating. These can include luxury bathrooms, spas or saunas, pools, fine dining restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in San Diego?
Find an upscale stay that includes your room, meals, drinks and entertainment in San Diego with the help of Expedia’s filters. Search for resorts rated 5 stars and select the “All inclusive” filter. Double-check what’s included in the upfront price. That way, you’ll be ready to maximize the premium perks on offer when you get there.
What are the top 5-star spa hotels in San Diego?
Sofitel Legend Santa Clara Cartagena combines upscale accommodations with relaxing wellness programs and experiences. Select from a menu of massages, facials and more at this leading 5-star spa stay in San Diego.
Does San Diego have any 5-star family resorts?
Kick back in style at Sofitel Legend Santa Clara Cartagena, a 5-star San Diego retreat that promises relaxation and excitement for your entire group. Make the most of the services and conveniences here that cater to the needs of both youngsters and adults.
Are there any 5-star vacation rentals in San Diego?
Although you won’t find any 5-star vacation rentals in San Diego on our site, we have a range of properties that promise a memorable getaway. Find one that suits your style by searching our vacation rentals in San Diego.
Are there any 5-star hotels in downtown San Diego?
Explore downtown San Diego from Sofitel Legend Santa Clara Cartagena. Stay at this 5-star hotel and enjoy easy access to some top sights and activities.

Recent reviews of San Diego hotels
Expedia verified reviews

Sofitel Baru Calablanca

Sofitel Baru Calablanca

5/5 Excellent
"This property surpassed my expectations. The food was amazing. The staff made me feel at home and was very accommodating. I am so looking forward to coming back to this hotel. "
A verified traveler stayed at Sofitel Baru Calablanca
Posted 5 days ago
Sofitel Baru Calablanca
Sofitel Legend Santa Clara Cartagena

Sofitel Legend Santa Clara Cartagena

5/5 Excellent
"This place is simply magical! "
A verified traveler stayed at Sofitel Legend Santa Clara Cartagena
Posted 6 days ago
Sofitel Legend Santa Clara Cartagena