$115 Cheap Flights from Des Moines (DSM) to Houston (HOU)

View $115 flight on Sat, Nov 22, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Houston William Hobby Airport (HOU)

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Cheap Flights from Des Moines to Houston (DSM-HOU)

Prices were available within the past 7 days and start at $115 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Sun, Nov 9 - Thu, Nov 13
DSM
Des Moines
HOU
Houston
$229 Roundtrip, found 1 hour ago
$229
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Sun, Nov 9 from Des Moines to Houston, returning Thu, Nov 13, priced at $229 found 1 hour ago
Southwest Airlines
Fri, Jan 23 - Sun, Jan 25
DSM
Des Moines
HOU
Houston
$234 Roundtrip, found 2 hours ago
$234
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Fri, Jan 23 from Des Moines to Houston, returning Sun, Jan 25, priced at $234 found 2 hours ago
Delta
Thu, Nov 27 - Tue, Dec 2
DSM
Des Moines
HOU
Houston
$237 Roundtrip, found 5 hours ago
$237
Roundtrip
found 5 hours ago
Select Delta flight, departing Thu, Nov 27 from Des Moines to Houston, returning Tue, Dec 2, priced at $237 found 5 hours ago
Southwest Airlines
Tue, Oct 28 - Tue, Nov 4
DSM
Des Moines
HOU
Houston
$239 Roundtrip, found 6 hours ago
$239
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Tue, Oct 28 from Des Moines to Houston, returning Tue, Nov 4, priced at $239 found 6 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Houston (HOU)

November is typically the cheapest month to fly

From $147 - $358 per traveler.

Alternative airports near Houston

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to George Bush Intercontinental IAH. Cheapest option available. Average driving time to city center is 24 minutes. Flights from $219
IAH
George Bush Intercontinental
Cheapest
Average driving time to city center24 min
Flights from $219

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU) cost?
Secure a cheap one-way flight from $115 or cheap return flight from $229 from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU)?
The cheapest month to fly from DSM to HOU is November, when demand is low. Off-peak months are often when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from DSM to HOU. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU)?
There aren't any daily direct flights available from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from DSM to HOU?
Typically you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU)?
Book a flight from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU) that leaves before 3 PM to reduce the risk of cancellations. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Houston from Des Moines Intl. Airport (DSM)?
George Bush Intercontinental Airport (IAH) is the only airport in Houston with direct flights from Des Moines Intl. Airport (DSM). Consider the options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU) last-minute?
Holding off until just before your departure to book a ticket from DSM to HOU generally means paying more. While you might find some last-minute deals, they aren't always guaranteed. Keep your travel plans flexible for a better chance of getting a bargain.
Is it cheaper to book a DSM to HOU flight and hotel package?
Booking a DSM to HOU flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Choose from our wide range of accommodations and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to William P. Hobby Airport (HOU)?
In most instances, you can reschedule or cancel your DSM to HOU flight. However, additional charges may apply, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you want further information, head to our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
William P. Hobby
Airlines serving
American Airlines, Delta, Southwest Airlines
Roundtrip price
$228
Distance
825 mi

Book with confidence

Des Moines to Houston Flights

The cheapest times to fly from Des Moines to Houston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Houston are during the month of November. You can find some of the cheapest flights from Des Moines to Houston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Houston

Sunday is one of the best days to book for cheap flights from Des Moines to Houston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Houston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Houston in 2025. You can also book with separate airlines for your outbound and return journeys, from $115 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Houston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Houston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Houston Flights

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*Available to One Key members.