$243 Cheap Flights from Des Moines (DSM) to McAllen (MFE)
Popular airlines from Des Moines International Airport (DSM) to Miller Intl. Airport (MFE)
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Cheap Flights from Des Moines to McAllen (DSM-MFE)
Alternative airports near McAllen
Prices were available within the past 7 days. Prices and availability are subject to change.
Find the cheapest month to fly from Des Moines (DSM) to McAllen (MFE)
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Des Moines (DSM) to McAllen (MFE) at a glance
Travel from Des Moines (DSM) to McAllen (MFE) with a selection of airlines catering to this domestic short-haul route. Search for McAllen flights that match your budget and schedule, offering everything from full-service options to more economical choices. As you plan your visit to McAllen's renowned attractions and neighborhoods, gather all the essential details for your journey from Des Moines International Airport (DSM) to Miller International Airport (MFE).
- Fastest flight duration: around 3h 45m in-flight, plus roughly 1h 15m layover with one stop
- Route distance: roughly 1,100 miles (1,770 km)
- Flights per week: around 9 departures on average
- Typical fares (one-way): economy tickets often range from $125–$350, depending on seasonality and how far ahead you book
Flights from Des Moines International Airport (DSM) to Miller International Airport (MFE)
Based on the latest traveler bookings, here are the top airlines favored for flights from Des Moines to McAllen, especially for one-stop and multi-stop options. Popular layover points include Dallas-Fort Worth International Airport (DFW), with a layover of approximately 1 hour and 15 minutes, and George Bush Intercontinental Airport (IAH), also around 1 hour and 15 minutes. This variety allows you to compare prices, total travel times, and cabin classes to find the ideal itinerary.
- American Airlines: As a comprehensive airline providing one-stop services, American Airlines dominates this route with about 74% of departures. One-way ticket prices generally fall between $125 and $390, with an in-flight duration of 3 hours 45 minutes and a total travel time of approximately 5 hours 15 minutes, including layovers.
- United: This full-service airline also offers one-stop services and represents roughly 25% of departures on this route. One-way fares typically range from $130 to $375. Passengers can expect an in-flight time of 3 hours 45 minutes, resulting in a total journey time of around 5 hours 15 minutes, factoring in layovers.
- Delta: Operating with a multi-stop service model, Delta accounts for about 2% of flights on this route. One-way fares usually vary from $150 to $255, featuring an in-flight duration of 6 hours and a total travel time close to 10 hours, including layover periods.
Travelers have the option to elevate their journey from Des Moines to McAllen with American Airlines' first-class service on this route.
Best time to fly from Des Moines (DSM) to McAllen (MFE)
The most popular months for travelers flying from Des Moines to McAllen are January, February, and March, when peak temperatures in McAllen reach up to 71.2°F in March. If you prefer quieter travel, consider October, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 78.4°F. For better deals, May usually offers the lowest average one-way fare around $195. Flight availability peaks in February and September, with approximately 10 flights per week, making it easier to find convenient departure times.
- Cheapest time to fly: May usually offers good deals with average one-way fare around $195, roughly 18% cheaper than the yearly average.
- More budget-friendly months to fly: September, March, and August typically offer average one-way fares of around $198.
- Most flight options: February and September have the highest number of flights from Des Moines to McAllen, with approximately 10 flights per week, giving you more flexibility in scheduling your trip.
| Month | Temperature | Demand | Weekly Flights | Average one-way Fare |
| January | 62.1°F (16.7°C) | High | 8 | $206 |
| February | 65.5°F (18.6°C) | High | 10 | $213 |
| March | 71.2°F (21.8°C) | High | 8 | $197 |
| April | 76.8°F (24.9°C) | Average | 8 | $216 |
| May | 81.0°F (27.2°C) | Average | 9 | $195 |
| June | 84.9°F (29.4°C) | Low | 7 | $260 |
| July | 86.5°F (30.3°C) | Low | 9 | $431 |
| August | 88.0°F (31.1°C) | Average | 8 | $199 |
| September | 84.2°F (29.0°C) | Average | 10 | $196 |
| October | 78.4°F (25.8°C) | Low | 7 | $211 |
| November | 69.4°F (20.8°C) | Average | 8 | $265 |
| December | 64.4°F (18.0°C) | Average | 8 | $267 |
*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.
Alternative routes from Des Moines (DSM) to McAllen (MFE)
- Des Moines to Harlingen (DSM-HRL): Valley International Airport (HRL) lies approximately 36 miles from Miller International Airport (MFE). One-way economy prices for this route usually fall between $110 and $325, varying by season and how far in advance you book. Travelers can choose from both one-stop and multi-stop flights, with common layover points at Dallas-Fort Worth International Airport (DFW) and George Bush Intercontinental Airport (IAH). Major airlines serving this route include American Airlines and United, with first-class service also available.
- Des Moines to Brownsville (DSM-BRO): Brownsville-South Padre Island International Airport (BRO) is located about 54 miles from Miller International Airport (MFE). One-way economy fares on this route generally range from $130 to $310, influenced by the time of year and booking timing. This journey typically features one-stop flights, with popular layovers at Dallas-Fort Worth International Airport (DFW) and George Bush Intercontinental Airport (IAH). Leading carriers for this route are American Airlines and United, and first-class service can also be opted for.
How to find the best prices for flights from Des Moines (DSM) to McAllen (MFE)
Getting some of the best deals on flights from Des Moines to McAllen is all about timing and flexibility. Here are some key tips to help you save:
- Best times to book and fly: cheaper fares are generally available when booking at least two months in advance, although most travelers tend to book within two weeks. Morning departures, from 5 AM to 12 PM, usually offer lower prices and are the most popular times to fly. Additionally, flying on Wednesday often provides cheaper options, while Thursday remains the busiest travel day.
- Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
- Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find McAllen hotel and flight deals.
- Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
- Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
- Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.
*Members only. Savings vary and are not available on all bundles. Select hotels.
Arriving at Miller International Airport from Des Moines International Airport
McAllen welcomes travelers from Des Moines with a range of transport options based on price, convenience, and proximity. Here's how to reach McAllen efficiently:
- Hotel transfer: Transfers offer a convenient way to reach your hotel in McAllen, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
- Car rental: Renting a car from Miller International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Miller International Airport on Expedia.
- Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
Des Moines to McAllen Flights
The cheapest times to fly from Des Moines to McAllen
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to McAllen are during the month of December. You can find some of the cheapest flights from Des Moines to McAllen with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Des Moines to McAllen
Sunday is one of the best days to book for cheap flights from Des Moines to McAllen: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Des Moines to McAllen
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to McAllen in 2026. You can also book with separate airlines for your outbound and return journeys, from $243 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to McAllen flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to McAllen airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently Asked Questions
How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) cost?
You can find cheap one-way flights from $243 and cheap return flights $295 Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) with Expedia. One-way flights generally range between $187 and $885, and roundtrip flights usually range from $349 to $1281. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) ticket fares go up or down.
*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
March is the cheapest month to fly from Des Moines, IA (DSM) to McAllen, TX (MFE), with average round-trip fares around $342. This price is about 24% lower than the average throughout the year, as travel demand tends to dip after the winter months. Other affordable months to consider are April and May.
*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
Enter DSM to MFE and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Des Moines (DSM) to McAllen (MFE), with round-trip tickets starting from around $196.37 with a layover in O'Hare Intl. (ORD). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
To find a cheap flight from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
The best time to fly from Des Moines (DSM) to McAllen (MFE) is in March or April, with average return flight prices around $342. March is particularly appealing as it marks the beginning of spring, making it a great time to visit Texas.
*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
The earliest flight from Des Moines International Airport (DSM) to Miller International Airport (MFE) departs at 5:00 AM local time, operated by American Airlines. This seasonal service is active in January, November, and December, giving you an early start to your trip to McAllen. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
The most popular departure times for flights from Des Moines (DSM) to McAllen (MFE) are in the early morning, from 3am to 6am. About 24% of passengers prefer this time window. Many major carriers, including American Airlines, Delta and United Airlines, offer flights during this window. This timing works well because it allows you to arrive in McAllen with plenty of time to enjoy your day.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
Flights from DSM to MFE with one stop typically take around 5 hours, covering approximately 1,093 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
First class seats are offered on the DSM to MFE route. First class cabins are available on:
- American Airlines
- Delta Air Lines
- United Airlines
How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) flight with Expedia?
It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.
*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for McAllen from Des Moines Intl. (DSM)?
From Des Moines Intl. (DSM), you can fly into Miller Intl. (MFE) to reach McAllen. Some flights may connect through major hubs like O'Hare Intl. (ORD), Denver Intl. (DEN), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching McAllen. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) at the last minute?
Typically, booking a last minute flight from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) flight and hotel package?
Securing a Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) Mcallen Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.)?
If you booked your Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.
Travel information
Origin airport | Des Moines International Airport |
|---|---|
Destination airport | Miller Intl. Airport |
Distance | 1,092 miles away |
Airlines serving | American Airlines, United, Delta |
Popular airline | American Airlines |
Roundtrip price | $295 |