$168 Cheap Flights from Des Moines (DSM) to McAllen (MFE)

You can find cheap one-way flights from $168 and cheap return flights from $310 Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) with Expedia. One-way flights generally range between $187 and $885, and roundtrip flights usually range from $349 to $1281. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.

March is the cheapest month to fly from Des Moines, IA (DSM) to McAllen, TX (MFE), with average round-trip fares around $342. This price is about 24% lower than the average throughout the year, as travel demand tends to dip after the winter months. Other affordable months to consider are April and May.*Averages based on flights available on Expedia in the last year.

American Airlines is one of the cheapest airlines offering connecting flights from Des Moines (DSM) to McAllen (MFE), with round-trip tickets starting from around $196.37 with a layover in O'Hare Intl. (ORD). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.

The best time to fly from Des Moines (DSM) to McAllen (MFE) is in March or April, with average return flight prices around $342. March is particularly appealing as it marks the beginning of spring, making it a great time to visit Texas.*Prices based on flights available on Expedia in the last year.

First class seats are offered on the DSM to MFE route. First class cabins are available on:

• American Airlines
• Delta Air Lines
• United Airlines

It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to McAllen, TX (MFE-Miller Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.