$262 Cheap Flights from Key West (EYW) to Islip (ISP)

View $262 flight on Wed, Jan 14, 2026Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to MacArthur Airport (ISP)

Cheap Flights from Key West to Islip (EYW-ISP)

Prices were available within the past 7 days and start at $262 for one-way flights and $765 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Breeze Airways
Sat, Nov 8 - Wed, Nov 12
EYW
Key West
ISP
Islip
$765 Roundtrip, found 1 day ago
$765
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sat, Nov 8 from Key West to Islip, returning Wed, Nov 12, priced at $765 found 1 day ago
Breeze Airways
Sat, Nov 8 - Sun, Nov 9
EYW
Key West
ISP
Islip
$779 Roundtrip, found 1 day ago
$779
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sat, Nov 8 from Key West to Islip, returning Sun, Nov 9, priced at $779 found 1 day ago
Breeze Airways
Sat, Nov 8 - Mon, Nov 10
EYW
Key West
ISP
Islip
$783 Roundtrip, found 1 day ago
$783
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sat, Nov 8 from Key West to Islip, returning Mon, Nov 10, priced at $783 found 1 day ago
Breeze Airways
Sun, Nov 9 - Wed, Nov 12
EYW
Key West
ISP
Islip
$949 Roundtrip, found 1 day ago
$949
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sun, Nov 9 from Key West to Islip, returning Wed, Nov 12, priced at $949 found 1 day ago
Breeze Airways
Fri, Nov 7 - Sun, Nov 9
EYW
Key West
ISP
Islip
$960 Roundtrip, found 1 day ago
$960
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Fri, Nov 7 from Key West to Islip, returning Sun, Nov 9, priced at $960 found 1 day ago
Breeze Airways
Sun, Nov 9 - Mon, Nov 10
EYW
Key West
ISP
Islip
$967 Roundtrip, found 1 day ago
$967
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sun, Nov 9 from Key West to Islip, returning Mon, Nov 10, priced at $967 found 1 day ago
Delta
Fri, Nov 7 - Tue, Nov 11
EYW
Key West
ISP
Islip
$1,010 Roundtrip, found 1 day ago
$1,010
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Nov 7 from Key West to Islip, returning Tue, Nov 11, priced at $1,010 found 1 day ago

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to MacArthur Airport (ISP) cost?
Secure a cheap one-way flight from $262 or cheap return flight from $765 from Key West Intl. Airport (EYW) to MacArthur Airport (ISP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Key West Intl. Airport (EYW) to MacArthur Airport (ISP)?
Planning your getaway for November is a great way to save, as it's the cheapest month for flights between EYW and ISP. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Key West Intl. Airport (EYW) to MacArthur Airport (ISP)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll take you from EYW to ISP. Then, sort your results by "Price (lowest to highest)" to snap up a good deal.
How many flights per day from Key West Intl. Airport (EYW) to MacArthur Airport (ISP)?
Direct flights from Key West Intl. Airport (EYW) to MacArthur Airport (ISP) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from EYW to ISP?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Key West Intl. Airport (EYW) to MacArthur Airport (ISP)?
To avoid potential delays on the Key West Intl. Airport (EYW) to MacArthur Airport (ISP) route, fly before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Islip from Key West Intl. Airport (EYW)?
If you're boarding a direct flight from Key West Intl. Airport (EYW) to Islip, LaGuardia Airport (LGA) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to MacArthur Airport (ISP) last-minute?
Booking your flight from EYW to ISP shortly before your trip is usually more expensive. But if there's some wiggle room with your travel times and dates, you could score a cheap last-minute fare.
Is it cheaper to book an EYW to ISP flight and hotel package?
You'll typically save money by securing an EYW to ISP flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, consider adding extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to MacArthur Airport (ISP)?
Generally, it's possible to cancel or reschedule your EYW to ISP flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Key West Intl.
Destination airport
MacArthur
Roundtrip price
$764
Distance
1227 mi

Book with confidence

Key West to Islip Flights

The cheapest times to fly from Key West to Islip

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to Islip are during the month of November. You can find some of the cheapest flights from Key West to Islip with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Key West to Islip

Sunday is one of the best days to book for cheap flights from Key West to Islip: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Key West to Islip

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to Islip in 2025. You can also book with separate airlines for your outbound and return journeys, from $262 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to Islip flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to Islip airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Key West to Islip Flights

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*Available to One Key members.