$514 Cheap Flights from Rome (FCO) to St. Louis (STL)

View $514 flight on Sat, Nov 22, 2025Opens in a new window

Popular airlines from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to St. Louis Lambert Intl. Airport (STL)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Rome to St. Louis (FCO-STL)

Prices were available within the past 7 days and start at $514 for one-way flights and $645 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, Dec 13 - Sun, Dec 14
FCO
Rome
STL
St. Louis
$645 Roundtrip, found 3 days ago
$645
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Dec 13 from Rome to St. Louis, returning Sun, Dec 14, priced at $645 found 3 days ago
Lufthansa
Wed, Nov 26 - Sun, Nov 30
FCO
Rome
STL
St. Louis
$712 Roundtrip, found 5 days ago
$712
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Wed, Nov 26 from Rome to St. Louis, returning Sun, Nov 30, priced at $712 found 5 days ago
Lufthansa
Sun, Nov 23 - Mon, Dec 8
FCO
Rome
STL
St. Louis
$717 Roundtrip, found 5 days ago
$717
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Sun, Nov 23 from Rome to St. Louis, returning Mon, Dec 8, priced at $717 found 5 days ago
Lufthansa
Sun, Nov 23 - Mon, Dec 8
FCO
Rome
STL
St. Louis
$719 Roundtrip, found 5 days ago
$719
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Sun, Nov 23 from Rome to St. Louis, returning Mon, Dec 8, priced at $719 found 5 days ago
Air Canada
Wed, Nov 26 - Sun, Nov 30
FCO
Rome
STL
St. Louis
$720 Roundtrip, found 5 days ago
$720
Roundtrip
found 5 days ago
Select Air Canada flight, departing Wed, Nov 26 from Rome to St. Louis, returning Sun, Nov 30, priced at $720 found 5 days ago
Air Canada
Wed, Nov 26 - Sun, Nov 30
FCO
Rome
STL
St. Louis
$723 Roundtrip, found 5 days ago
$723
Roundtrip
found 5 days ago
Select Air Canada flight, departing Wed, Nov 26 from Rome to St. Louis, returning Sun, Nov 30, priced at $723 found 5 days ago
Air Canada
Wed, Oct 8 - Sun, Oct 12
FCO
Rome
STL
St. Louis
$723 Roundtrip, found 3 days ago
$723
Roundtrip
found 3 days ago
Select Air Canada flight, departing Wed, Oct 8 from Rome to St. Louis, returning Sun, Oct 12, priced at $723 found 3 days ago
Air Canada
Wed, Oct 8 - Sun, Oct 12
FCO
Rome
STL
St. Louis
$730 Roundtrip, found 3 days ago
$730
Roundtrip
found 3 days ago
Select Air Canada flight, departing Wed, Oct 8 from Rome to St. Louis, returning Sun, Oct 12, priced at $730 found 3 days ago
Brussels Airlines
Sun, Nov 23 - Mon, Dec 8
FCO
Rome
STL
St. Louis
$738 Roundtrip, found 5 days ago
$738
Roundtrip
found 5 days ago
Select Brussels Airlines flight, departing Sun, Nov 23 from Rome to St. Louis, returning Mon, Dec 8, priced at $738 found 5 days ago
American Airlines
Sat, Dec 13 - Fri, Jan 16
FCO
Rome
STL
St. Louis
$745 Roundtrip, found 3 days ago
$745
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Dec 13 from Rome to St. Louis, returning Fri, Jan 16, priced at $745 found 3 days ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $852
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $852

Frequently asked questions

How much does a flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL) cost?
Snag a cheap one-way flight from $514 or cheap return flight from $645 from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL)?
Traveling in December can help you save, as it's the cheapest month for flights between FCO and STL. You'll often find the lowest prices during off-peak months.
What is the cheapest airline that flies from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest FCO to STL flight.
How many flights per day from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL)?
Direct flights from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from FCO to STL?
Usually you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL)?
To avoid possible delays on the Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL) route, aim to fly before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Last-minute fares from FCO to STL are typically more expensive. To lock in the cheapest rates, start looking for flights well ahead of time. That said, if you can play around with your travel dates, you may land a cheap fare right before you leave.
Is it cheaper to book a FCO to STL flight and hotel package?
Securing a FCO to STL flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our wide range of hotels and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Lambert-St. Louis Intl. Airport (STL)?
It's generally possible to reschedule or cancel your FCO to STL flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Fiumicino - Leonardo da Vinci Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Delta, Finnair, Iberia, KLM, Lufthansa, Scandinavian Airlines, United
Roundtrip price
$644
Distance
5053 mi

Book with confidence

Book with confidence

Rome to St. Louis Flights

The cheapest times to fly from Rome to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Rome to St. Louis are during the month of December. You can find some of the cheapest flights from Rome to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Rome to St. Louis

Sunday is one of the best days to book for cheap flights from Rome to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Rome to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Rome to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $514 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Rome to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Rome to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Rome to St. Louis Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.