$281 Cheap Flights from Florence (FLO) to West Palm Beach (PBI)

View $281 flight on Sat, Nov 15, 2025Opens in a new window

Popular airlines from Florence, SC (FLO-Florence Regional) to Palm Beach Intl. Airport (PBI)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Florence to West Palm Beach (FLO-PBI)

Prices were available within the past 7 days and start at $281 for one-way flights and $426 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Dec 3 - Sat, Dec 13
FLO
Florence
PBI
West Palm Beach
$426 Roundtrip, found 13 hours ago
$426
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Dec 3 from Florence to West Palm Beach, returning Sat, Dec 13, priced at $426 found 13 hours ago
American Airlines
Thu, Nov 20 - Mon, Nov 24
FLO
Florence
PBI
West Palm Beach
$435 Roundtrip, found 19 hours ago
$435
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Nov 20 from Florence to West Palm Beach, returning Mon, Nov 24, priced at $435 found 19 hours ago
American Airlines
Wed, Nov 19 - Thu, Dec 4
FLO
Florence
PBI
West Palm Beach
$441 Roundtrip, found 13 hours ago
$441
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Nov 19 from Florence to West Palm Beach, returning Thu, Dec 4, priced at $441 found 13 hours ago
American Airlines
Mon, Nov 24 - Sat, Dec 6
FLO
Florence
PBI
West Palm Beach
$451 Roundtrip, found 13 hours ago
$451
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, Nov 24 from Florence to West Palm Beach, returning Sat, Dec 6, priced at $451 found 13 hours ago
American Airlines
Wed, Nov 5 - Sat, Nov 15
FLO
Florence
PBI
West Palm Beach
$456 Roundtrip, found 13 hours ago
$456
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Nov 5 from Florence to West Palm Beach, returning Sat, Nov 15, priced at $456 found 13 hours ago
American Airlines
Mon, Nov 24 - Wed, Dec 10
FLO
Florence
PBI
West Palm Beach
$457 Roundtrip, found 13 hours ago
$457
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, Nov 24 from Florence to West Palm Beach, returning Wed, Dec 10, priced at $457 found 13 hours ago
American Airlines
Wed, Oct 29 - Thu, Nov 13
FLO
Florence
PBI
West Palm Beach
$461 Roundtrip, found 13 hours ago
$461
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Oct 29 from Florence to West Palm Beach, returning Thu, Nov 13, priced at $461 found 13 hours ago
American Airlines
Sat, Oct 25 - Tue, Nov 11
FLO
Florence
PBI
West Palm Beach
$467 Roundtrip, found 13 hours ago
$467
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, Oct 25 from Florence to West Palm Beach, returning Tue, Nov 11, priced at $467 found 13 hours ago
American Airlines
Tue, Dec 2 - Sun, Dec 14
FLO
Florence
PBI
West Palm Beach
$468 Roundtrip, found 13 hours ago
$468
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, Dec 2 from Florence to West Palm Beach, returning Sun, Dec 14, priced at $468 found 13 hours ago
American Airlines
Wed, Oct 29 - Tue, Nov 4
FLO
Florence
PBI
West Palm Beach
$477 Roundtrip, found 13 hours ago
$477
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Oct 29 from Florence to West Palm Beach, returning Tue, Nov 4, priced at $477 found 13 hours ago

Alternative airports near West Palm Beach

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Palm Beach Intl. PBI. Cheapest and Closest option available. Average driving time to city center is 7 minutes. Flights from $502
PBI
Palm Beach Intl.
CheapestClosest
Average driving time to city center7 min
Flights from $502

Frequently asked questions

How much does a flight from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI) cost?
Secure a cheap one-way flight from $281 or cheap return flight from $426 from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI)?
December is the most affordable month to fly from FLO to PBI. Timing your trip outside of the busy season is often the key to finding better fares.
What is the cheapest airline that flies from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI)?
To find the cheapest airline flying from FLO to PBI, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI)?
You'll need to catch a flight with a layover if you're traveling from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from FLO to PBI?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change depending on a range of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI)?
To avoid possible delays on the Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI) route, aim to travel before 3 PM. Flights after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI) last-minute?
Holding off until right before your break to book a ticket from FLO to PBI generally means paying more. While you may find some last-minute deals, there's no guarantee. Be flexible with your travel plans for a better chance of getting a bargain.
Is it cheaper to book a FLO to PBI flight and hotel package?
You'll typically save money by booking a FLO to PBI flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After choosing your ideal accommodations and flights, consider adding extras including tours, activities and car rentals.
Can I cancel or change the date of my flight from Florence Regional Airport (FLO) to Palm Beach Intl. Airport (PBI)?
Typically, you can cancel or modify your FLO to PBI flight. However, additional fees may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you want further details, go to our Customer Service portal.

Travel information

Origin airport
Florence Regional
Destination airport
Palm Beach Intl.
Airlines serving
American Airlines
Roundtrip price
$425
Distance
518 mi

Book with confidence

Florence to West Palm Beach Flights

The cheapest times to fly from Florence to West Palm Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Florence to West Palm Beach are during the month of December. You can find some of the cheapest flights from Florence to West Palm Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Florence to West Palm Beach

Sunday is one of the best days to book for cheap flights from Florence to West Palm Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Florence to West Palm Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Florence to West Palm Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $281 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Florence to West Palm Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Florence to West Palm Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Florence to West Palm Beach Flights

Explore a world of travel with Expedia

*Available to One Key members.