$303 Cheap Flights from Florence (FLO) to Phoenix (PHX)

View $303 flight on Sat, Nov 8, 2025Opens in a new window

Popular airlines from Florence, SC (FLO-Florence Regional) to Phoenix Sky Harbor Intl. Airport (PHX)

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Cheap Flights from Florence to Phoenix (FLO-PHX)

Prices were available within the past 7 days and start at $303 for one-way flights and $403 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Apr 4 - Wed, Apr 8
FLO
Florence
PHX
Phoenix
$403 Roundtrip, found 16 hours ago
$403
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Sat, Apr 4 from Florence to Phoenix, returning Wed, Apr 8, priced at $403 found 16 hours ago
American Airlines
Sat, Nov 8 - Tue, Nov 11
FLO
Florence
PHX
Phoenix
$425 Roundtrip, found 1 day ago
$425
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Nov 8 from Florence to Phoenix, returning Tue, Nov 11, priced at $425 found 1 day ago
American Airlines
Thu, Jan 8 - Sat, Jan 10
FLO
Florence
PHX
Phoenix
$441 Roundtrip, found 3 days ago
$441
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jan 8 from Florence to Phoenix, returning Sat, Jan 10, priced at $441 found 3 days ago
American Airlines
Sat, Apr 4 - Wed, Apr 8
FLO
Florence
PHX
Phoenix
$458 Roundtrip, found 16 hours ago
$458
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Sat, Apr 4 from Florence to Phoenix, returning Wed, Apr 8, priced at $458 found 16 hours ago
American Airlines
Mon, May 11 - Wed, Jun 3
FLO
Florence
PHX
Phoenix
$462 Roundtrip, found 4 days ago
$462
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, May 11 from Florence to Phoenix, returning Wed, Jun 3, priced at $462 found 4 days ago
American Airlines
Thu, Nov 6 - Wed, Nov 12
FLO
Florence
PHX
Phoenix
$473 Roundtrip, found 3 days ago
$473
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Nov 6 from Florence to Phoenix, returning Wed, Nov 12, priced at $473 found 3 days ago
American Airlines
Thu, Jan 8 - Sat, Jan 10
FLO
Florence
PHX
Phoenix
$478 Roundtrip, found 3 days ago
$478
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jan 8 from Florence to Phoenix, returning Sat, Jan 10, priced at $478 found 3 days ago
American Airlines
Thu, Nov 6 - Wed, Nov 12
FLO
Florence
PHX
Phoenix
$490 Roundtrip, found 3 days ago
$490
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Nov 6 from Florence to Phoenix, returning Wed, Nov 12, priced at $490 found 3 days ago
American Airlines
Wed, Apr 1 - Wed, Apr 8
FLO
Florence
PHX
Phoenix
$493 Roundtrip, found 16 hours ago
$493
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Wed, Apr 1 from Florence to Phoenix, returning Wed, Apr 8, priced at $493 found 16 hours ago
American Airlines
Mon, May 11 - Wed, Jun 3
FLO
Florence
PHX
Phoenix
$497 Roundtrip, found 4 days ago
$497
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, May 11 from Florence to Phoenix, returning Wed, Jun 3, priced at $497 found 4 days ago

Alternative airports near Phoenix

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Sky Harbor Intl. PHX. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $552
PHX
Sky Harbor Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $552

Frequently asked questions

How much does a flight from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX) cost?
Snag a cheap one-way flight from $303 or cheap return flight from $403 from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX)?
The cheapest month to fly from FLO to PHX is April, when there's less demand. Off-peak months are generally when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX)?
To find the cheapest airline that'll fly you from FLO to PHX, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX)?
There aren't any daily nonstop flights departing from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way in no time at all.
What day of the week has the most flights from FLO to PHX?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX)?
Book a flight from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX) that leaves before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX) last-minute?
Booking your flight from FLO to PHX just before your journey is usually more expensive. However, if there's some wiggle room with your departure times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a FLO to PHX flight and hotel package?
Opting for a FLO to PHX flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Pick from our wide range of hotels and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Florence Regional Airport (FLO) to Sky Harbor Intl. Airport (PHX)?
If you reserved your FLO to PHX flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Florence Regional
Destination airport
Sky Harbor Intl.
Airlines serving
American Airlines
Roundtrip price
$402
Distance
1846 mi

Book with confidence

Florence to Phoenix Flights

The cheapest times to fly from Florence to Phoenix

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Florence to Phoenix are during the month of April. You can find some of the cheapest flights from Florence to Phoenix with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Florence to Phoenix

Sunday is one of the best days to book for cheap flights from Florence to Phoenix: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Florence to Phoenix

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Florence to Phoenix in 2025. You can also book with separate airlines for your outbound and return journeys, from $303 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Florence to Phoenix flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Florence to Phoenix airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Florence to Phoenix Flights

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*Available to One Key members.