$226 Cheap Flights from Orlando (MCO) to Santiago (SCL)

View $226 flight on Thu, Nov 27, 2025Opens in a new window

Popular airlines from Orlando Intl. Airport (MCO) to Santiago Intl. Airport (SCL)

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Cheap Flights from Orlando to Santiago (MCO-SCL)

Prices were available within the past 7 days and start at $226 for one-way flights and $448 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, Aug 20 - Wed, Aug 27
MCO
Orlando
SCL
Santiago
$448 Roundtrip, found 3 hours ago
$448
Roundtrip
found 3 hours ago
Select Copa flight, departing Wed, Aug 20 from Orlando to Santiago, returning Wed, Aug 27, priced at $448 found 3 hours ago
American Airlines
Thu, Nov 13 - Thu, Nov 20
MCO
Orlando
SCL
Santiago
$464 Roundtrip, found 2 hours ago
$464
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Nov 13 from Orlando to Santiago, returning Thu, Nov 20, priced at $464 found 2 hours ago
United
Tue, Nov 11 - Mon, Nov 17
MCO
Orlando
SCL
Santiago
$464 Roundtrip, found 2 hours ago
$464
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Nov 11 from Orlando to Santiago, returning Mon, Nov 17, priced at $464 found 2 hours ago
Copa
Wed, Aug 20 - Wed, Aug 27
MCO
Orlando
SCL
Santiago
$468 Roundtrip, found 3 hours ago
$468
Roundtrip
found 3 hours ago
Select Copa flight, departing Wed, Aug 20 from Orlando to Santiago, returning Wed, Aug 27, priced at $468 found 3 hours ago
United
Fri, Nov 7 - Fri, Nov 14
MCO
Orlando
SCL
Santiago
$468 Roundtrip, found 4 hours ago
$468
Roundtrip
found 4 hours ago
Select United flight, departing Fri, Nov 7 from Orlando to Santiago, returning Fri, Nov 14, priced at $468 found 4 hours ago
United
Mon, Oct 27 - Sat, Nov 1
MCO
Orlando
SCL
Santiago
$471 Roundtrip, found 7 hours ago
$471
Roundtrip
found 7 hours ago
Select United flight, departing Mon, Oct 27 from Orlando to Santiago, returning Sat, Nov 1, priced at $471 found 7 hours ago
American Airlines
Thu, Jul 17 - Mon, Jul 21
MCO
Orlando
SCL
Santiago
$474 Roundtrip, found 11 hours ago
$474
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Thu, Jul 17 from Orlando to Santiago, returning Mon, Jul 21, priced at $474 found 11 hours ago
American Airlines
Thu, Jul 17 - Sun, Aug 3
MCO
Orlando
SCL
Santiago
$477 Roundtrip, found 4 hours ago
$477
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Thu, Jul 17 from Orlando to Santiago, returning Sun, Aug 3, priced at $477 found 4 hours ago
Delta
Thu, Aug 28 - Thu, Sep 18
MCO
Orlando
SCL
Santiago
$479 Roundtrip, found 13 hours ago
$479
Roundtrip
found 13 hours ago
Select Delta flight, departing Thu, Aug 28 from Orlando to Santiago, returning Thu, Sep 18, priced at $479 found 13 hours ago
avianca
Wed, Aug 20 - Wed, Aug 27
MCO
Orlando
SCL
Santiago
$485 Roundtrip, found 3 hours ago
$485
Roundtrip
found 3 hours ago
Select avianca flight, departing Wed, Aug 20 from Orlando to Santiago, returning Wed, Aug 27, priced at $485 found 3 hours ago

Find the cheapest month to fly from Orlando (MCO) to Santiago (SCL)

May is typically the cheapest month to fly

From $397 - $720 per traveler.

Graph displaying average flight prices per month

Flights from Orlando (MCO) to Santiago (SCL)
Origin airport
Orlando Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United, avianca
Roundtrip price
$447
Distance
4326 mi

Orlando to Santiago Flights

The cheapest times to fly from Orlando to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Orlando to Santiago are during the month of August. You can find some of the cheapest flights from Orlando to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Orlando to Santiago

Sunday is one of the best days to book for cheap flights from Orlando to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Orlando to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Orlando to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $226 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Orlando to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Orlando to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL) cost?
Find cheap return fares from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL) starting from $479. Reserve your seat and take off on your trip. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Delta flight leaving MCO on July 10 2025 and touching down at SCL. The price was last updated on July 3 2025 and has not changed since.
What is the cheapest month to fly from MCO to SCL?
The cheapest flights from MCO to SCL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL)?
Fly directly from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL) on a LATAM Airlines flight.
What is the cheapest airline that flies from MCO to SCL?
With tickets starting at $351 for a one-way flight from MCO to SCL, Delta is currently the cheapest carrier on this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MCO on September 18 2025. Prices were last updated on July 3 2025 and have not changed since.
How many flights per day from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL)?
On average, you can pick from 2 direct flights every week from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL). For more flexibility, consider flights with layovers. Simply enter your details on Expedia and then filter your search to show one or two stops.
What are the most popular departure times for flights from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL)?
More people fly between MCO and SCL at 8 PM than at any other point in the day. Prefer a quieter experience? Consider flying outside peak hours and you could save on your fare as well.
What day of the week has the most flights from MCO to SCL?
Travel on a Thursday if you're after the largest selection of flights from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL).
What is the earliest flight from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL)?
Orlando Intl. Airport (MCO)'s first flight to Arturo Merino Benitez Airport (SCL) takes off at approximately 8:35PM UTC-5. With a travel duration of 8h 25m, you'll land at around 7:00AM UTC-3.
How long does it take to fly from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL)?
Flights from MCO to SCL have an average travel time of 8 hours and 25 minutes. The total distance between the two is 4,300 mi.
What airline has the least delays from MCO to SCL?
With 100% of flights usually arriving on time, LATAM Airlines has the best on-time performance for nonstop flights from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL). To keep track of your flight status and receive notifications about any changes, use the Expedia App.
What is the best time to fly from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL)?
To avoid possible delays on the Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL) route, fly before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Santiago from Orlando Intl. Airport (MCO)?
Check out your flight options from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL). This is the only airport in Santiago you can fly into if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL) last-minute?
Waiting until just before your trip to book your flight from MCO to SCL often results in higher prices. While you may find some last-minute deals, they aren't always guaranteed. Be flexible with your itinerary for the best chance of getting a bargain.
Is it cheaper to book a MCO to SCL flight and hotel package?
You can save money by securing a MCO to SCL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've chosen your preferred flights and accommodations, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Orlando Intl. Airport (MCO) to Arturo Merino Benitez Airport (SCL)?
If you reserved your MCO to SCL flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

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