$282 Cheap Flights from Orlando (MCO) to Tupelo (TUP)

View $282 flight on Tue, Dec 2, 2025Opens in a new window

Popular airlines from Orlando Intl. Airport (MCO) to Tupelo, MS (TUP-Tupelo Regional)

Cheap Flights from Orlando to Tupelo (MCO-TUP)

Prices were available within the past 7 days and start at $282 for one-way flights and $336 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Jan 9 - Mon, Jan 12
MCO
Orlando
TUP
Tupelo
$336 Roundtrip, found 2 days ago
$336
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Jan 9 from Orlando to Tupelo, returning Mon, Jan 12, priced at $336 found 2 days ago
American Airlines
Sun, Jan 11 - Wed, Jan 14
MCO
Orlando
TUP
Tupelo
$341 Roundtrip, found 2 days ago
$341
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jan 11 from Orlando to Tupelo, returning Wed, Jan 14, priced at $341 found 2 days ago
American Airlines
Thu, Dec 4 - Mon, Dec 8
MCO
Orlando
TUP
Tupelo
$373 Roundtrip, found 2 days ago
$373
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Dec 4 from Orlando to Tupelo, returning Mon, Dec 8, priced at $373 found 2 days ago
American Airlines
Fri, Jan 9 - Mon, Jan 12
MCO
Orlando
TUP
Tupelo
$382 Roundtrip, found 2 days ago
$382
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Jan 9 from Orlando to Tupelo, returning Mon, Jan 12, priced at $382 found 2 days ago
American Airlines
Thu, Dec 4 - Mon, Dec 8
MCO
Orlando
TUP
Tupelo
$408 Roundtrip, found 2 days ago
$408
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Dec 4 from Orlando to Tupelo, returning Mon, Dec 8, priced at $408 found 2 days ago
American Airlines
Fri, Jan 9 - Mon, Jan 12
MCO
Orlando
TUP
Tupelo
$416 Roundtrip, found 2 days ago
$416
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Jan 9 from Orlando to Tupelo, returning Mon, Jan 12, priced at $416 found 2 days ago
American Airlines
Fri, Jan 9 - Mon, Jan 12
MCO
Orlando
TUP
Tupelo
$427 Roundtrip, found 2 days ago
$427
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Jan 9 from Orlando to Tupelo, returning Mon, Jan 12, priced at $427 found 2 days ago
American Airlines
Thu, Dec 4 - Mon, Dec 8
MCO
Orlando
TUP
Tupelo
$428 Roundtrip, found 2 days ago
$428
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Dec 4 from Orlando to Tupelo, returning Mon, Dec 8, priced at $428 found 2 days ago
American Airlines
Mon, Jan 19 - Sun, Jan 25
MCO
Orlando
TUP
Tupelo
$432 Roundtrip, found 6 days ago
$432
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Jan 19 from Orlando to Tupelo, returning Sun, Jan 25, priced at $432 found 6 days ago
United
Tue, Jan 13 - Sun, Jan 18
MCO
Orlando
TUP
Tupelo
$455 Roundtrip, found 2 days ago
$455
Roundtrip
found 2 days ago
Select United flight, departing Tue, Jan 13 from Orlando to Tupelo, returning Sun, Jan 18, priced at $455 found 2 days ago

Frequently asked questions

How much does a flight from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP) cost?
Get a cheap one-way flight from $282 or cheap return flight from $336 from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP)?
January is the least expensive month to fly from MCO to TUP. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MCO to TUP flight.
How many flights per day from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP)?
Direct flights from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MCO to TUP?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change based on various factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP)?
Opt for a flight from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP) that leaves before 3 PM to reduce the likelihood of delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP) last-minute?
Last-minute fares from MCO to TUP are generally more expensive. For the best rates, start searching for flights well in advance. That being said, if you're flexible with your travel dates, you may score a cheap fare right before your journey.
Is it cheaper to book a MCO to TUP flight and hotel package?
You'll generally save money by securing a MCO to TUP flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Orlando Intl. Airport (MCO) to Tupelo Regional Airport (TUP)?
If you reserved your MCO to TUP flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for further details.

Travel information

Origin airport
Orlando Intl.
Destination airport
Tupelo Regional
Roundtrip price
$336
Distance
596 mi

Book with confidence

Orlando to Tupelo Flights

The cheapest times to fly from Orlando to Tupelo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Orlando to Tupelo are during the month of January. You can find some of the cheapest flights from Orlando to Tupelo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Orlando to Tupelo

Sunday is one of the best days to book for cheap flights from Orlando to Tupelo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Orlando to Tupelo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Orlando to Tupelo in 2025. You can also book with separate airlines for your outbound and return journeys, from $282 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Orlando to Tupelo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Orlando to Tupelo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Orlando to Tupelo Flights

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*Available to One Key members.