Cheap Flights from Chicago (MDW) to St. Louis (CPS)

Popular airlines from Chicago Midway Airport (MDW) to St. Louis, MO (CPS-St. Louis Downtown)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $439
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $439

Frequently asked questions

How much does a flight from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS) cost?
Snag a cheap one-way flight or cheap return flight from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS)?
The cheapest month to fly from MDW to CPS is , when there's less demand. Off-peak season is usually when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MDW to CPS flight.
How many flights per day from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS)?
There are no daily nonstop flights from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from MDW to CPS?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS)?
To touch down at St. Louis Downtown Airport (CPS) on time, choose a flight that takes off from Midway Intl. Airport (MDW) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for East St. Louis from Midway Intl. Airport (MDW)?
If you're taking a direct flight from Midway Intl. Airport (MDW) to East St. Louis, Lambert-St. Louis Intl. Airport (STL) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS) last-minute?
Booking your flight from MDW to CPS just before your getaway is typically more expensive. However, if you're flexible with your departure dates and times, you could score a cheap last-minute fare.
Is it cheaper to book a MDW to CPS flight and hotel package?
Securing a MDW to CPS flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our impressive range of accommodations and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Midway Intl. Airport (MDW) to St. Louis Downtown Airport (CPS)?
It's generally possible to reschedule or cancel your MDW to CPS flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Midway Intl.
Destination airport
St. Louis Downtown
Distance
255 mi

Book with confidence

Chicago to St. Louis Flights

The cheapest times to fly from Chicago to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to St. Louis are during the month of . You can find some of the cheapest flights from Chicago to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to St. Louis

Sunday is one of the best days to book for cheap flights from Chicago to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Chicago to St. Louis Flights

Explore a world of travel with Expedia

*Available to One Key members.