$279 Cheap Flights from Moline (MLI) to Houston (HOU)

View $279 flight on Thu, May 21, 2026Opens in a new window

Popular airlines from Quad City Intl. Airport (MLI) to Houston William Hobby Airport (HOU)

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Cheap Flights from Moline to Houston (MLI-HOU)

Prices were available within the past 7 days and start at $279 for one-way flights and $243 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Jun 3 - Tue, Jun 9
MLI
Moline
HOU
Houston
$243 Roundtrip, just found
$243
Roundtrip
just found
Select Delta flight, departing Wed, Jun 3 from Moline to Houston, returning Tue, Jun 9, priced at $243 just found
Delta
Sat, May 23 - Wed, May 27
MLI
Moline
HOU
Houston
$263 Roundtrip, found 3 days ago
$263
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, May 23 from Moline to Houston, returning Wed, May 27, priced at $263 found 3 days ago
Delta
Fri, May 8 - Tue, May 12
MLI
Moline
HOU
Houston
$306 Roundtrip, found 1 day ago
$306
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, May 8 from Moline to Houston, returning Tue, May 12, priced at $306 found 1 day ago

Alternative airports near Houston

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to George Bush Intercontinental IAH. Cheapest option available. Average driving time to city center is 24 minutes. Flights from $354
IAH
George Bush Intercontinental
Cheapest
Average driving time to city center24 min
Flights from $354

Frequently asked questions

How much does a flight from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) cost?
You can find cheap one-way flights from $279 and cheap return flights from $243 Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) with Expedia. One-way flights usually range from $238 to $595, and return flights typically cost between $315 and $978. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
May is the cheapest month to fly from Moline (MLI) to Houston (HOU), with average round-trip fares around $278. This price is about 22% lower than the average throughout the year, as May typically sees a decrease in travel demand. Other economical months to consider are September and November.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
Enter MLI to HOU and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
American Airlines is one of the cheapest airlines offering connecting flights from Moline, IL (MLI) to Houston, TX (HOU), with round-trip tickets starting from around $202 with a layover in O'Hare Intl. (ORD). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
To find a cheap flight from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
For flights from Moline, IL (MLI) to Houston, TX (HOU), May and September are the best months to consider. You can find return flights for around $278 in May, making it a budget-friendly option. September also offers good weather and fewer crowds, providing a pleasant travel experience. Both months strike a nice balance between cost and enjoyment.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
The earliest flight from Moline, IL (MLI) to Houston, TX (HOU) typically leaves at around 5:00 AM, operated by American Airlines. This seasonal service is available in January, February, May, June, and July, allowing you to start your day early and make the most of your time in Houston. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
The most popular departure times for flights from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) are in the early morning, from 6am to 9am. About 29% of passengers prefer this time window. Many major carriers, including American Airlines and United Airlines, offer flights during this window. This timing works well because it allows you to start your day early and arrive in Houston with plenty of time to enjoy your day.
How long does it take to fly from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
A flight from MLI to HOU with a layover takes around 5 hours 30 minutes, with the route covering approximately 858 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
First class seats are offered on the MLI to HOU route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) flight with Expedia?
It's easy to earn miles on a Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Houston from Quad City Intl. (MLI)?
From Quad City Intl. (MLI), you can fly into William P. Hobby (HOU) and George Bush Intercontinental (IAH) in Houston. Some flights may connect through major hubs like O'Hare Intl. (ORD), Charlotte-Douglas Intl. (CLT), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Houston. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) at the last minute?
Typically, booking a last minute flight from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) flight and hotel package?
Securing a Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) Houston Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby)?
If you booked your Moline, IL (MLI-Quad City Intl.) to Houston, TX (HOU-William P. Hobby) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Quad City Intl.
Destination airport
William P. Hobby
Airlines serving
American Airlines, Delta
Roundtrip price
$242
Distance
857 mi

*Flight schedules are subject to change.

*Available to One Key members.

 

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