$50 Cheap Flights from Myrtle Beach (MYR) to Chicago (ORD)

View $50 flight on Sun, Aug 31, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Chicago O'Hare Intl. Airport (ORD)

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Cheap Flights from Myrtle Beach to Chicago (MYR-ORD)

Prices were available within the past 7 days and start at $50 for one-way flights and $131 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Sat, Aug 30 - Sun, Aug 31
MYR
Myrtle Beach
ORD
Chicago
$131 Roundtrip, found 6 hours ago
$131
Roundtrip
found 6 hours ago
Select Spirit Airlines flight, departing Sat, Aug 30 from Myrtle Beach to Chicago, returning Sun, Aug 31, priced at $131 found 6 hours ago
Spirit Airlines
Sun, Aug 31 - Thu, Sep 4
MYR
Myrtle Beach
ORD
Chicago
$138 Roundtrip, found 3 hours ago
$138
Roundtrip
found 3 hours ago
Select Spirit Airlines flight, departing Sun, Aug 31 from Myrtle Beach to Chicago, returning Thu, Sep 4, priced at $138 found 3 hours ago
Spirit Airlines
Thu, Aug 28 - Sun, Aug 31
MYR
Myrtle Beach
ORD
Chicago
$138 Roundtrip, just found
$138
Roundtrip
just found
Select Spirit Airlines flight, departing Thu, Aug 28 from Myrtle Beach to Chicago, returning Sun, Aug 31, priced at $138 just found
Spirit Airlines
Sun, Aug 31 - Thu, Sep 4
MYR
Myrtle Beach
ORD
Chicago
$140 Roundtrip, found 3 hours ago
$140
Roundtrip
found 3 hours ago
Select Spirit Airlines flight, departing Sun, Aug 31 from Myrtle Beach to Chicago, returning Thu, Sep 4, priced at $140 found 3 hours ago
Spirit Airlines
Thu, Aug 28 - Wed, Sep 3
MYR
Myrtle Beach
ORD
Chicago
$145 Roundtrip, found 4 days ago
$145
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Thu, Aug 28 from Myrtle Beach to Chicago, returning Wed, Sep 3, priced at $145 found 4 days ago
Spirit Airlines
Sat, Aug 30 - Sun, Aug 31
MYR
Myrtle Beach
ORD
Chicago
$149 Roundtrip, found 6 hours ago
$149
Roundtrip
found 6 hours ago
Select Spirit Airlines flight, departing Sat, Aug 30 from Myrtle Beach to Chicago, returning Sun, Aug 31, priced at $149 found 6 hours ago
Southwest Airlines
Tue, Sep 23 - Wed, Sep 24
MYR
Myrtle Beach
ORD
Chicago
$209 Roundtrip, found 3 days ago
$209
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Sep 23 from Myrtle Beach to Chicago, returning Wed, Sep 24, priced at $209 found 3 days ago
Frontier Airlines
Thu, Sep 18 - Sun, Sep 21
MYR
Myrtle Beach
ORD
Chicago
$239 Roundtrip, found 1 hour ago
$239
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Thu, Sep 18 from Myrtle Beach to Chicago, returning Sun, Sep 21, priced at $239 found 1 hour ago
United
Thu, Sep 25 - Mon, Sep 29
MYR
Myrtle Beach
ORD
Chicago
$261 Roundtrip, found 2 hours ago
$261
Roundtrip
found 2 hours ago
Select United flight, departing Thu, Sep 25 from Myrtle Beach to Chicago, returning Mon, Sep 29, priced at $261 found 2 hours ago
Delta
Fri, Oct 3 - Sat, Oct 4
MYR
Myrtle Beach
ORD
Chicago
$281 Roundtrip, found 2 hours ago
$281
Roundtrip
found 2 hours ago
Select Delta flight, departing Fri, Oct 3 from Myrtle Beach to Chicago, returning Sat, Oct 4, priced at $281 found 2 hours ago

Find the cheapest month to fly from Myrtle Beach (MYR) to Chicago (ORD)

October is typically the cheapest month to fly

From $48 - $255 per traveler.

Graph displaying average flight prices per month

Alternative airports near Chicago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Midway Intl. MDW. Closest option available. Average driving time to city center is 16 minutes. Flights from $513
MDW
Midway Intl.
Closest
Average driving time to city center16 min
Flights from $513
Flights from Myrtle Beach (MYR) to Chicago (ORD)
Origin airport
Myrtle Beach Intl.
Destination airport
O'Hare Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, Spirit Airlines, United
Roundtrip price
$131
Distance
753 mi
Average flight time
2 hours 20 mins

Myrtle Beach to Chicago Flights

The cheapest times to fly from Myrtle Beach to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Chicago are during the month of August. You can find some of the cheapest flights from Myrtle Beach to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Chicago

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $50 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD) cost?
Grab a cheap one-way flight from $50 or cheap return flight from $131 from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD)?
The cheapest month to fly from MYR to ORD is August, when there's less demand. Off-peak season is usually when better flight deals are available between these airports.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MYR to ORD flight.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD)?
You'll have to hop on a flight with a layover if you're traveling from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from MYR to ORD?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from MYR to ORD?
Consider traveling with United Airlines if you'd like to go straight from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD) without any holdups. This carrier has the best track record for punctuality, with an on-time score of 85%. Want to be notified if anything changes? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD)?
To avoid possible delays on the Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD) route, aim to fly before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Chicago from Myrtle Beach Intl. Airport (MYR)?
Explore your flight options from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW). This is the only Chicago airport you can land at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD) last-minute?
Booking your plane ticket from MYR to ORD shortly before your journey is typically more expensive. But if there's some wiggle room with your travel times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a MYR to ORD flight and hotel package?
You can save money by booking a MYR to ORD flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After selecting your preferred flights and accommodations, consider adding extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to O'Hare Intl. Airport (ORD)?
It's usually possible to reschedule or cancel your MYR to ORD flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.