Cheap Flights from Fort Myers (RSW) to St. Louis (CPS)

Popular airlines from Southwest Florida Intl. Airport (RSW) to St. Louis, MO (CPS-St. Louis Downtown)

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Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $424
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $424

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS) cost?
Snag a cheap one-way flight or cheap return flight from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS)?
Flying in can help you save, as it's the cheapest month for flights between RSW and CPS. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest RSW to CPS flight.
How many flights per day from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS)?
Nonstop flights from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from RSW to CPS?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change based on a range of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS)?
To avoid potential delays on the Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS) route, aim to fly before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for East St. Louis from Southwest Florida Intl. Airport (RSW)?
Explore your flight options from Southwest Florida Intl. Airport (RSW) to Lambert-St. Louis Intl. Airport (STL). This is the only East St. Louis airport you can land at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS) last-minute?
Booking your ticket from RSW to CPS just before your journey is usually more expensive. However, if you're flexible with your itinerary, you could land a cheap last-minute fare.
Is it cheaper to book a RSW to CPS flight and hotel package?
You'll generally save money by booking a RSW to CPS flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. After choosing your preferred accommodations and flights, you can add extras like car rentals, tours and activities.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to St. Louis Downtown Airport (CPS)?
Usually, it's possible to reschedule or cancel your RSW to CPS flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Southwest Florida Intl.
Destination airport
St. Louis Downtown
Distance
964 mi

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Fort Myers to St. Louis Flights

The cheapest times to fly from Fort Myers to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to St. Louis are during the month of . You can find some of the cheapest flights from Fort Myers to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Myers to St. Louis

Sunday is one of the best days to book for cheap flights from Fort Myers to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Myers to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Fort Myers to St. Louis Flights

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