$345 Cheap Flights from Santo Domingo (SDQ) to Santiago (SCL)

View $345 flight on Wed, Mar 11, 2026Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Santiago Intl. Airport (SCL)

Cheap Flights from Santo Domingo to Santiago (SDQ-SCL)

Prices were available within the past 7 days and start at $345 for one-way flights and $539 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, Nov 13 - Tue, Nov 18
SDQ
Santo Domingo
SCL
Santiago
$539 Roundtrip, found 5 hours ago
$539
Roundtrip
found 5 hours ago
Select Copa flight, departing Thu, Nov 13 from Santo Domingo to Santiago, returning Tue, Nov 18, priced at $539 found 5 hours ago
Copa
Thu, Nov 20 - Mon, Nov 24
SDQ
Santo Domingo
SCL
Santiago
$563 Roundtrip, found 11 hours ago
$563
Roundtrip
found 11 hours ago
Select Copa flight, departing Thu, Nov 20 from Santo Domingo to Santiago, returning Mon, Nov 24, priced at $563 found 11 hours ago
Copa
Mon, Nov 10 - Sun, Nov 16
SDQ
Santo Domingo
SCL
Santiago
$586 Roundtrip, found 1 day ago
$586
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Nov 10 from Santo Domingo to Santiago, returning Sun, Nov 16, priced at $586 found 1 day ago
Copa
Thu, Nov 20 - Thu, Nov 27
SDQ
Santo Domingo
SCL
Santiago
$610 Roundtrip, found 2 days ago
$610
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Nov 20 from Santo Domingo to Santiago, returning Thu, Nov 27, priced at $610 found 2 days ago
Copa
Thu, Nov 20 - Mon, Dec 1
SDQ
Santo Domingo
SCL
Santiago
$622 Roundtrip, found 3 hours ago
$622
Roundtrip
found 3 hours ago
Select Copa flight, departing Thu, Nov 20 from Santo Domingo to Santiago, returning Mon, Dec 1, priced at $622 found 3 hours ago
Copa
Thu, Nov 20 - Thu, Nov 27
SDQ
Santo Domingo
SCL
Santiago
$634 Roundtrip, found 2 days ago
$634
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Nov 20 from Santo Domingo to Santiago, returning Thu, Nov 27, priced at $634 found 2 days ago
avianca
Thu, Nov 20 - Thu, Nov 27
SDQ
Santo Domingo
SCL
Santiago
$658 Roundtrip, found 2 days ago
$658
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Nov 20 from Santo Domingo to Santiago, returning Thu, Nov 27, priced at $658 found 2 days ago
Aeromexico
Sun, Jan 25 - Fri, Jan 30
SDQ
Santo Domingo
SCL
Santiago
$826 Roundtrip, found 1 day ago
$826
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Sun, Jan 25 from Santo Domingo to Santiago, returning Fri, Jan 30, priced at $826 found 1 day ago
United
Fri, Nov 7 - Mon, Nov 10
SDQ
Santo Domingo
SCL
Santiago
$865 Roundtrip, found 1 day ago
$865
Roundtrip
found 1 day ago
Select United flight, departing Fri, Nov 7 from Santo Domingo to Santiago, returning Mon, Nov 10, priced at $865 found 1 day ago
American Airlines
Wed, Apr 1 - Wed, Apr 8
SDQ
Santo Domingo
SCL
Santiago
$1,611 Roundtrip, just found
$1,611
Roundtrip
just found
Select American Airlines flight, departing Wed, Apr 1 from Santo Domingo to Santiago, returning Wed, Apr 8, priced at $1,611 just found

Find the cheapest month to fly from Santo Domingo (SDQ) to Santiago (SCL)

September is typically the cheapest month to fly

From $446 - $1,019 per traveler.

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $862
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $862
Flights from Santo Domingo (SDQ) to Santiago (SCL)
Origin airport
Las Americas Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, American Airlines, Copa, Delta, United, avianca
Roundtrip price
$538
Distance
3581 mi

Santo Domingo to Santiago Flights

The cheapest times to fly from Santo Domingo to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Santiago are during the month of November. You can find some of the cheapest flights from Santo Domingo to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Santiago

Sunday is one of the best days to book for cheap flights from Santo Domingo to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $345 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL) cost?
Grab a cheap one-way flight from $345 or cheap return flight from $539 from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL)?
November is the cheapest month to fly from SDQ to SCL. Timing your trip outside of the busy season is often the key to finding better fares.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest SDQ to SCL flight.
How many flights per day from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL)?
There are no daily direct flights available from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL). But you can opt for flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from SDQ to SCL?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from SDQ to SCL?
Arajet has the strongest track record for on-time direct flights from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL), with an on-time score of 83%. Use the Expedia App to check your flight schedule before you take off and receive notifications about any trip changes.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL)?
Choose a flight from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL) last-minute?
Booking your ticket from SDQ to SCL just before your getaway is typically more expensive. However, if you're flexible with your departure times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a SDQ to SCL flight and hotel package?
Booking a SDQ to SCL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Select from our wide range of stays and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Arturo Merino Benitez Airport (SCL)?
If you booked your SDQ to SCL flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

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*Available to One Key members.