$528 Cheap Flights from Santander (SDR) to Chicago (ORD)

View $528 flight on Wed, Jun 3, 2026Opens in a new window

Popular airlines from Santander (SDR) to Chicago O'Hare Intl. Airport (ORD)

Cheap Flights from Santander to Chicago (SDR-ORD)

Prices were available within the past 7 days and start at $528 for one-way flights and $682 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$682 Roundtrip, found 6 days ago
$682
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $682 found 6 days ago
Iberia
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$691 Roundtrip, found 6 days ago
$691
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $691 found 6 days ago
Iberia
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$710 Roundtrip, found 6 days ago
$710
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $710 found 6 days ago
Iberia
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$718 Roundtrip, found 6 days ago
$718
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $718 found 6 days ago
Iberia
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$737 Roundtrip, found 6 days ago
$737
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $737 found 6 days ago
Iberia
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$872 Roundtrip, found 6 days ago
$872
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $872 found 6 days ago
Finnair
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$880 Roundtrip, found 6 days ago
$880
Roundtrip
found 6 days ago
Select Finnair flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $880 found 6 days ago
Iberia
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$892 Roundtrip, found 6 days ago
$892
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $892 found 6 days ago
Iberia
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$894 Roundtrip, found 6 days ago
$894
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $894 found 6 days ago
Finnair
Thu, Dec 11 - Mon, Dec 15
SDR
Santander
ORD
Chicago
$899 Roundtrip, found 6 days ago
$899
Roundtrip
found 6 days ago
Select Finnair flight, departing Thu, Dec 11 from Santander to Chicago, returning Mon, Dec 15, priced at $899 found 6 days ago

Frequently asked questions

How much does a flight from Santander Airport (SDR) to O'Hare Intl. Airport (ORD) cost?
Secure a cheap one-way flight from $528 or cheap return flight from $682 from Santander Airport (SDR) to O'Hare Intl. Airport (ORD) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Santander Airport (SDR) to O'Hare Intl. Airport (ORD)?
December is the most affordable month to fly from SDR to ORD. Timing your trip outside of the busy season is often the key to finding better fares.
What is the cheapest airline that flies from Santander Airport (SDR) to O'Hare Intl. Airport (ORD)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from SDR to ORD. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Santander Airport (SDR) to O'Hare Intl. Airport (ORD)?
You'll have to take a flight with a layover when traveling from Santander Airport (SDR) to O'Hare Intl. Airport (ORD). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from SDR to ORD?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change based on a range of factors, such as the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Santander Airport (SDR) to O'Hare Intl. Airport (ORD)?
To arrive at O'Hare Intl. Airport (ORD) without delays, select a flight that takes off from Santander Airport (SDR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Santander Airport (SDR) to O'Hare Intl. Airport (ORD) last-minute?
Booking your ticket from SDR to ORD shortly before your getaway is typically more expensive. But if you're flexible with your travel dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a SDR to ORD flight and hotel package?
Compared with arranging hotels and flights separately, booking a SDR to ORD flight and hotel package with Expedia could lead to significant savings. Better still, managing everything in one place takes the hassle out of travel planning. Just secure your flights and select from our wide range of hotels, then customize your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Santander Airport (SDR) to O'Hare Intl. Airport (ORD)?
In most instances, you can modify or cancel your SDR to ORD flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you want more information, go to our Customer Service portal.

Travel information

Origin airport
Santander
Destination airport
O'Hare Intl.
Roundtrip price
$682
Distance
4074 mi

Book with confidence

Santander to Chicago Flights

The cheapest times to fly from Santander to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santander to Chicago are during the month of December. You can find some of the cheapest flights from Santander to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santander to Chicago

Sunday is one of the best days to book for cheap flights from Santander to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santander to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santander to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $528 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santander to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santander to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santander to Chicago Flights

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*Available to One Key members.