$139 Cheap Flights from St. Louis (STL) to Guayaquil (GYE)

View $139 flight on Sun, Dec 7, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE)

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Cheap Flights from St. Louis to Guayaquil (STL-GYE)

Prices were available within the past 7 days and start at $139 for one-way flights and $581 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Oct 16 - Wed, Oct 22
STL
St. Louis
GYE
Guayaquil
$581 Roundtrip, found 21 hours ago
$581
Roundtrip
found 21 hours ago
Select United flight, departing Thu, Oct 16 from St. Louis to Guayaquil, returning Wed, Oct 22, priced at $581 found 21 hours ago
United
Tue, Jan 20 - Tue, Feb 3
STL
St. Louis
GYE
Guayaquil
$587 Roundtrip, found 3 hours ago
$587
Roundtrip
found 3 hours ago
Select United flight, departing Tue, Jan 20 from St. Louis to Guayaquil, returning Tue, Feb 3, priced at $587 found 3 hours ago
Delta
Sun, Jan 25 - Thu, Feb 5
STL
St. Louis
GYE
Guayaquil
$589 Roundtrip, found 3 hours ago
$589
Roundtrip
found 3 hours ago
Select Delta flight, departing Sun, Jan 25 from St. Louis to Guayaquil, returning Thu, Feb 5, priced at $589 found 3 hours ago
Delta
Wed, Nov 26 - Tue, Dec 9
STL
St. Louis
GYE
Guayaquil
$593 Roundtrip, found 4 days ago
$593
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Nov 26 from St. Louis to Guayaquil, returning Tue, Dec 9, priced at $593 found 4 days ago
Delta
Wed, Dec 3 - Tue, Dec 16
STL
St. Louis
GYE
Guayaquil
$593 Roundtrip, found 3 hours ago
$593
Roundtrip
found 3 hours ago
Select Delta flight, departing Wed, Dec 3 from St. Louis to Guayaquil, returning Tue, Dec 16, priced at $593 found 3 hours ago
Delta
Wed, Dec 3 - Sun, Dec 14
STL
St. Louis
GYE
Guayaquil
$594 Roundtrip, found 5 days ago
$594
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Dec 3 from St. Louis to Guayaquil, returning Sun, Dec 14, priced at $594 found 5 days ago
United
Tue, Nov 25 - Sun, Dec 7
STL
St. Louis
GYE
Guayaquil
$597 Roundtrip, found 4 days ago
$597
Roundtrip
found 4 days ago
Select United flight, departing Tue, Nov 25 from St. Louis to Guayaquil, returning Sun, Dec 7, priced at $597 found 4 days ago
American Airlines
Thu, Mar 5 - Thu, Mar 12
STL
St. Louis
GYE
Guayaquil
$653 Roundtrip, found 22 hours ago
$653
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Thu, Mar 5 from St. Louis to Guayaquil, returning Thu, Mar 12, priced at $653 found 22 hours ago
LATAM Airlines Group
Tue, Nov 11 - Sun, Nov 23
STL
St. Louis
GYE
Guayaquil
$683 Roundtrip, found 2 days ago
$683
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Nov 11 from St. Louis to Guayaquil, returning Sun, Nov 23, priced at $683 found 2 days ago
avianca
Mon, Jan 12 - Sat, Jan 31
STL
St. Louis
GYE
Guayaquil
$881 Roundtrip, found 3 hours ago
$881
Roundtrip
found 3 hours ago
Select avianca flight, departing Mon, Jan 12 from St. Louis to Guayaquil, returning Sat, Jan 31, priced at $881 found 3 hours ago

Alternative airports near Guayaquil

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Joaquin de Olmedo Intl. GYE. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $581
GYE
Jose Joaquin de Olmedo Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $581

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE) cost?
Secure a cheap one-way flight from $139 or cheap return flight from $581 from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
The cheapest month to fly from STL to GYE is October, when demand is low. Off-peak season is typically when better flight deals are available between these airports.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest STL to GYE flight.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Direct flights from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from STL to GYE?
Typically you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
To land at Jose Joaquin de Olmedo Intl. Airport (GYE) without delays, opt for a flight that leaves from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE) last-minute?
Waiting until just before your departure to book a ticket from STL to GYE often results in higher prices. While you might find some last-minute deals, they're not always guaranteed. Keep your travel schedule open to boost your chances of getting a bargain.
Is it cheaper to book a STL to GYE flight and hotel package?
You'll typically save money by booking a STL to GYE flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've selected your preferred accommodations and flights, consider adding extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
In most instances, you can reschedule or cancel your STL to GYE flight. However, there may be additional fees, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you'd like more details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Jose Joaquin de Olmedo Intl.
Airlines serving
American Airlines, Delta, LATAM Airlines Group, United
Roundtrip price
$581
Distance
2902 mi

Book with confidence

Book with confidence

St. Louis to Guayaquil Flights

The cheapest times to fly from St. Louis to Guayaquil

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Guayaquil are during the month of October. You can find some of the cheapest flights from St. Louis to Guayaquil with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Guayaquil

Sunday is one of the best days to book for cheap flights from St. Louis to Guayaquil: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Guayaquil

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Guayaquil in 2025. You can also book with separate airlines for your outbound and return journeys, from $139 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Guayaquil flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Guayaquil airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Guayaquil Flights

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*Available to One Key members.