$239 Cheap Flights from St. Louis (STL) to Roanoke (ROA)

View $239 flight on Mon, Jan 19, 2026Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Roanoke Regional Airport (ROA)

Cheap Flights from St. Louis to Roanoke (STL-ROA)

Prices were available within the past 7 days and start at $239 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Dec 10 - Sat, Dec 13
STL
St. Louis
ROA
Roanoke
$249 Roundtrip, found 2 hours ago
$249
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Dec 10 from St. Louis to Roanoke, returning Sat, Dec 13, priced at $249 found 2 hours ago
United
Sun, Nov 23 - Fri, Nov 28
STL
St. Louis
ROA
Roanoke
$255 Roundtrip, found 3 days ago
$255
Roundtrip
found 3 days ago
Select United flight, departing Sun, Nov 23 from St. Louis to Roanoke, returning Fri, Nov 28, priced at $255 found 3 days ago
United
Sun, Nov 23 - Fri, Nov 28
STL
St. Louis
ROA
Roanoke
$262 Roundtrip, found 3 days ago
$262
Roundtrip
found 3 days ago
Select United flight, departing Sun, Nov 23 from St. Louis to Roanoke, returning Fri, Nov 28, priced at $262 found 3 days ago
United
Sun, Nov 23 - Fri, Nov 28
STL
St. Louis
ROA
Roanoke
$263 Roundtrip, found 3 days ago
$263
Roundtrip
found 3 days ago
Select United flight, departing Sun, Nov 23 from St. Louis to Roanoke, returning Fri, Nov 28, priced at $263 found 3 days ago
Delta
Wed, Nov 19 - Thu, Nov 27
STL
St. Louis
ROA
Roanoke
$264 Roundtrip, found 17 hours ago
$264
Roundtrip
found 17 hours ago
Select Delta flight, departing Wed, Nov 19 from St. Louis to Roanoke, returning Thu, Nov 27, priced at $264 found 17 hours ago
Delta
Thu, Nov 27 - Fri, Dec 12
STL
St. Louis
ROA
Roanoke
$274 Roundtrip, found 10 hours ago
$274
Roundtrip
found 10 hours ago
Select Delta flight, departing Thu, Nov 27 from St. Louis to Roanoke, returning Fri, Dec 12, priced at $274 found 10 hours ago
United
Fri, Dec 5 - Wed, Dec 10
STL
St. Louis
ROA
Roanoke
$275 Roundtrip, found 3 days ago
$275
Roundtrip
found 3 days ago
Select United flight, departing Fri, Dec 5 from St. Louis to Roanoke, returning Wed, Dec 10, priced at $275 found 3 days ago
American Airlines
Sat, Nov 15 - Wed, Nov 19
STL
St. Louis
ROA
Roanoke
$279 Roundtrip, found 12 hours ago
$279
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Nov 15 from St. Louis to Roanoke, returning Wed, Nov 19, priced at $279 found 12 hours ago
Delta
Wed, Nov 19 - Sun, Nov 23
STL
St. Louis
ROA
Roanoke
$289 Roundtrip, found 17 hours ago
$289
Roundtrip
found 17 hours ago
Select Delta flight, departing Wed, Nov 19 from St. Louis to Roanoke, returning Sun, Nov 23, priced at $289 found 17 hours ago
United
Wed, Feb 4 - Sat, Feb 7
STL
St. Louis
ROA
Roanoke
$290 Roundtrip, found 4 days ago
$290
Roundtrip
found 4 days ago
Select United flight, departing Wed, Feb 4 from St. Louis to Roanoke, returning Sat, Feb 7, priced at $290 found 4 days ago

Find the cheapest month to fly from St. Louis (STL) to Roanoke (ROA)

April is typically the cheapest month to fly

From $198 - $494 per traveler.

Alternative airports near Roanoke

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Roanoke Regional ROA. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $264
ROA
Roanoke Regional
CheapestClosest
Average driving time to city center9 min
Flights from $264

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA) cost?
Grab a cheap one-way flight from $239 or cheap return flight from $249 from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA)?
Planning your trip for December is a great way to save, as it's the cheapest month for flights between STL and ROA. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll fly you from STL to ROA. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA)?
There aren't any daily nonstop flights available from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from STL to ROA?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* But this can change depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA)?
To touch down at Roanoke Regional Airport (ROA) without delays, pick a flight that leaves from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA) last-minute?
Booking your plane ticket from STL to ROA right before your journey is typically more expensive. But if you're flexible with your itinerary, you could bag a cheap last-minute fare.
Is it cheaper to book a STL to ROA flight and hotel package?
Compared with arranging flights and hotels separately, booking a STL to ROA flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place takes the hassle out of travel planning. Just pick your flights and select from our wide range of stays, then customize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA)?
In most instances, you can modify or cancel your STL to ROA flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you'd like further details, head to our Customer Service portal.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Roanoke Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
573 mi

Book with confidence

St. Louis to Roanoke Flights

The cheapest times to fly from St. Louis to Roanoke

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Roanoke are during the month of December. You can find some of the cheapest flights from St. Louis to Roanoke with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Roanoke

Sunday is one of the best days to book for cheap flights from St. Louis to Roanoke: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Roanoke

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Roanoke in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Roanoke flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Roanoke airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Roanoke Flights

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*Available to One Key members.