Cheap Flights from Tampa (TPA) to St. Louis (CPS)

Popular airlines from Tampa Intl. Airport (TPA) to St. Louis, MO (CPS-St. Louis Downtown)

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $144
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $144

Frequently asked questions

How much does a flight from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS) cost?
Snag a cheap one-way flight or cheap return flight from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS)?
is the cheapest month to fly from TPA to CPS. Avoiding peak travel times is often the key to better flight prices.
What is the cheapest airline that flies from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS)?
To find the cheapest airline that'll fly you from TPA to CPS, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS)?
Nonstop flights from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TPA to CPS?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can vary depending on various factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS)?
To avoid potential delays on the Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS) route, travel before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for East St. Louis from Tampa Intl. Airport (TPA)?
Explore your flight options from Tampa Intl. Airport (TPA) to Lambert-St. Louis Intl. Airport (STL). This is the only East St. Louis airport you can fly into if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS) last-minute?
Last-minute bookings from TPA to CPS are typically more expensive. To secure the best rates, start searching for flights well ahead of time. That said, if you can play around with your travel dates, you may find a cheap ticket right before your trip.
Is it cheaper to book a TPA to CPS flight and hotel package?
You can save money by securing a TPA to CPS flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've selected your ideal accommodations and flights, consider adding extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Tampa Intl. Airport (TPA) to St. Louis Downtown Airport (CPS)?
If you booked your TPA to CPS flight within the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Travel information

Origin airport
Tampa Intl.
Destination airport
St. Louis Downtown
Distance
853 mi

Book with confidence

Tampa to St. Louis Flights

The cheapest times to fly from Tampa to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tampa to St. Louis are during the month of . You can find some of the cheapest flights from Tampa to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tampa to St. Louis

Sunday is one of the best days to book for cheap flights from Tampa to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tampa to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tampa to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tampa to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tampa to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Tampa to St. Louis Flights

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*Available to One Key members.