$158 Cheap Flights from Tupelo (TUP) to Houston (HOU)

View $158 flight on Wed, Oct 22, 2025Opens in a new window

Popular airlines from Tupelo, MS (TUP-Tupelo Regional) to Houston William Hobby Airport (HOU)

Cheap Flights from Tupelo to Houston (TUP-HOU)

Prices were available within the past 7 days and start at $158 for one-way flights and $416 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Contour Airlines
Tue, Dec 23 - Tue, Dec 30
TUP
Tupelo
HOU
Houston
$416 Roundtrip, found 2 days ago
$416
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Tue, Dec 23 from Tupelo to Houston, returning Tue, Dec 30, priced at $416 found 2 days ago

Alternative airports near Houston

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to George Bush Intercontinental IAH. Cheapest option available. Average driving time to city center is 24 minutes. Flights from $430
IAH
George Bush Intercontinental
Cheapest
Average driving time to city center24 min
Flights from $430
Flights from Tupelo (TUP) to Houston (HOU)
Origin airport
Tupelo Regional
Destination airport
William P. Hobby
Roundtrip price
$416
Distance
496 mi

Tupelo to Houston Flights

The cheapest times to fly from Tupelo to Houston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tupelo to Houston are during the month of December. You can find some of the cheapest flights from Tupelo to Houston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tupelo to Houston

Sunday is one of the best days to book for cheap flights from Tupelo to Houston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tupelo to Houston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tupelo to Houston in 2025. You can also book with separate airlines for your outbound and return journeys, from $158 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tupelo to Houston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tupelo to Houston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU) cost?
Get a cheap one-way flight from $158 or cheap return flight from $416 from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU)?
December is the most affordable month to fly from TUP to HOU. Timing your trip outside of the busy season is often the key to better flight prices.
What is the cheapest airline that flies from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest TUP to HOU flight.
How many flights per day from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU)?
You'll have to take a flight with a layover if you're traveling from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from TUP to HOU?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU)?
To avoid potential delays on the Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU) route, aim to fly before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU) last-minute?
Booking your ticket from TUP to HOU right before your journey is generally more expensive. But if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a TUP to HOU flight and hotel package?
Compared with arranging flights and hotels separately, booking a TUP to HOU flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one place will take the stress out of planning your trip. Simply pick your flights and choose from our wide range of hotels, then customize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Tupelo Regional Airport (TUP) to William P. Hobby Airport (HOU)?
You can usually reschedule or cancel your TUP to HOU flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.