$159 Cheap Flights from Knoxville (TYS) to Memphis (MEM)

View $159 flight on Tue, Dec 2, 2025Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Memphis International Airport (MEM)

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Cheap Flights from Knoxville to Memphis (TYS-MEM)

Prices were available within the past 7 days and start at $159 for one-way flights and $317 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jan 20 - Tue, Feb 3
TYS
Knoxville
MEM
Memphis
$317 Roundtrip, found 4 days ago
$317
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jan 20 from Knoxville to Memphis, returning Tue, Feb 3, priced at $317 found 4 days ago
Delta
Wed, Feb 4 - Tue, Feb 17
TYS
Knoxville
MEM
Memphis
$317 Roundtrip, found 1 hour ago
$317
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Feb 4 from Knoxville to Memphis, returning Tue, Feb 17, priced at $317 found 1 hour ago
Delta
Tue, Jan 20 - Tue, Feb 3
TYS
Knoxville
MEM
Memphis
$319 Roundtrip, found 4 days ago
$319
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Jan 20 from Knoxville to Memphis, returning Tue, Feb 3, priced at $319 found 4 days ago
United
Fri, Jan 23 - Tue, Jan 27
TYS
Knoxville
MEM
Memphis
$327 Roundtrip, found 14 hours ago
$327
Roundtrip
found 14 hours ago
Select United flight, departing Fri, Jan 23 from Knoxville to Memphis, returning Tue, Jan 27, priced at $327 found 14 hours ago
United
Fri, Jan 23 - Tue, Jan 27
TYS
Knoxville
MEM
Memphis
$331 Roundtrip, found 14 hours ago
$331
Roundtrip
found 14 hours ago
Select United flight, departing Fri, Jan 23 from Knoxville to Memphis, returning Tue, Jan 27, priced at $331 found 14 hours ago
American Airlines
Wed, Dec 10 - Mon, Dec 15
TYS
Knoxville
MEM
Memphis
$332 Roundtrip, found 4 days ago
$332
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 10 from Knoxville to Memphis, returning Mon, Dec 15, priced at $332 found 4 days ago
Southwest Airlines
Wed, Mar 11 - Thu, Mar 12
TYS
Knoxville
MEM
Memphis
$337 Roundtrip, found 18 hours ago
$337
Roundtrip
found 18 hours ago
Select Southwest Airlines flight, departing Wed, Mar 11 from Knoxville to Memphis, returning Thu, Mar 12, priced at $337 found 18 hours ago
Delta
Wed, Jun 10 - Thu, Jun 11
TYS
Knoxville
MEM
Memphis
$340 Roundtrip, found 14 hours ago
$340
Roundtrip
found 14 hours ago
Select Delta flight, departing Wed, Jun 10 from Knoxville to Memphis, returning Thu, Jun 11, priced at $340 found 14 hours ago
American Airlines
Fri, Jan 23 - Tue, Jan 27
TYS
Knoxville
MEM
Memphis
$341 Roundtrip, found 14 hours ago
$341
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Fri, Jan 23 from Knoxville to Memphis, returning Tue, Jan 27, priced at $341 found 14 hours ago
Frontier Airlines
Sun, Nov 2 - Mon, Nov 24
TYS
Knoxville
MEM
Memphis
$560 Roundtrip, found 8 hours ago
$560
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Sun, Nov 2 from Knoxville to Memphis, returning Mon, Nov 24, priced at $560 found 8 hours ago

Find the cheapest month to fly from Knoxville (TYS) to Memphis (MEM)

May is typically the cheapest month to fly

From $198 - $487 per traveler.

Alternative airports near Memphis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Memphis Intl. MEM. Cheapest and Closest option available. Average driving time to city center is 15 minutes. Flights from $441
MEM
Memphis Intl.
CheapestClosest
Average driving time to city center15 min
Flights from $441

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM) cost?
Secure a cheap one-way flight from $159 or cheap return flight from $317 from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM)?
Traveling in January can help you save, as it's the cheapest month for flights between TYS and MEM. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM)?
To find the cheapest airline flying from TYS to MEM, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM)?
Nonstop flights from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYS to MEM?
Typically you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM)?
Select a flight from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM) that leaves before 3 PM to reduce the risk of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM) last-minute?
Last-minute fares from TYS to MEM are typically more expensive. To lock in the cheapest rates, start looking for flights as early as possible. That being said, if your travel plans are flexible, you may land a cheap fare right before your trip.
Is it cheaper to book a TYS to MEM flight and hotel package?
You'll generally save money by booking a TYS to MEM flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. Once you've chosen your preferred accommodations and flights, consider adding extras including tours, activities and car rentals.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Memphis Intl. Airport (MEM)?
If you reserved your TYS to MEM flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the fare type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

Travel information

0
Origin airport
McGhee Tyson
Destination airport
Memphis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$316
Distance
341 mi

Book with confidence

Knoxville to Memphis Flights

The cheapest times to fly from Knoxville to Memphis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Memphis are during the month of January. You can find some of the cheapest flights from Knoxville to Memphis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Memphis

Sunday is one of the best days to book for cheap flights from Knoxville to Memphis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Memphis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Memphis in 2025. You can also book with separate airlines for your outbound and return journeys, from $159 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Memphis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Memphis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Memphis Flights

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*Available to One Key members.