Title: Southern Minnesota Pet-friendly Vacations 2026 | Expedia.com ![](https://images.trvl-media.com/place/10435/7473d16d-2521-40dd-9755-27c6b94cade6.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Southern Minnesota Pet-friendly Vacations ## Book a Pet-friendly Hotel + Flight or Car together to unlock savings Photo by Kirsten - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## 4 Night Pet-friendly vacations in Southern Minnesota Price found within the past 48 hours. Click for updated prices. ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S $395 per person Apr 6 - Apr 10 found 18 hours ago Roundtrip flight included Boston (BOS) to Rochester (RST) 7.2/10 Good! (1,015 reviews) For what we paid, this was a very good hotel. The baby pool was perfect for my 2 year old granddaughter. The pools were both heated, which was great! The breakfast was good. Staff from the front desk to the guy in the breakfast room, to the guys cleaning all of the time were very, very kind and friendly!! Will stay again for sure! Reviewed on Feb 10, 2026 ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Kahler Grand Hotel Downtown Rochester $560 per person Apr 6 - Apr 10 found 18 hours ago Roundtrip flight included Boston (BOS) to Rochester (RST) 8.2/10 Very Good! (1,746 reviews) Clean, quiet, wonderful front desk staff, close to Mayo. Reviewed on Feb 8, 2026 ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Kahler Inn and Suites - Mayo Clinic Area Downtown Rochester $521 per person Apr 6 - Apr 10 found 18 hours ago Roundtrip flight included Boston (BOS) to Rochester (RST) 8/10 Very Good! (1,495 reviews) The room was comfortable, the bedding, nice. The hotel was quiet at night, but there's massive construction going on in every direction, from which the noise starts at 7:30am. Every hotel in the area would be the same for noise. Breakfast was good except the pancakes were tough like shoe leather, but everything else 5 stars. The location was 10 stars! We were directly across the street from the Mayo Clinic. Parking was not a problem despite construction. The only two things for improvement are: There were only 2 outlet plugs between the beds, and none on the walls nearby. This is a challenge for charging phones, CPAPs, laptop, etc. There should be wall outlets nearby. Not everyone can take showers, and the tub was disgusting. The upper shower was clean, but the tub and lower surround were covered in a scummy film. Yuck! There's no excuse for not cleaning those areas. Reviewed on Feb 6, 2026 Don't see what you're looking for? See all available trips from Columbus to Southern Minnesota [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-10/2026-03-17/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=MSP&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Top Pet-friendly Southern Minnesota Hotels ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 101 11TH Avenue SW Rochester MN - 17 min walk from Mayo Clinic This hotel is pet-friendly, allowing dogs with an additional fee. If you're going for a walk during your stay, swing by nearby Mayo Park. 9.2/10 Wonderful! (993 reviews) The room was very clean and all of the staff were very helpful! Reviewed on Feb 10, 2026 [](https://expedia.com/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Aspen Suites 1211 2nd Street Rochester MN - 21 min walk from Mayo Clinic This pet-friendly, city-center hotel welcomes dogs for an additional fee. Nearby Mayo Park is a good place to stretch your legs if you need a walk. 9/10 Wonderful! (720 reviews) Everybody was polite. Morning breakfast was similar to other places I have stayed. In the afternoon they have light foods that were also complimentary. Hallways are tight coming off elevator. Reviewed on Feb 8, 2026 [](https://expedia.com/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt House Rochester/Mayo Clinic Area 110 Civic Center Drive NW Rochester MN - 7 min walk from Mayo Clinic Dogs and cats are welcome (fees apply) at this pet-friendly, city-center hotel. If you'd like to stretch your legs, look no further than nearby Silver Lake ... 9/10 Wonderful! (1,004 reviews) Nice spacious room Reviewed on Jan 29, 2026 [](https://expedia.com/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) [See all 1,200 properties in Southern Minnesota](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6059950) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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