Title: Southern Minnesota Pet-friendly Vacations 2026 | Expedia.com ![](https://images.trvl-media.com/place/10435/7473d16d-2521-40dd-9755-27c6b94cade6.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Southern Minnesota Pet-friendly Vacations ## Book a Pet-friendly Hotel + Flight or Car together to unlock savings Photo by Kirsten - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## 4 Night Pet-friendly vacations in Southern Minnesota Price found within the past 48 hours. Click for updated prices. ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG Downtown Rochester $699 per person Mar 29 - Apr 2 found 1 day ago Roundtrip non-stop flight included Memphis (MEM) to Rochester (RST) 8.8/10 Excellent! (867 reviews) Comfy beds, relatively quiet, great amenities, restaurant/bar is excellent as well. Always stay there when I have to stay in Rochester. Reviewed on Feb 11, 2026 ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Aspen Suites $746 per person Mar 29 - Apr 2 found 1 day ago Roundtrip non-stop flight included Memphis (MEM) to Rochester (RST) 9/10 Wonderful! (677 reviews) It was a very nice stay, everyone was very nice helpful, and on their game. Definitely will be staying again. Great thanks to all. Keep up the great work. Love the location in regards to the hospital. Made our visit to a loved one extremely convenient. I can’t think of anything that needed improvement unless you let us stay free!! Hahaha. Great job !!! Reviewed on Feb 12, 2026 ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Kahler Grand Hotel Downtown Rochester $781 per person Mar 29 - Apr 2 found 1 day ago Roundtrip non-stop flight included Memphis (MEM) to Rochester (RST) 8.2/10 Very Good! (1,746 reviews) Great hotel very clean and convenient it’s attached to Mayo Clinic made all the appointments easy to get too since it’s literally a few steps into Mayo. This was our second time staying here and we definitely will again. Reviewed on Feb 15, 2026 Don't see what you're looking for? See all available trips from Columbus to Southern Minnesota [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-15/2026-03-22/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=MSP&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Top Pet-friendly Southern Minnesota Hotels ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 101 11TH Avenue SW Rochester MN - 17 min walk from Mayo Clinic This hotel is pet-friendly, allowing dogs with an additional fee. If you're going for a walk during your stay, swing by nearby Mayo Park. 9.2/10 Wonderful! (993 reviews) The room was very clean and all of the staff were very helpful! Reviewed on Feb 10, 2026 [](https://expedia.com/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Aspen Suites 1211 2nd Street Rochester MN - 21 min walk from Mayo Clinic This pet-friendly, city-center hotel welcomes dogs for an additional fee. Nearby Mayo Park is a good place to stretch your legs if you need a walk. 9/10 Wonderful! (720 reviews) Everybody was polite. Morning breakfast was similar to other places I have stayed. In the afternoon they have light foods that were also complimentary. Hallways are tight coming off elevator. Reviewed on Feb 8, 2026 [](https://expedia.com/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt House Rochester/Mayo Clinic Area 110 Civic Center Drive NW Rochester MN - 7 min walk from Mayo Clinic Dogs and cats are welcome (fees apply) at this pet-friendly, city-center hotel. If you'd like to stretch your legs, look no further than nearby Silver Lake ... 9/10 Wonderful! (1,006 reviews) The room was clean the staff was friendly and the breakfast was very good. We are all ready planning to go back. Reviewed on Feb 9, 2026 [](https://expedia.com/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) [See all 1,200 properties in Southern Minnesota](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6059950) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app