Title: The Best 2 Star Hotels in Depew, NY from $56 | Expedia.com [Depew Travel Guide](https://expedia.com/Depew.dx6338362)[Hotels in Depew](https://expedia.com/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.com/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.com/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.com/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Car Rentals in Depew](https://expedia.com/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.com/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Depew 2 Star Hotels Tonight [Feb 16 - Feb 17](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-02-16&endDate=2026-02-17&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 17 - Feb 18](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-02-17&endDate=2026-02-18&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6338362&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Depew 2-star hotels ![Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Non Smoking (2 Double Beds & Sofa Bed) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/278a83c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/d35175de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Buffalo Airport [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) Buffalo 8.0/10 Very Good (1,988 reviews) "Nice hotel" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Nilanjan $71 nightly $80 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/47e39417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/bdc29a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/e4b647bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 9:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/83cfb229.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Buffalo - Amherst, NY [](https://www.expedia.com/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) Buffalo 9.4/10 Exceptional (2,009 reviews) "Very clean, friendly staff, breakfast was delicious, loved the variety and quality. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert $107 nightly $122 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/8ad6842a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/dea488a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/73118da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/6f9be9c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CenterWay Hotel Tonawanda [](https://www.expedia.com/Buffalo-Hotels-CenterWay-Hotel-Tonawanda.h76371.Hotel-Information) Tonawanda 7.8/10 Good (1,003 reviews) "Another great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KURT $70 nightly $80 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-CenterWay-Hotel-Tonawanda.h76371.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/a305e7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/ea0d463b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/2685a465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Grand Island - Niagara Falls by IHG [](https://www.expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) Grand Island 8.8/10 Excellent (1,684 reviews) "Great stay, friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian $71 nightly $80 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/f9a47442.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/b2330a35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/00c812b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/a56cf142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information) Downtown Buffalo 8.6/10 Excellent (1,003 reviews) "Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph $104 nightly $121 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/139ee991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/2a472ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6:30 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/b33f35a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/295249d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Near Walden Galleria Mall [](https://www.expedia.com/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) Buffalo 8.0/10 Very Good (1,005 reviews) "Our room was clean, the staff and facility were very helpful and nice, and our dog enjoyed the stay as well!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin $84 nightly $96 total Feb 18 - Feb 19 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/6e825f18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Television](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/7e380454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/e8171ea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/072093a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Amherst, NY - Buffalo [](https://www.expedia.com/Buffalo-Hotels-Motel-6-Amherst.h42198.Hotel-Information) Buffalo 6.4/10 (1,001 reviews) "Clean and roomy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jackson $60 nightly $68 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Motel-6-Amherst.h42198.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/2db1a2f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/764d9cbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/a57eee4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/1f31d14d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn University [](https://www.expedia.com/Buffalo-Hotels-Comfort-Inn-University.h66581.Hotel-Information) Buffalo 8.2/10 Very Good (1,249 reviews) "Clean comfortable good breakfast and reasonable price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy $90 nightly $103 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Comfort-Inn-University.h66581.Hotel-Information) ![Deluxe Room, 2 Double Beds (Smoke Free) | 1 bedroom, desk, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/dec8cb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/816/760d0b9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/816/6d5f06be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/d1c4663a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo - Niagara Airport [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) Bowmansville 7.2/10 Good (1,000 reviews) "Room was very clean, staff very courteous " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sonia $49 nightly $56 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8561/98479979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, 2 Double Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/8600/8561/947fa4bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8561/e2191a46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8600/8561/9ad12db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Suites - Buffalo - Airport [](https://www.expedia.com/Buffalo-Hotels-Extended-Stay-America-Suites-Buffalo-Airport.h8561.Hotel-Information) Buffalo 7.0/10 Good (1,028 reviews) "Would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yolanda $69 nightly $78 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Extended-Stay-America-Suites-Buffalo-Airport.h8561.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/46db5598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/73648063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/c135a4a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/1726aaa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Summit Inn [](https://www.expedia.com/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) Niagara Falls 8.6/10 Excellent (1,432 reviews) "Yes very nice breakfast set up ! Great place we will be back again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana $71 nightly $81 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/d64d0a69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/0040d6bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/327eb062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/4a83a7cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Cheektowaga North East by IHG [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Cheektowaga-North-East.h8130557.Hotel-Information) Buffalo 8.6/10 Excellent (1,248 reviews) "Always a great place to stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Dale $98 nightly $112 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Cheektowaga-North-East.h8130557.Hotel-Information) ![In-room safe, desk, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/24b9dd25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/a8136605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/8659347d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/056e4b17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo – Hamburg/ I-90 [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Hamburg-I-90.h17404.Hotel-Information) Hamburg 5.8/10 (1,000 reviews) "Not the best. Convenient location if going to Bills gane" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth $68 nightly $77 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Hamburg-I-90.h17404.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/a429a676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/dbce5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/6c12c2ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/08466402.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Amherst - Buffalo North near University [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn.h126836.Hotel-Information) Buffalo 8.8/10 Excellent (1,144 reviews) "Easy check-in. Pool and hot tub were great! Friendly staff and clean rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa $89 nightly $102 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Sleep-Inn.h126836.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/1a5b867a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/a19fbffa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/93ad4fec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/14d1fc73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Buffalo South I-90, NY [](https://www.expedia.com/Buffalo-Hotels-Country-Inn-Suites-By-Radisson.h5313625.Hotel-Information) Buffalo 8.2/10 Very Good (1,308 reviews) "Clean, nice property, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lindsay $121 nightly $137 total Mar 12 - Mar 13 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Country-Inn-Suites-By-Radisson.h5313625.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/10000/2200/2196/e531e69e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2200/2196/bb96b384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/10000/2200/2196/7c123407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2200/2196/w2990h2005x0y16-ce4bee0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairbridge Inn Express Buffalo Airport Williamsville [](https://www.expedia.com/Buffalo-Hotels-FairBridge-Inn-Express-Buffalo-Airport-Williamsville.h2196.Hotel-Information) Buffalo 4.6/10 (1,007 reviews) "Always have a great time when I go my great getaway spot never no issues friendly staff see y'all again real soon have a great day 💋" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawntel $56 nightly $64 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-FairBridge-Inn-Express-Buffalo-Airport-Williamsville.h2196.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/30000/23200/23120/2bb1d8bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23200/23120/3e56ff70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Kitchenette (with Sofabed) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/23200/23120/5d80963b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/23200/23120/d148ff08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Galleria Inn & Suites [](https://www.expedia.com/Buffalo-Hotels-Best-Western-Plus-Galleria-Inn-Suites.h23120.Hotel-Information) Buffalo 6.6/10 (1,001 reviews) "Nice place " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Antonio $80 nightly $91 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Best-Western-Plus-Galleria-Inn-Suites.h23120.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2850000/2841800/2841764/e564d189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/3000000/2850000/2841800/2841764/8fb47646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2850000/2841800/2841764/fd480a3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2850000/2841800/2841764/4074f60b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Buffalo Airport [](https://www.expedia.com/Buffalo-Hotels-Fairfield-Inn-Suites-By-Marriott-Buffalo-Airport.h2841764.Hotel-Information) Buffalo 8.6/10 Excellent (1,000 reviews) "The room was spotless and the staff was very accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon $105 nightly $120 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Fairfield-Inn-Suites-By-Marriott-Buffalo-Airport.h2841764.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/22000000/21330000/21330000/21329922/9b6ff48b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21330000/21330000/21329922/08bebab4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21330000/21330000/21329922/1899cc3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Hearing) | Blackout drapes, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/22000000/21330000/21330000/21329922/41e7c029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Williamsville Buffalo Airport [](https://www.expedia.com/Buffalo-Hotels-Tru-By-Hilton-Williamsville-Buffalo-Airport.h21329922.Hotel-Information) Buffalo 8.8/10 Excellent (1,003 reviews) "Cleanliness, quiet and great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Delci Maria $98 nightly $111 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Tru-By-Hilton-Williamsville-Buffalo-Airport.h21329922.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/b3c0a8a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking (with Sofabed) | Individually furnished, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/1eafede6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/4eac0a0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/100000000/99810000/99802700/99802648/7d3bff92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Buffalo Inn & Suites [](https://www.expedia.com/Eva-Hotel.h99802648.Hotel-Information) Buffalo 8.8/10 Excellent (886 reviews) "Staff was extremely friendly and rooms were clean" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Daniel $87 nightly $99 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Eva-Hotel.h99802648.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Depew-Hotels.s20-0-d6338362.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Depew-Hotels.s20-0-d6338362.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Depew. ![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### M Hotel Buffalo 2040 Walden Ave Buffalo NY $99 nightly $113 total Feb 17 - Feb 18 Total with taxes and fees 7.2/10 Good! (2,635 reviews) [](https://expedia.com/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information) ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/90223c0d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Buffalo Airport Hotel 4600 Genesee St Buffalo NY $95 nightly $108 total Mar 2 - Mar 3 Total with taxes and fees 7.8/10 Good! (2,883 reviews) [](https://expedia.com/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Regency Buffalo / Hotel and Conference Center Two Fountain Plaza Buffalo NY $135 nightly $158 total Feb 17 - Feb 18 Total with taxes and fees 8/10 Very Good! (1,743 reviews) [](https://expedia.com/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) Still don't see what you're looking for? [See all properties in Depew.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F17%2F2026&endDate=2%2F18%2F2026®ionId=6338362&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F17%2F2026&endDate=2%2F18%2F2026®ionId=6338362&star=20&star=20&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F17%2F2026&endDate=2%2F18%2F2026®ionId=6338362&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F17%2F2026&endDate=2%2F18%2F2026®ionId=6338362&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F17%2F2026&endDate=2%2F18%2F2026®ionId=6338362&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F17%2F2026&endDate=2%2F18%2F2026®ionId=6338362&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Depew Hotel Reviews ![Motel 6 Amherst, NY - Buffalo](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/df50dbea_y.jpg) ### Motel 6 Amherst, NY - Buffalo 10/10 Excellent "The price was very affordable. The room was simple, but clean. The people at the front counter were extremely helpful." [](https://expedia.com/Buffalo-Hotels-Motel-6-Amherst.h42198.Hotel-Information) ## Find out more about Depew When you've got to get away to a new or favorite destination without breaking the bank, Depew awaits with top 2 Star hotels and a change of scenery. Discover a new favorite coffee shop or hiking trail nearby and relax, or stay on your feet visiting the top attractions that draw of visitors. You're about to find out why locals and travelers alike love this place. ### The Right Place at the Ideal Price Thanks to several convenient locations and comfortable amenities, you'll find 2 Star Hotel that suits your vacation style. Stay here and be one of the first guests to leave a review and share your thoughts. So, savor the comfort of a well-kept room and attentive hospitality. With our travel deals, the world is wide open to you one hotel at a time, and the jet-setting starts in Depew. ### Book a Stay in a 2-Star Hotel Today Plan your trip to Depew now with Expedia's easy online travel booking and start relaxing before you even leave the house. If you need a break from the crowds, you may find that this region offers just the reprieve you've been looking for. Take advantage of the 2 Star Hotel availability and easy-going atmosphere. ## Frequently asked questions ### How much does it cost to stay in a 2-star hotel in Depew? ### What is the difference between a 2-star Depew hotel and a 3-star hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Reinstein Woods Nature Preserve and Environmental Education Center ](https://www.expedia.com/Reinstein-Woods-Nature-Preserve-And-Environmental-Education-Center-Hotels.0-l553248621561173660-0.Travel-Guide-Filter-Hotels) - [Hotels near Buffalo-Depew Station ](https://www.expedia.com/Buffalo-Depew-Station-Hotels.d6194293.Travel-Guide-Hotels) - [Hotels near Buffalo Niagara Intl. ](https://www.expedia.com/Buffalo-Niagara-Intl-Airport-Hotels.0-aBUF-0.Travel-Guide-Filter-Hotels) - [Hotels near Stiglmeier Park ](https://www.expedia.com/Stiglmeier-Park-Hotels.0-l553248621558133903-0.Travel-Guide-Filter-Hotels) - [Hotels near Lancaster Opera House ](https://www.expedia.com/Lancaster-Opera-House-Hotels.0-l553248621532664862-0.Travel-Guide-Filter-Hotels) - 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