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Find 5 Star Hotels in Depew, NY from $117

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Check availability on Depew 5 Star Hotels

Tonight
Sep 16 - Sep 17
Tomorrow
Sep 17 - Sep 18
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Depew 5-star hotels

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.
A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.
A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

1. Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel
Downtown Buffalo
United States
Reshma Tricia
$278 nightly
$325 total
Oct 11 - Oct 12
Total with taxes and fees
Curtiss Hotel, an Ascend Collection Hotel
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Depew.
The Delavan Hotel & Spa

The Delavan Hotel & Spa

6461 Transit Road Bowmansville NY
$103 nightly
$117 total
Oct 12 - Oct 13
Total with taxes and fees
9/10 Wonderful! (1,001 reviews)
The Delavan Hotel & Spa
The Mansion On Delaware Ave

The Mansion On Delaware Ave

414 Delaware Ave Buffalo NY
$177 nightly
$204 total
Sep 20 - Sep 21
Total with taxes and fees
9.4/10 Exceptional! (1,006 reviews)
The Mansion On Delaware Ave
DoubleTree by Hilton Hotel Buffalo - Amherst

DoubleTree by Hilton Hotel Buffalo - Amherst

10 Flint Rd Buffalo NY
$132 nightly
$150 total
Sep 30 - Oct 1
Total with taxes and fees
7.8/10 Good! (1,003 reviews)
DoubleTree by Hilton Hotel Buffalo - Amherst
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Depew Hotel Reviews

Find out more about Depew

Ready for an incredible adventure? Add further enjoyment on your next trip to Depew by treating yourself to the best of the best when it comes to accommodation. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Depew so popular in the last year. There's no reason to delay a getaway to Depew any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Depew and indulge in the finer things in life for a while. Don't wait any longer!

Get a Great Deal on 5-Star Hotels in Depew

A stay in one of these hotels is bound to be wonderful. High-end restaurants, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. What creature comforts do you want in your lodging? A body scrub that will leave you feeling refreshed and alive? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A rejuvenating facial treatment to help your cares fall away? Want to see for yourself? Plenty of visitors recommend this location.

You won't sleep and order room service the entire time, though. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Depew are the perfect place to rest up after a busy day.

Make Your Escape

The results are in, and Depew 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of Expedia's Depew 5-star hotels today and decompress in the lap of luxury tomorrow.

Frequently asked questions

What are the best 5-star hotels in Depew?
Boasting exceptional amenities and guest services, Expedia customers rate Curtiss Hotel, Ascend Hotel Collection as one of the most popular 5-star hotels in Depew. You'll be immersed in a world of luxury from the moment you enter the lobby.
How much does it cost to stay in a 5-star hotel in Depew?
How much you pay for a 5-star hotel in Depew can vary depending on when you decide to travel and how long you plan to stay, among other factors. Use our price per night filter and other search tools to score the best rate on a high-end stay.
  • Search for the lowest price per night from $117
What makes a hotel 5 stars in Depew?
In Depew, a hotel must provide a specific number of upscale amenities to earn a 5-star rating. These may include on-site gyms, spas and saunas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding service. You can look forward to things like nightly turn-down services, in-room massages and concierge services. Some may also offer extra touches like welcome gifts.

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