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A blue house with a red roof near a river, a white bridge, and a blue walkway.

Find 5 Star Hotels in De Pere, WI from $64

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Check prices for these dates, December 15 – 16, 2026

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Top De Pere Hotel Reviews

Kress Inn, an Ascend Collection Hotel

A spacious living room with a brown leather sofa, a coffee table, and a TV. There is a kitchen area with a microwave and cabinets.

Legacy Hotel Trademark Collection By Wyndham

A multi-story hotel with a prominent 'Legacy Hotel' sign, large windows, and a modern architectural design.

St. Brendan's Inn

A dining area with multiple tables and chairs, large arched windows with colorful stained glass, and hanging light fixtures.

Home2 Suites by Hilton Appleton

An outdoor seating area with a fire pit, yellow and red chairs, and a covered patio with string lights.

Cobblestone Hotel & Suites - De Pere/Green Bay

A modern restaurant with wooden walls and exposed ceilings, featuring multiple dining tables and chairs.

Country Inn & Suites by Radisson, Green Bay North

A building with a stone facade, a covered patio with outdoor seating, and a clear view of the entrance.

Bay Motel

A house with a covered porch, a hanging flower basket, and a garden with various plants.

Hampton Inn Appleton-Fox River Mall Area

A hotel room with a bed, a sofa, a small table, a TV, and a window with a view of buildings.

Fairfield Inn & Suites by Marriott Appleton

A spacious lobby with a wooden ceiling, a stone fireplace, and comfortable seating areas.

CopperLeaf Hotel BW Premier Collection

A hotel room with a large bathtub, a bedside table with a lamp, and artwork on the wall.

Nuks Executive Suites

A view through a window of a river with a bridge, a small building, and a dock.

Holiday Inn Express & Suites Green Bay East by IHG

An indoor swimming pool with clear water, wooden ceiling, and large windows.

My Place Hotel - Green Bay

A hotel with a stone facade, a covered entrance, and a sign reading "my PLACE Hotel".

Cobblestone Hotel & Suites-Little Chute

A spacious lobby with a stone wall, a fireplace, and a seating area with a sofa and chairs.

Find out more about De Pere

Why not demand complete opulence during your trip to De Pere? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made De Pere so popular in the last year. There's no reason to delay a getaway to De Pere any longer. Furthermore, you'll find that these hotels are kept in fantastic condition and provide a fine place to lay your head at night. Reserve one of our 5-star hotels in De Pere and indulge in the finer things in life for a while. What are you waiting for?

5-Star Hotels in De Pere

Don't be afraid to live the high life while you're on vacation, along with the best conditions. Excellent customer care, granite-tiled bathrooms, and deeply relaxing spa offerings are all on offer. You're sure to find exactly the accommodation you need. Additionally, the hotels in this area receive noteworthy marks for customer satisfaction, so you know you'll be well cared for during your getaway. How do you want to relax? A Swedish massage to help your cares fall away? A concierge to help you suggest the next attraction to visit? Fluffy down pillows, lip-smacking main courses, and even spectacular views...these hotels are one-of-a-kind. Don't want to take our word for it? Plenty of visitors recommend this location.

You won't sleep and order room service the entire time, though. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in De Pere are waiting for you to rest up after a busy day.

Your Getaway Starts Today

The results are in, and De Pere 5-star hotels are the place to be when you book your next vacation. These beautiful hotels are highly rated by the guests who stay in them, and you're about to join their ranks. Expedia can help you land a great deal on accommodation. Your great getaway is just a mouse-click away. Select one of the 5-star hotels in De Pere today and soothe yourself in complete comfort tomorrow.

Frequently Asked Questions

How much does it cost to stay in a 5-star hotel in De Pere?

How much you pay for a 5-star hotel in De Pere depends on things such as when you want to go and the length of your stay. An insider tip for scoring an awesome deal? Use our pricing filters to check out all of the available accommodations for your selected dates.

What makes a hotel 5 stars in De Pere?

In De Pere, a hotel is required to offer a specific number of upscale conveniences to be rated 5 stars. These can include on-site gyms, spas and saunas, gourmet restaurants, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their exceptional standard of service. You can expect things like concierge services, in-room massages and nightly turn-down services. Some may also offer extra touches such as welcome gifts.

Are there any 5-star all-inclusive resorts in De Pere?

Find an indulgent escape that includes your lodging, food, activities and entertainment in De Pere with our handy filters. Search for hotels with a 5-star rating and click on the "All inclusive" filter. Double-check what's included in the upfront price. That way, you're ready to take advantage of the premium perks on offer from the moment you step into the lobby.

Are there any 5-star vacation rentals in De Pere?

There are no 5-star vacation rentals in De Pere on our site, but there are a few other top-rated properties worth checking out. Browse our vacation rentals in De Pere to book the ideal place for your getaway.

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