Title: The Best 5 Star Hotels in Mendrisio from $108 | Expedia.com [Mendrisio Travel Guide](https://expedia.com/Mendrisio.dx6023188)[Hotels in Mendrisio](https://expedia.com/Mendrisio-Hotels.d6023188.Travel-Guide-Hotels)[Vacation Rentals in Mendrisio](https://expedia.com/Mendrisio-Vacation-Rentals.d6023188.Travel-Guide-VacationRentals)[Flights to Mendrisio](https://expedia.com/Cheap-Flights-To-Mendrisio.d6023188.Travel-Guide-Flights)[Things to do in Mendrisio](https://expedia.com/Things-To-Do-In-Mendrisio.d6023188.Travel-Guide-Activities)[Car Rentals in Mendrisio](https://expedia.com/Car-Rentals-In-Mendrisio.d6023188.Car-Rental-Guide)[Mendrisio Vacation Packages](https://expedia.com/Mendrisio.d6023188.Destination-Travel-Guides) ![Panoramic aerial view of a Swiss city. Mendrisio with to the right the church of Saints Cosmas and Damian, Switzerland](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mendrisio 5 Star Hotels Tonight [Mar 9 - Mar 10](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-09&endDate=2026-03-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 10 - Mar 11](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-10&endDate=2026-03-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mendrisio 5-star hotels ![2 restaurants, lunch served](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/0d37c129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/9e1ed3e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/49293cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (W.Churchill Suite lake view) | View from room](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/29673087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Villa Serbelloni [](https://www.expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information) Historic Center 9.2/10 Wonderful (550 reviews) "Wonderful hotel and staff, loved our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Forrest $898 nightly $999 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information) ![Indoor pool, open 8:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/c2478cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/94abced3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/4a350bf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite Palace, Lake View | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/3ce996de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Splendide Royal [](https://www.expedia.com/Lugano-Hotels-Hotel-Splendide-Royal.h24059.Hotel-Information) Loreto 9.4/10 Exceptional (467 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) carla $125 nightly $142 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Lugano-Hotels-Hotel-Splendide-Royal.h24059.Hotel-Information) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/80b01cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/697457d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Lake View | Lake view](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/acc37209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/d899a484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Victoria Concept & Spa, by R Collection Hotels [](https://www.expedia.com/Menaggio-Hotels-Grand-Hotel-Victoria-Concept-Spa.h44262769.Hotel-Information) Menaggio 9.8/10 Exceptional (95 reviews) "Amazing hotel, nice spacious rooms, great breakfast and restaurant for evening." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Anonymous traveler $631 nightly $695 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Menaggio-Hotels-Grand-Hotel-Victoria-Concept-Spa.h44262769.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/daec4940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Lake View | Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/4e296b33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Lake View | Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/74e81f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Lake View (Balcony) | Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/b2d19b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lake Como EDITION [](https://www.expedia.com/Griante-Hotels-Hotel-Britannia-Excelsior.h1501807.Hotel-Information) Griante 8.0/10 Very Good (1 review) "Pool was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert $650 nightly $726 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Griante-Hotels-Hotel-Britannia-Excelsior.h1501807.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/dc8ce358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mandarin, Suite | Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/01473ca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/8a573326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/7cb22249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mandarin Oriental, Lago di Como [](https://www.expedia.com/Blevio-Hotels-Mandarin-Oriental.h3684389.Hotel-Information) Blevio 9.4/10 Exceptional (483 reviews) "Hotel, room and staffs were excellent. I absolutely recommend this hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JUDE [](https://www.expedia.com/Blevio-Hotels-Mandarin-Oriental.h3684389.Hotel-Information) ![Staircase](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/6a888a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/7900bf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/0d6d36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/ceabe4d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Venezia [](https://www.expedia.com/Como-Hotels-Vista-Palazzo-Small-Luxury-Hotel.h19134514.Hotel-Information) Como City Centre 9.8/10 Exceptional (122 reviews) "Stunning hotel with beautiful views of Lake Como. The room was spotless and looked as if we were the first guests in it because it was so clean. The highest end fixtures and finishings I’ve ever seen in any hotel. The breakfast was nothing less than 5 Star. I would strongly recommend this hotel to anyone looking for the best in Como. Thank you to the staff for making it perfect " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Avo $661 nightly $739 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Como-Hotels-Vista-Palazzo-Small-Luxury-Hotel.h19134514.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/5c9de641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with satellite channels](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/60fc0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/4e92b857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/ddccecbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Principe Leopoldo [](https://www.expedia.com/Lugano-Hotels-Villa-Principe-Leopoldo.h47139.Hotel-Information) Loreto 9.2/10 Wonderful (348 reviews) "The hospitality is very attentin" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isabella $371 nightly $398 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Lugano-Hotels-Villa-Principe-Leopoldo.h47139.Hotel-Information) ![Balcony view](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/a63a9b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/2684a608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/94388290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/89825982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Resort Collina d'Oro, Starhotels Collezione [](https://www.expedia.com/Collina-DOro-Hotels-Resort-Collina-DOro.h7330325.Hotel-Information) Collina d'Oro 9.2/10 Wonderful (169 reviews) "Excellent resort" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory $154 nightly $171 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Collina-DOro-Hotels-Resort-Collina-DOro.h7330325.Hotel-Information) ![Indoor pool, outdoor pool, sun loungers](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/04cd62b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake View One Bedroom Loggia Suite | Terrace/patio](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/ac64b803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/9c6afc84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/71bd60a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ARIA Retreat & SPA - The Leading Hotels of the World [](https://www.expedia.com/Porlezza-Hotels-Aria-Retreat-SPA.h51914041.Hotel-Information) Porlezza 9.8/10 Exceptional (79 reviews) "This was the nicest hotel that we have ever stayed at, and the food was out of this world." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy $642 nightly $713 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Porlezza-Hotels-Aria-Retreat-SPA.h51914041.Hotel-Information) ![Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/1e301534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/9edc3a0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/87852d13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/db7f2529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Villa Castagnola [](https://www.expedia.com/Lugano-Hotels-Grand-Hotel-Villa-Castagnola.h28471.Hotel-Information) Cassarate 9.6/10 Exceptional (395 reviews) "It was a beautiful hotel with a lot of history. Very traditional, look with many amenities and great restaurant. The views from the room of Lake Lugano were breathtaking. I would strongly suggest this hotel if you’re staying in Lugano." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Avo $595 nightly $630 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Lugano-Hotels-Grand-Hotel-Villa-Castagnola.h28471.Hotel-Information) ![Junior Suite, Lake View, Annex Building (in grotta) | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/0a57cb9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Lake View, Annex Building (private garden Darsena) | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/b70ecdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Lake View, Annex Building (in grotta) | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/a2187c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Lake View, Annex Building (in grotta) | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/1e108cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Lario Resort Mandello [](https://www.expedia.com/Mandello-Del-Lario-Hotels-Villa-Lario-Resort-Mandello.h14837841.Hotel-Information) Mandello del Lario 9.8/10 Exceptional (38 reviews) "Great well run resort" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) gordon $628 nightly $701 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Mandello-Del-Lario-Hotels-Villa-Lario-Resort-Mandello.h14837841.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/0c262dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/3dad6101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/4baea840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake view](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/6db55adb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Passalacqua [](https://www.expedia.com/Moltrasio-Hotels-Passalacqua.h24201147.Hotel-Information) Moltrasio 10/10 Exceptional (18 reviews) "Entire hotel is a 12/10 but add in that they have ALL the Dyson products in each room!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) bernard $1,743 nightly $1,929 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Moltrasio-Hotels-Passalacqua.h24201147.Hotel-Information) ![Suite | Down comforters, in-room safe, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/b6eb0c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite | Down comforters, in-room safe, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/18989b20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite | Down comforters, in-room safe, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/586a2912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/5daa0c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Campione [](https://www.expedia.com/Campione-DItalia-Hotels-Grand-Hotel-Campione.h36832673.Hotel-Information) Campione d'Italia 9.0/10 Wonderful (167 reviews) "Very good breakfast and welcoming atmosphere " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Ehab $339 nightly $373 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Campione-DItalia-Hotels-Grand-Hotel-Campione.h36832673.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/809690c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, Select Comfort beds](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/2adae67e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 King Bed with Sofa bed, Terrace, Lake View | 1 bedroom, premium bedding, down comforters, Select Comfort beds](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/78f8b834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 King Bed with Sofa bed, Terrace, Lake View | Living area | LCD TV, pay movies](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/3f1048e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The View Lugano [](https://www.expedia.com/Paradiso-Hotels-The-View-Lugano.h11780806.Hotel-Information) Paradiso 9.6/10 Exceptional (157 reviews) "Wonderful hotel, can’t praise it enough. Look forward to our next stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan $681 nightly $719 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Paradiso-Hotels-The-View-Lugano.h11780806.Hotel-Information) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/45ac639e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/5c4f485b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/a3776c28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/988a8310.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swiss Diamond Hotel & SPA [](https://www.expedia.com/Vico-Morcote-Hotels-Swiss-Diamond-Hotel.h972505.Hotel-Information) Vico Morcote 9.0/10 Wonderful (436 reviews) "Beautiful property, very friendly and helpful staff. The breakfast buffet was excellent! We had a wonderful time." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sabrina $440 nightly $469 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Vico-Morcote-Hotels-Swiss-Diamond-Hotel.h972505.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/6d77591e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/c0f3f8f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/ea960e9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/w4386h6553x0y26-2c7d4562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swiss Diamond Boutique Hotel La Romantica [](https://www.expedia.com/Melide-Hotels-Swiss-Diamond-Boutique-Hotel-La-Romantica.h112636609.Hotel-Information) Melide 9.8/10 Exceptional (18 reviews) "Beautiful location and friendly staffs are impressive. Would love to visit again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan $506 nightly $538 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Melide-Hotels-Swiss-Diamond-Boutique-Hotel-La-Romantica.h112636609.Hotel-Information) ![SOLE LUXURY ROOM WITH SPECTACULAR VIEW | Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/104000000/103950000/103941400/103941364/2189788c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103950000/103941400/103941364/594b0335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![SOLE LUXURY ROOM WITH SPECTACULAR VIEW | Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/104000000/103950000/103941400/103941364/1e2dcff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/104000000/103950000/103941400/103941364/c349bb72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nuvole Garden Hotel [](https://www.expedia.com/Brunate-Hotels-Nuvole-Garden-Hotel.h103941364.Hotel-Information) Brunate 8.4/10 Very Good (8 reviews) "Amazing room, amazing views and amazing staff... 100% going back!" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Richard $850 nightly $947 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Brunate-Hotels-Nuvole-Garden-Hotel.h103941364.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/8e70820d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Non Smoking, Mountain View | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/487154f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, City View | Living area | 55-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/d0c12bb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, City View | Terrace/patio](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/02582ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swiss Hotel Apartments - Lugano [](https://www.expedia.com/Lugano-Hotels-Swiss-Hotel-Apartments-Lugano.h76573521.Hotel-Information) Lugano City-Centre 8.6/10 Excellent (18 reviews) "Great property and location. Apartments were very clean and had all the amenities you would need. Communication with office staff was great and they were always available if needed. Would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana $235 nightly $250 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Lugano-Hotels-Swiss-Hotel-Apartments-Lugano.h76573521.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/51ee9c30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/c5956260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Lake View | Balcony view](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/e463ce03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/f61899c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Eden Roc [](https://www.expedia.com/Ascona-Hotels-Hotel-Eden-Roc.h522870.Hotel-Information) Ascona 9.4/10 Exceptional (129 reviews) "Super Hotel! " ![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg) Stephan $732 nightly $772 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Ascona-Hotels-Hotel-Eden-Roc.h522870.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/47000000/46170000/46161300/46161238/fc315eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Lake View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/47000000/46170000/46161300/46161238/ad9bfb07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/47000000/46170000/46161300/46161238/9bcc57cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Lake View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/47000000/46170000/46161300/46161238/ffbff3c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bianca Relais - by R Collection Hotels [](https://www.expedia.com/Oggiono-Hotels-Bianca-Relais.h46161238.Hotel-Information) Oggiono 9.8/10 Exceptional (50 reviews) "simple n modern design beautiful lakeview" ![Hong Kong SAR China](https://a.travel-assets.com/egds/marks/flags/hk.svg) Po Mei $260 nightly $287 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Oggiono-Hotels-Bianca-Relais.h46161238.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mendrisio-Hotels.s50-0-d6023188.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mendrisio-Hotels.s50-0-d6023188.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mendrisio. ![Hotel Osteria della Pista](https://images.trvl-media.com/lodging/3000000/2530000/2523100/2523034/06441981_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Osteria della Pista Via Verbano 1 Casorate Sempione VA $106 nightly $117 total Mar 12 - Mar 13 Total with taxes and fees 9.4/10 Exceptional! (1,254 reviews) [](https://expedia.com/Milan-Hotels-Hotel-Osteria-Della-Pista.h2523034.Hotel-Information) ![Idea Hotel Milano Malpensa Airport](https://images.trvl-media.com/lodging/4000000/3980000/3970100/3970024/1f8bad56_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Idea Hotel Milano Malpensa Airport Via Della Chiesa, 27 Somma Lombardo VA $94 nightly $108 total Mar 23 - Mar 24 Total with taxes and fees 7.4/10 Good! (1,003 reviews) [](https://expedia.com/Milan-Hotels-Idea-Hotel-Milano-Malpensa-Airport.h3970024.Hotel-Information) ![Crowne Plaza Milan - Malpensa Airport by IHG](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427867/6556f277_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Crowne Plaza Milan - Malpensa Airport by IHG Via Arturo Ferrarin, 7 Somma Lombardo VA $99 nightly $114 total Mar 16 - Mar 17 Total with taxes and fees 8.4/10 Very Good! (1,013 reviews) [](https://expedia.com/Milan-Hotels-Crowne-Plaza-Malpensa-Airport.h1427867.Hotel-Information) Still don't see what you're looking for? [See all properties in Mendrisio.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F10%2F2026&endDate=3%2F11%2F2026®ionId=6023188&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F10%2F2026&endDate=3%2F11%2F2026®ionId=6023188&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F10%2F2026&endDate=3%2F11%2F2026®ionId=6023188&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F10%2F2026&endDate=3%2F11%2F2026®ionId=6023188&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F10%2F2026&endDate=3%2F11%2F2026®ionId=6023188&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F10%2F2026&endDate=3%2F11%2F2026®ionId=6023188&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mendrisio Tucked between Lake Lugano and Generoso Mount, this charming town invites you to explore its cultural treasures at Museum d'Art and Galleria Baumgartner. Bargain hunters flock to FoxTown Factory Stores while nature lovers can discover the UNESCO-listed Monte San Giorgio with its remarkable fossil deposits. [See all hotels in Mendrisio](https://www.expedia.com/Hotel-Search?startDate=2026-03-23&endDate=2026-03-24&adults=2®ionId=6023188) ![Panoramic aerial view of a Swiss city. Mendrisio with to the right the church of Saints Cosmas and Damian, Switzerland](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=900&h=296&p=1&q=high) ## Top Mendrisio Hotel Reviews ![Grand Hotel Villa Serbelloni](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/0d37c129_y.jpg) ### Grand Hotel Villa Serbelloni 10/10 Excellent "The staff were wonderful and the hotel was impeccable. All amenities were extremely thoughtful." [](https://expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information) ## Find out more about Mendrisio Treat yourself on your next getaway. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Mendrisio so popular in the last year. There's no reason to delay a getaway to Mendrisio any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Mendrisio and get ready to be pampered like never before. Don't wait any longer! ### 5-Star Hotels in Mendrisio You'll have a wonderful time at one of these 5-star hotels. Michelin-starred restaurants, concierges, and in-room massages are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? A full-body massage to help your cares fall away? A concierge to help you pick out your next adventure? Beautiful furniture, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. Ready for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mendrisio are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. ### Make Your Escape The results are in, and Mendrisio 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of Expedia's Mendrisio 5-star hotels today and soothe yourself in total tranquility tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Mendrisio? ### How much does it cost to stay in a 5-star hotel in Mendrisio? > - Search for the lowest price per night from $108 ### What makes a hotel 5 stars in Mendrisio? ## Explore a world of travel with Expedia - More ways to book - [Book 5 Star Hotels in Mendrisio on Expedia.ch ](https://www.expedia.ch/5Sterne-Mendrisio-Hotel.s50-0-d6023188.Reise-Angebote-Filter-Hotels)