Title: The Best 5 Star Hotels in Mendrisio from $104 | Expedia.com

[Mendrisio Travel Guide](https://expedia.com/Mendrisio.dx6023188)[Hotels in Mendrisio](https://expedia.com/Mendrisio-Hotels.d6023188.Travel-Guide-Hotels)[Vacation Rentals in Mendrisio](https://expedia.com/Mendrisio-Vacation-Rentals.d6023188.Travel-Guide-VacationRentals)[Flights to Mendrisio](https://expedia.com/Cheap-Flights-To-Mendrisio.d6023188.Travel-Guide-Flights)[Things to do in Mendrisio](https://expedia.com/Things-To-Do-In-Mendrisio.d6023188.Travel-Guide-Activities)[Car Rentals in Mendrisio](https://expedia.com/Car-Rentals-In-Mendrisio.d6023188.Car-Rental-Guide)[Mendrisio Vacation Packages](https://expedia.com/Mendrisio.d6023188.Destination-Travel-Guides)

![Panoramic aerial view of a Swiss city. Mendrisio with to the right the church of Saints Cosmas and Damian, Switzerland](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Mendrisio 5 Star Hotels

Tonight

[Mar 16 - Mar 17](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-16&endDate=2026-03-17&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 17 - Mar 18](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-17&endDate=2026-03-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Mendrisio 5-star hotels

![Garden](https://images.trvl-media.com/lodging/59000000/58950000/58946700/58946683/7d6cde6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/59000000/58950000/58946700/58946683/ebfc1045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop Front Suite | View from room](https://images.trvl-media.com/lodging/59000000/58950000/58946700/58946683/6be367a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/59000000/58950000/58946700/58946683/7b2c758d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Tremezzo

[](https://www.expedia.com/Tremezzina-Hotels-Grand-Hotel-Tremezzo.h58946683.Hotel-Information)

Tremezzina

9.8/10

Exceptional

(87 reviews)

"Nicest hotel I’ve ever stayed in - unbelievable experience all around."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jordan

$935 nightly

$1,040 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Tremezzina-Hotels-Grand-Hotel-Tremezzo.h58946683.Hotel-Information)

![2 restaurants, lunch served](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/0d37c129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/a60e84ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/49293cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (W.Churchill Suite lake view) | View from room](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/29673087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Villa Serbelloni

[](https://www.expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information)

Historic Center

9.2/10

Wonderful

(550 reviews)

"Wonderful hotel and staff, loved our stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Forrest

$882 nightly

$982 total

Mar 20 - Mar 21

Total with taxes and fees

[](https://www.expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information)

![Indoor pool, open 8:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/c2478cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/94abced3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/4a350bf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite Palace, Lake View | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/eaa8189f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Splendide Royal

[](https://www.expedia.com/Lugano-Hotels-Hotel-Splendide-Royal.h24059.Hotel-Information)

Loreto

9.4/10

Exceptional

(468 reviews)

"Great facility"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

olga

$144 nightly

$161 total

Mar 18 - Mar 19

Total with taxes and fees

[](https://www.expedia.com/Lugano-Hotels-Hotel-Splendide-Royal.h24059.Hotel-Information)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/daec4940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/2f08201c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Lake View | Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/4e296b33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Lake View (Balcony) | Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/b2d19b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Lake Como EDITION

[](https://www.expedia.com/Griante-Hotels-Hotel-Britannia-Excelsior.h1501807.Hotel-Information)

Griante

8.0/10

Very Good

(1 review)

"Pool was excellent"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

$698 nightly

$779 total

Mar 17 - Mar 18

Total with taxes and fees

[](https://www.expedia.com/Griante-Hotels-Hotel-Britannia-Excelsior.h1501807.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/dc8ce358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/c35d3b34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/7cb22249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/8a573326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mandarin Oriental, Lago di Como

[](https://www.expedia.com/Blevio-Hotels-Mandarin-Oriental.h3684389.Hotel-Information)

Blevio

9.4/10

Exceptional

(483 reviews)

"Hotel, room and staffs were excellent. I absolutely recommend this hotel."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JUDE

[](https://www.expedia.com/Blevio-Hotels-Mandarin-Oriental.h3684389.Hotel-Information)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/80b01cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Lake View | Lake view](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/acc37209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite, Lake View | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/0cfefc67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/697457d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Victoria Concept & Spa, by R Collection Hotels

[](https://www.expedia.com/Menaggio-Hotels-Grand-Hotel-Victoria-Concept-Spa.h44262769.Hotel-Information)

Menaggio

9.8/10

Exceptional

(95 reviews)

"Amazing hotel, nice spacious rooms, great breakfast and restaurant for evening."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Anonymous traveler

$562 nightly

$619 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Menaggio-Hotels-Grand-Hotel-Victoria-Concept-Spa.h44262769.Hotel-Information)

![Balcony view](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/a63a9b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/2684a608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/94388290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/bee644b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Resort Collina d'Oro, Starhotels Collezione

[](https://www.expedia.com/Collina-DOro-Hotels-Resort-Collina-DOro.h7330325.Hotel-Information)

Collina d'Oro

9.2/10

Wonderful

(170 reviews)

"Clean and super nice! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

elizabetta

$176 nightly

$195 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Collina-DOro-Hotels-Resort-Collina-DOro.h7330325.Hotel-Information)

![Staircase](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/6a888a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/0d6d36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/7900bf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/4abd91c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Venezia

[](https://www.expedia.com/Como-Hotels-Vista-Palazzo-Small-Luxury-Hotel.h19134514.Hotel-Information)

Como City Centre

9.8/10

Exceptional

(123 reviews)

"Stunning hotel with beautiful views of Lake Como. The room was spotless and looked as if we were the first guests in it because it was so clean. The highest end fixtures and finishings I’ve ever seen in any hotel. The breakfast was nothing less than 5 Star. I would strongly recommend this hotel to anyone looking for the best in Como. Thank you to the staff for making it perfect "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Avo

$585 nightly

$655 total

Mar 31 - Apr 1

Total with taxes and fees

[](https://www.expedia.com/Como-Hotels-Vista-Palazzo-Small-Luxury-Hotel.h19134514.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/5c9de641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/ddccecbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/4e92b857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with satellite channels](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/60fc0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Principe Leopoldo

[](https://www.expedia.com/Lugano-Hotels-Villa-Principe-Leopoldo.h47139.Hotel-Information)

Loreto

9.2/10

Wonderful

(349 reviews)

"The hospitality is very attentin"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Isabella

$338 nightly

$363 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Lugano-Hotels-Villa-Principe-Leopoldo.h47139.Hotel-Information)

![Indoor pool, outdoor pool, sun loungers](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/04cd62b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/71bd60a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/9c6afc84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![LAGO Penthouse Suite | Terrace/patio](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/9b54400e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ARIA Retreat & SPA - The Leading Hotels of the World

[](https://www.expedia.com/Porlezza-Hotels-Aria-Retreat-SPA.h51914041.Hotel-Information)

Porlezza

9.8/10

Exceptional

(79 reviews)

"This was the nicest hotel that we have ever stayed at, and the food was out of this world."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeremy

$631 nightly

$700 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Porlezza-Hotels-Aria-Retreat-SPA.h51914041.Hotel-Information)

![Junior Suite, Lake View, Annex Building (in grotta) | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/0a57cb9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Vista Lago Parziale | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/10f54dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, Lake View (private terrace) | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/1cc36931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Lake View, Annex Building (private garden Darsena) | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/b70ecdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Lario Resort Mandello

[](https://www.expedia.com/Mandello-Del-Lario-Hotels-Villa-Lario-Resort-Mandello.h14837841.Hotel-Information)

Mandello del Lario

9.8/10

Exceptional

(38 reviews)

"Great well run resort"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

gordon

$618 nightly

$688 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Mandello-Del-Lario-Hotels-Villa-Lario-Resort-Mandello.h14837841.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/0c262dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/3dad6101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lake view](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/6db55adb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/4baea840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Passalacqua

[](https://www.expedia.com/Moltrasio-Hotels-Passalacqua.h24201147.Hotel-Information)

Moltrasio

10/10

Exceptional

(18 reviews)

"Entire hotel is a 12/10 but add in that they have ALL the Dyson products in each room!!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

bernard

$1,484 nightly

$1,644 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Moltrasio-Hotels-Passalacqua.h24201147.Hotel-Information)

![Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/1e301534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sauna, steam room, Turkish bath, body treatments, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/6ae6f0b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/87852d13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/9edc3a0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Villa Castagnola

[](https://www.expedia.com/Lugano-Hotels-Grand-Hotel-Villa-Castagnola.h28471.Hotel-Information)

Cassarate

9.6/10

Exceptional

(395 reviews)

"It was a beautiful hotel with a lot of history. Very traditional, look with many amenities and great restaurant. The views from the room of Lake Lugano were breathtaking. I would strongly suggest this hotel if you’re staying in Lugano."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Avo

$552 nightly

$585 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Lugano-Hotels-Grand-Hotel-Villa-Castagnola.h28471.Hotel-Information)

![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/809690c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite, 1 King Bed with Sofa bed, Terrace, Lake View | 1 bedroom, premium bedding, down comforters, Select Comfort beds](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/78f8b834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, down comforters, Select Comfort beds](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/2adae67e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Porch](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/75a98b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The View Lugano

[](https://www.expedia.com/Paradiso-Hotels-The-View-Lugano.h11780806.Hotel-Information)

Paradiso

9.6/10

Exceptional

(157 reviews)

"Wonderful hotel, can’t praise it enough. Look forward to our next stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jonathan

$654 nightly

$691 total

Mar 17 - Mar 18

Total with taxes and fees

[](https://www.expedia.com/Paradiso-Hotels-The-View-Lugano.h11780806.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/8e70820d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, City View | Living area | 55-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/d0c12bb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Non Smoking, Mountain View | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/487154f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, City View | Terrace/patio](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/02582ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Swiss Hotel Apartments - Lugano

[](https://www.expedia.com/Lugano-Hotels-Swiss-Hotel-Apartments-Lugano.h76573521.Hotel-Information)

Lugano City-Centre

8.6/10

Excellent

(18 reviews)

"Nice big apartment in a good location close to the center "

![Hong Kong SAR China](https://a.travel-assets.com/egds/marks/flags/hk.svg)

Kenneth

$223 nightly

$237 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Lugano-Hotels-Swiss-Hotel-Apartments-Lugano.h76573521.Hotel-Information)

![Suite | Down comforters, in-room safe, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/b6eb0c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Grand Suite | Down comforters, in-room safe, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/18989b20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sauna, steam room, massages](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/5a9dce7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Grand Suite | Down comforters, in-room safe, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/586a2912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Campione

[](https://www.expedia.com/Campione-DItalia-Hotels-Grand-Hotel-Campione.h36832673.Hotel-Information)

Campione d'Italia

9.0/10

Wonderful

(167 reviews)

"Very good breakfast and welcoming atmosphere "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Ehab

$350 nightly

$385 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/Campione-DItalia-Hotels-Grand-Hotel-Campione.h36832673.Hotel-Information)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/45ac639e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double or Twin Room, Balcony, Lake View | Lake view](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/8e586bde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/988a8310.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/a3776c28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Swiss Diamond Hotel & SPA

[](https://www.expedia.com/Vico-Morcote-Hotels-Swiss-Diamond-Hotel.h972505.Hotel-Information)

Vico Morcote

9.0/10

Wonderful

(436 reviews)

"Beautiful property, very friendly and helpful staff. The breakfast buffet was excellent! We had a wonderful time."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Sabrina

$348 nightly

$373 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Vico-Morcote-Hotels-Swiss-Diamond-Hotel.h972505.Hotel-Information)

![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/51ee9c30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/3e73da6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Lake View | Balcony view](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/e463ce03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/f61899c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Eden Roc

[](https://www.expedia.com/Ascona-Hotels-Hotel-Eden-Roc.h522870.Hotel-Information)

Ascona

9.4/10

Exceptional

(129 reviews)

"Super Hotel! "

![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg)

Stephan

$718 nightly

$758 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Ascona-Hotels-Hotel-Eden-Roc.h522870.Hotel-Information)

![Couples treatment rooms, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/3000000/2920000/2919900/2919854/2dd3463b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room (DELUXE DOUBLE ROOM WITH PRIVATE POOL) | Hypo-allergenic bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/3000000/2920000/2919900/2919854/543cfb87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, Mountain View | Mountain view](https://images.trvl-media.com/lodging/3000000/2920000/2919900/2919854/af0ec1a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2920000/2919900/2919854/7c08a136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### C-hotel & Spa

[](https://www.expedia.com/Cassago-Brianza-Hotels-C-Hotel-Spa.h2919854.Hotel-Information)

Cassago Brianza

9.0/10

Wonderful

(141 reviews)

"Great small family owned hotel. Greta for summer vacations. Nice staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yuri

$225 nightly

$248 total

Apr 11 - Apr 12

Total with taxes and fees

[](https://www.expedia.com/Cassago-Brianza-Hotels-C-Hotel-Spa.h2919854.Hotel-Information)

![Body treatments, deep-tissue massages, facials, manicures and pedicures](https://images.trvl-media.com/lodging/124000000/123200000/123192500/123192426/f7af27c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/124000000/123200000/123192500/123192426/6f684f60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/124000000/123200000/123192500/123192426/e2b82f44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/124000000/123200000/123192500/123192426/d141e91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo San Gottardo Lake Como, a Radisson Collection

[](https://www.expedia.com/Como-Hotels-Palazzo-San-Gottardo-Lake-Como.h123192426.Hotel-Information)

Como City Centre

$406 nightly

$458 total

Mar 19 - Mar 20

Total with taxes and fees

[](https://www.expedia.com/Como-Hotels-Palazzo-San-Gottardo-Lake-Como.h123192426.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mendrisio.

![Hotel Osteria della Pista](https://images.trvl-media.com/lodging/3000000/2530000/2523100/2523034/06441981_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Osteria della Pista

Via Verbano 1 Casorate Sempione VA

$100 nightly

$111 total

Mar 22 - Mar 23

Total with taxes and fees

9.4/10 Exceptional! (1,249 reviews)

[](https://expedia.com/Milan-Hotels-Hotel-Osteria-Della-Pista.h2523034.Hotel-Information)

![Crowne Plaza Milan - Malpensa Airport by IHG](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427867/6556f277_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Crowne Plaza Milan - Malpensa Airport by IHG

Via Arturo Ferrarin, 7 Somma Lombardo VA

$90 nightly

$104 total

Mar 22 - Mar 23

Total with taxes and fees

8.4/10 Very Good! (1,008 reviews)

[](https://expedia.com/Milan-Hotels-Crowne-Plaza-Malpensa-Airport.h1427867.Hotel-Information)

![Hotel Barchetta Excelsior](https://images.trvl-media.com/lodging/1000000/20000/14200/14103/9a3ce571_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Barchetta Excelsior

Piazza Cavour 1 Como CO

$159 nightly

$186 total

Mar 26 - Mar 27

Total with taxes and fees

8.8/10 Excellent! (1,001 reviews)

[](https://expedia.com/Como-Hotels-Hotel-Barchetta-Excelsior.h14103.Hotel-Information)

Still don't see what you're looking for?

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[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&regionId=6023188&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&regionId=6023188&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&regionId=6023188&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&regionId=6023188&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&regionId=6023188&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Mendrisio

Tucked between Lake Lugano and Generoso Mount, this charming town invites you to explore its cultural treasures at Museum d'Art and Galleria Baumgartner. Bargain hunters flock to FoxTown Factory Stores while nature lovers can discover the UNESCO-listed Monte San Giorgio with its remarkable fossil deposits.

[See all hotels in Mendrisio](https://www.expedia.com/Hotel-Search?startDate=2026-03-30&endDate=2026-03-31&adults=2&regionId=6023188)

![Panoramic aerial view of a Swiss city. Mendrisio with to the right the church of Saints Cosmas and Damian, Switzerland](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=900&h=296&p=1&q=high)

## Top Mendrisio Hotel Reviews

![Grand Hotel Villa Serbelloni](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/0d37c129_y.jpg)

### Grand Hotel Villa Serbelloni

10/10 Excellent

"The staff were wonderful and the hotel was impeccable. All amenities were extremely thoughtful."

[](https://expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information)

## Find out more about Mendrisio

Treat yourself on your next getaway. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Mendrisio so popular in the last year. There's no reason to delay a getaway to Mendrisio any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Mendrisio and get ready to be pampered like never before. Don't wait any longer!

### 5-Star Hotels in Mendrisio

You'll have a wonderful time at one of these 5-star hotels. Michelin-starred restaurants, concierges, and in-room massages are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? A full-body massage to help your cares fall away? A concierge to help you pick out your next adventure? Beautiful furniture, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. 

Ready for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mendrisio are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. 

### Make Your Escape

The results are in, and Mendrisio 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of Expedia's Mendrisio 5-star hotels today and soothe yourself in total tranquility tomorrow.

## Frequently asked questions

### What are the best 5-star hotels in Mendrisio?

### How much does it cost to stay in a 5-star hotel in Mendrisio?

> - Search for the lowest price per night from $104

### What makes a hotel 5 stars in Mendrisio?

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