A town with a prominent church and mountains in the background.

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Check availability on Mendrisio 5 Star Hotels

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Mendrisio 5-star hotels

A resort with a pool, sun loungers, and a mountain backdrop.

1. Grand Hotel Tremezzo

Grand Hotel Tremezzo
5.0 star property
Tremezzina
9.8 out of 10, Exceptional, (105 reviews)
"Wonderful service but the food in the restaurant isn’t the best."
Canada
xiao lin
$948 nightly
The price is $1,054
Nov 1 - Nov 2
Total with taxes and fees
Grand Hotel Tremezzo
A room with a sofa, a coffee table, a decorative sculpture, a painting, and a window with a view of greenery.

2. Grand Hotel Villa Serbelloni

Grand Hotel Villa Serbelloni
5.0 star property
Historic Center
9.4 out of 10, Exceptional, (606 reviews)
"The breakfast buffet was excellent and a major attraction. The staff were very responsive. The front desk and concierge were very helpful in planning local trips. All in all they made our stay pleasant and memorable."
United States
Udayan
$866 nightly
The price is $963
Oct 27 - Oct 28
Total with taxes and fees
Grand Hotel Villa Serbelloni
A modern indoor pool area with a glass barrier, lounge chairs, and a stone column.

3. Palazzo San Gottardo Lake Como, a Radisson Collection

Palazzo San Gottardo Lake Como, a Radisson Collection
5.0 star property
Como City Centre
9.8 out of 10, Exceptional, (35 reviews)
"A new hotel in the great location near major attractions and nice restaurants. Good breakfast serves in the hotel restaurant, lots of choices. Great spa facility."
United States
Veronica
$326 nightly
The price is $370
Nov 8 - Nov 9
Total with taxes and fees
Palazzo San Gottardo Lake Como, a Radisson Collection
A lakeside property with a dock, boats, and a large building with a terrace overlooking the water.

4. Mandarin Oriental, Lago di Como

Mandarin Oriental, Lago di Como
5.0 star property
Cazzanore
9.4 out of 10, Exceptional, (508 reviews)
"Amazing trip"
United States
Christopher
$1,087 nightly
The price is $1,206
Oct 27 - Oct 28
Total with taxes and fees
Mandarin Oriental, Lago di Como
A modern building with a water feature in front.

5. Swiss Diamond Boutique Hotel La Romantica

Swiss Diamond Boutique Hotel La Romantica
5.0 star property
Melide
9.6 out of 10, Exceptional, (64 reviews)
"Excellent place"
United States
Anas
$318 nightly
The price is $341
Nov 25 - Nov 26
Total with taxes and fees
Swiss Diamond Boutique Hotel La Romantica
A pool area with lounge chairs and umbrellas, surrounded by mountains and a body of water.

6. The Lake Como EDITION

The Lake Como EDITION
5.0 star property
Griante
7.2 out of 10, Good, (22 reviews)
"The property was well maintained and the staff were very friendly and courteous. We enjoyed our stay."
United States
Ronald
$815 nightly
The price is $907
Oct 27 - Oct 28
Total with taxes and fees
The Lake Como EDITION
A pool area with lounge chairs and a view of a lake and mountains.

7. Grand Hotel Victoria Concept & Spa, by R Collection Hotels

Grand Hotel Victoria Concept & Spa, by R Collection Hotels
5.0 star property
Menaggio
9.8 out of 10, Exceptional, (159 reviews)
"We loved everything about this hotel! Absolutely beautiful hotel and rooms. The spa, wow! The staff and service go above and beyond! We can’t wait to go back!"
United States
Mandy
Grand Hotel Victoria Concept & Spa, by R Collection Hotels
A room with a view of a body of water and hills, featuring a blue sofa and a table with books.

8. Palazzo Venezia

Palazzo Venezia
5.0 star property
Como City Centre
9.8 out of 10, Exceptional, (129 reviews)
"Heavy construction around hotel was unfortunate but not the hotels fault. Staff was great and breakfast offering was superb. Great overall."
Canada
Hanif
$674 nightly
The price is $752
Nov 15 - Nov 16
Total with taxes and fees
Palazzo Venezia
A terrace with two lounge chairs and a green umbrella, overlooking a lake with buildings in the background.

9. Passalacqua

Passalacqua
5.0 star property
Moltrasio
10.0 out of 10, Exceptional, (21 reviews)
"Good hotel and personal "
United Kingdom
Pavel
$1,195 nightly
The price is $1,326
Nov 24 - Nov 25
Total with taxes and fees
Passalacqua
A swimming pool with a dining area and a view of mountains.

10. Swiss Diamond Hotel & SPA

Swiss Diamond Hotel & SPA
5.0 star property
Vico Morcote
9.0 out of 10, Wonderful, (468 reviews)
"Really enjoyed our stay, the staff were lovely and nothing was too much trouble for them. The rooms were amazing with a wonderful view and a very comfortable bed. Getting the bus was no problem stopped right outside the hotel, there was also a courtesy bus into Luganda where you can get a boat around the lake stopping at villages on route. I would not hesitate to recommend this hotel."
United Kingdom
susan
$317 nightly
The price is $340
Nov 25 - Nov 26
Total with taxes and fees
Swiss Diamond Hotel & SPA
A modern indoor pool area with a view of a lake and mountains.

11. Hotel Splendide Royal

Hotel Splendide Royal
5.0 star property
Loreto
9.4 out of 10, Exceptional, (514 reviews)
"Wonderful!"
United States
Christian
$303 nightly
The price is $326
Nov 3 - Nov 4
Total with taxes and fees
Hotel Splendide Royal
A view through a glass door to an outdoor seating area with wicker chairs and a wooden deck.

12. Boutique Hotel Stresa

Boutique Hotel Stresa
5.0 star property
Stresa
10.0 out of 10, Exceptional, (32 reviews)
"Absolutely beautiful hotel in a great location."
Canada
Ennio
$500 nightly
The price is $557
Oct 27 - Oct 28
Total with taxes and fees
Boutique Hotel Stresa
A covered walkway with arches, a view of a lake, and people walking.

13. ARIA Retreat & SPA - The Leading Hotels of the World

ARIA Retreat & SPA - The Leading Hotels of the World
5.0 star property
Porlezza
10.0 out of 10, Exceptional, (96 reviews)
"Perfect staff , clean property , well cared."
United States
Semih
ARIA Retreat & SPA - The Leading Hotels of the World
A large, two-story building with a symmetrical facade, a central entrance, and a well-maintained garden with a fountain.

14. Villa Principe Leopoldo

Villa Principe Leopoldo
5.0 star property
Loreto
9.2 out of 10, Wonderful, (383 reviews)
"Great stay"
United States
Sandeep
$414 nightly
The price is $441
Nov 2 - Nov 3
Total with taxes and fees
Villa Principe Leopoldo
A serene outdoor seating area with wicker furniture, cushions, and a table with a bowl and glasses, overlooking a calm lake with mountains in the background.

15. Grand Hotel Villa Castagnola

Grand Hotel Villa Castagnola
5.0 star property
Cassarate
9.6 out of 10, Exceptional, (428 reviews)
"The staff went all out to make our stay feel the most confortable and welcoming I have ever felt in a hotel. Friendly, knowledgeable, they definitely went the extra mile. The spa, the location, the grounds, all were just stunningly beautiful. Walkable to the center of the shops, restaurants and coffee places. I would live there if I could. It is just an amazing hotel."
United States
Gregory
$521 nightly
The price is $552
Nov 24 - Nov 25
Total with taxes and fees
Grand Hotel Villa Castagnola
A modern building with a pool, surrounded by a well-maintained lawn and mountains in the background.

16. Bianca Relais - by R Collection Hotels

Bianca Relais - by R Collection Hotels
5.0 star property
Oggiono
9.6 out of 10, Exceptional, (66 reviews)
"Fantastic stay and excellent breakfast. Quiet and zen atmosphere with a top italian class. Helpful and friendly staff that go all way out to make your stay a perfect one ! Well done, Bianca !"
United Kingdom
Poh Boon
$276 nightly
The price is $304
Nov 6 - Nov 7
Total with taxes and fees
Bianca Relais - by R Collection Hotels
A pool area with red and white striped canopies, a clear view of a cityscape in the background, and a palm tree in the foreground.

17. Nuvole Garden Hotel

Nuvole Garden Hotel
5.0 star property
Brunate
8.8 out of 10, Excellent, (24 reviews)
"The hotel is beautiful, and the staff was absolutely fantastic. They were very helpful and attentive, we had a wonderful stay, and would recommend it to everyone."
United States
Eric
$660 nightly
The price is $737
Oct 29 - Oct 30
Total with taxes and fees
Nuvole Garden Hotel
An aerial view of a resort with a central swimming pool surrounded by lounge chairs and umbrellas, set against a backdrop of mountains and a lake.

18. Collina d'Oro Resort & SPA

Collina d'Oro Resort & SPA
5.0 star property
Collina d'Oro
9.2 out of 10, Wonderful, (187 reviews)
"All was really very good"
United States
Inna
$207 nightly
The price is $226
Nov 1 - Nov 2
Total with taxes and fees
Collina d'Oro Resort & SPA
A balcony with two chairs and a small table, overlooking a body of water and mountains.

19. Grand Hotel Campione

Grand Hotel Campione
5.0 star property
Campione d'Italia
9.0 out of 10, Wonderful, (177 reviews)
"Very nice hotel with a beutiful view"
Sweden
Johan
$374 nightly
The price is $412
Oct 27 - Oct 28
Total with taxes and fees
Grand Hotel Campione
A hotel with a courtyard, a pond, and a reflection of the building.

20. Giardino Ascona

Giardino Ascona
5.0 star property
Ascona
9.8 out of 10, Exceptional, (84 reviews)
"The people, the facility, the ambience, the scenery were all outstanding. Highly recommend this hotel to anyone seeking rest and relaxation."
United States
Etzel
Giardino Ascona
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mendrisio.
Idea Hotel Milano Malpensa Airport

Idea Hotel Milano Malpensa Airport

Via Della Chiesa, 27 Somma Lombardo VA
$89 nightly
The price is $102 total per night from Nov 16 to Nov 17
$102 total
Nov 16 - Nov 17
Total with taxes and fees
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Learn more about Mendrisio

Tucked between Lake Lugano and Generoso Mount, this charming town invites you to explore its cultural treasures at Museum d'Art and Galleria Baumgartner. Bargain hunters flock to FoxTown Factory Stores while nature lovers can discover the UNESCO-listed Monte San Giorgio with its remarkable fossil deposits.

See all hotels in Mendrisio
A town with a prominent church and mountains in the background.

Top Mendrisio Hotel Reviews

Grand Hotel Villa Serbelloni

Grand Hotel Villa Serbelloni

10/10 Excellent
"Excellent exp"
Michele 3-night trip
Posted 1 day ago
Grand Hotel Villa Serbelloni

Find out more about Mendrisio

Treat yourself on your next getaway. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Mendrisio so popular in the last year. There's no reason to delay a getaway to Mendrisio any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Mendrisio and get ready to be pampered like never before. Don't wait any longer!

5-Star Hotels in Mendrisio

You'll have a wonderful time at one of these 5-star hotels. Michelin-starred restaurants, concierges, and in-room massages are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? A full-body massage to help your cares fall away? A concierge to help you pick out your next adventure? Beautiful furniture, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed.

Ready for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mendrisio are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Make Your Escape

The results are in, and Mendrisio 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of Expedia's Mendrisio 5-star hotels today and soothe yourself in total tranquility tomorrow.

Frequently asked questions

What are the best 5-star hotels in Mendrisio?
According to Expedia guest reviews, Swiss Diamond Hotel & SPA, Resort Collina dOro and The View Lugano are some of the top 5-star hotels in Mendrisio. Featuring top-of-the-line amenities and excellent service, you'll enjoy a luxurious and comfortable stay.
How much does it cost to stay in a 5-star hotel in Mendrisio?
How much you pay for a 5-star hotel in Mendrisio depends on factors such as when you plan to go and the length of your getaway. A top tip for landing an awesome deal? Use our pricing filters to compare all of the available accommodations for your selected dates.

  • Search for the lowest price per night from $99

What makes a hotel 5 stars in Mendrisio?
Faultless guest service is the defining feature of every 5-star hotel in Mendrisio. From the second you arrive, staff ensure your every need is met, whether recommending activities and tours or providing a turn-down service. On top of that, hotels have to offer upscale conveniences to be considered for a 5-star rating. These can include luxury baths, an on-site spa, swimming pools, fine dining kitchens and knowledgeable concierge.

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