Title: The Best 5 Star Hotels in Mendrisio from $108 | Expedia.com

[Mendrisio Travel Guide](https://expedia.com/Mendrisio.dx6023188)[Hotels in Mendrisio](https://expedia.com/Mendrisio-Hotels.d6023188.Travel-Guide-Hotels)[Vacation Rentals in Mendrisio](https://expedia.com/Mendrisio-Vacation-Rentals.d6023188.Travel-Guide-VacationRentals)[Flights to Mendrisio](https://expedia.com/Cheap-Flights-To-Mendrisio.d6023188.Travel-Guide-Flights)[Things to do in Mendrisio](https://expedia.com/Things-To-Do-In-Mendrisio.d6023188.Travel-Guide-Activities)[Car Rentals in Mendrisio](https://expedia.com/Car-Rentals-In-Mendrisio.d6023188.Car-Rental-Guide)[Mendrisio Vacation Packages](https://expedia.com/Mendrisio.d6023188.Destination-Travel-Guides)

![Panoramic aerial view of a Swiss city. Mendrisio with to the right the church of Saints Cosmas and Damian, Switzerland](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Mendrisio 5 Star Hotels

Tonight

[Mar 5 - Mar 6](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-05&endDate=2026-03-06&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 6 - Mar 7](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-06&endDate=2026-03-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6023188&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Mendrisio 5-star hotels

![2 restaurants, lunch served](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/0d37c129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/9e1ed3e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/49293cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (W.Churchill Suite lake view) | View from room](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/29673087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Villa Serbelloni

[](https://www.expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information)

Historic Center

9.2/10

Wonderful

(550 reviews)

"Wonderful hotel and staff, loved our stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Forrest

$897 nightly

$998 total

Mar 23 - Mar 24

Total with taxes and fees

[](https://www.expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information)

![Indoor pool, open 8:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/c2478cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite Palace, Lake View | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/eaa8189f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/94abced3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite Palace, Lake View | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24100/24059/3ce996de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Splendide Royal

[](https://www.expedia.com/Lugano-Hotels-Hotel-Splendide-Royal.h24059.Hotel-Information)

Loreto

9.4/10

Exceptional

(466 reviews)

"Great place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

carla

$199 nightly

$219 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Lugano-Hotels-Hotel-Splendide-Royal.h24059.Hotel-Information)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/80b01cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite, Lake View | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/0cfefc67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/d899a484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Lake View | Lake view](https://images.trvl-media.com/lodging/45000000/44270000/44262800/44262769/acc37209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Victoria Concept & Spa, by R Collection Hotels

[](https://www.expedia.com/Menaggio-Hotels-Grand-Hotel-Victoria-Concept-Spa.h44262769.Hotel-Information)

Menaggio

9.8/10

Exceptional

(95 reviews)

"Beautiful property with excellent service."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gabriel

$591 nightly

$651 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Menaggio-Hotels-Grand-Hotel-Victoria-Concept-Spa.h44262769.Hotel-Information)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/daec4940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/2f08201c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Lake View (Balcony) | Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/b2d19b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Lake View | Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/2000000/1510000/1501900/1501807/4e296b33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Lake Como EDITION

[](https://www.expedia.com/Griante-Hotels-Hotel-Britannia-Excelsior.h1501807.Hotel-Information)

Griante

8.0/10

Very Good

(1 review)

"Pool was excellent"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

$650 nightly

$727 total

Mar 24 - Mar 25

Total with taxes and fees

[](https://www.expedia.com/Griante-Hotels-Hotel-Britannia-Excelsior.h1501807.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/dc8ce358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/7cb22249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Mandarin, Suite | Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/01473ca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/4000000/3690000/3684400/3684389/8a573326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mandarin Oriental, Lago di Como

[](https://www.expedia.com/Blevio-Hotels-Mandarin-Oriental.h3684389.Hotel-Information)

Blevio

9.4/10

Exceptional

(483 reviews)

"Hotel, room and staffs were excellent. I absolutely recommend this hotel."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JUDE

[](https://www.expedia.com/Blevio-Hotels-Mandarin-Oriental.h3684389.Hotel-Information)

![Staircase](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/6a888a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/7900bf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/0d6d36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/20000000/19140000/19134600/19134514/ceabe4d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Venezia

[](https://www.expedia.com/Como-Hotels-Vista-Palazzo-Small-Luxury-Hotel.h19134514.Hotel-Information)

Como City Centre

9.8/10

Exceptional

(122 reviews)

"Stunning hotel with beautiful views of Lake Como. The room was spotless and looked as if we were the first guests in it because it was so clean. The highest end fixtures and finishings I’ve ever seen in any hotel. The breakfast was nothing less than 5 Star. I would strongly recommend this hotel to anyone looking for the best in Como. Thank you to the staff for making it perfect "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Avo

$676 nightly

$756 total

Mar 17 - Mar 18

Total with taxes and fees

[](https://www.expedia.com/Como-Hotels-Vista-Palazzo-Small-Luxury-Hotel.h19134514.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/5c9de641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with satellite channels](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/60fc0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/ddccecbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/4e92b857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Principe Leopoldo

[](https://www.expedia.com/Lugano-Hotels-Villa-Principe-Leopoldo.h47139.Hotel-Information)

Loreto

9.2/10

Wonderful

(347 reviews)

"The hospitality is very attentin"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Isabella

$349 nightly

$375 total

Mar 10 - Mar 11

Total with taxes and fees

[](https://www.expedia.com/Lugano-Hotels-Villa-Principe-Leopoldo.h47139.Hotel-Information)

![Balcony view](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/a63a9b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/bee644b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/89825982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/94388290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Resort Collina d'Oro, Starhotels Collezione

[](https://www.expedia.com/Collina-DOro-Hotels-Resort-Collina-DOro.h7330325.Hotel-Information)

Collina d'Oro

9.2/10

Wonderful

(168 reviews)

"Excellent resort"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gregory

$160 nightly

$178 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Collina-DOro-Hotels-Resort-Collina-DOro.h7330325.Hotel-Information)

![Indoor pool, outdoor pool, sun loungers](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/04cd62b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/9c6afc84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lake View One Bedroom Loggia Suite | Terrace/patio](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/ac64b803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/52000000/51920000/51914100/51914041/71bd60a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ARIA Retreat & SPA - The Leading Hotels of the World

[](https://www.expedia.com/Porlezza-Hotels-Aria-Retreat-SPA.h51914041.Hotel-Information)

Porlezza

9.8/10

Exceptional

(79 reviews)

"This was the nicest hotel that we have ever stayed at, and the food was out of this world."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeremy

$643 nightly

$714 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Porlezza-Hotels-Aria-Retreat-SPA.h51914041.Hotel-Information)

![Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/1e301534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/db7f2529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/9edc3a0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/28500/28471/87852d13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Villa Castagnola

[](https://www.expedia.com/Lugano-Hotels-Grand-Hotel-Villa-Castagnola.h28471.Hotel-Information)

Cassarate

9.6/10

Exceptional

(395 reviews)

"It was a beautiful hotel with a lot of history. Very traditional, look with many amenities and great restaurant. The views from the room of Lake Lugano were breathtaking. I would strongly suggest this hotel if you’re staying in Lugano."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Avo

$593 nightly

$628 total

Mar 13 - Mar 14

Total with taxes and fees

[](https://www.expedia.com/Lugano-Hotels-Grand-Hotel-Villa-Castagnola.h28471.Hotel-Information)

![Executive Suite, Lake View (private terrace) | Terrace/patio](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/effee822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Lake View, Annex Building (in grotta) | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/1e108cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/99999c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/15000000/14840000/14837900/14837841/19debddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Lario Resort Mandello

[](https://www.expedia.com/Mandello-Del-Lario-Hotels-Villa-Lario-Resort-Mandello.h14837841.Hotel-Information)

Mandello del Lario

9.8/10

Exceptional

(38 reviews)

"Great well run resort"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

gordon

$623 nightly

$695 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Mandello-Del-Lario-Hotels-Villa-Lario-Resort-Mandello.h14837841.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/0c262dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/3dad6101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lake view](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/6db55adb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/25000000/24210000/24201200/24201147/72265d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Passalacqua

[](https://www.expedia.com/Moltrasio-Hotels-Passalacqua.h24201147.Hotel-Information)

Moltrasio

10/10

Exceptional

(18 reviews)

"Entire hotel is a 12/10 but add in that they have ALL the Dyson products in each room!!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

bernard

$1,745 nightly

$1,931 total

Apr 3 - Apr 4

Total with taxes and fees

[](https://www.expedia.com/Moltrasio-Hotels-Passalacqua.h24201147.Hotel-Information)

![Suite | Down comforters, in-room safe, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/b6eb0c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/3d91f596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sauna, steam room, massages](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/5a9dce7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/37000000/36840000/36832700/36832673/5daa0c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Campione

[](https://www.expedia.com/Campione-DItalia-Hotels-Grand-Hotel-Campione.h36832673.Hotel-Information)

Campione d'Italia

9.0/10

Wonderful

(167 reviews)

"Very good breakfast and welcoming atmosphere "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Ehab

$339 nightly

$373 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Campione-DItalia-Hotels-Grand-Hotel-Campione.h36832673.Hotel-Information)

![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/809690c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Porch](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/75a98b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite, 1 King Bed with Sofa bed, Terrace, Lake View | 1 bedroom, premium bedding, down comforters, Select Comfort beds](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/78f8b834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite, 1 King Bed with Sofa bed, Terrace, Lake View | Living area | LCD TV, pay movies](https://images.trvl-media.com/lodging/12000000/11790000/11780900/11780806/3f1048e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The View Lugano

[](https://www.expedia.com/Paradiso-Hotels-The-View-Lugano.h11780806.Hotel-Information)

Paradiso

9.6/10

Exceptional

(157 reviews)

"Wonderful hotel, can’t praise it enough. Look forward to our next stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jonathan

$645 nightly

$681 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Paradiso-Hotels-The-View-Lugano.h11780806.Hotel-Information)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/45ac639e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/988a8310.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/5c4f485b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/a3776c28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Swiss Diamond Hotel & SPA

[](https://www.expedia.com/Vico-Morcote-Hotels-Swiss-Diamond-Hotel.h972505.Hotel-Information)

Vico Morcote

9.0/10

Wonderful

(436 reviews)

"Beautiful property, very friendly and helpful staff. The breakfast buffet was excellent! We had a wonderful time."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Sabrina

$440 nightly

$468 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Vico-Morcote-Hotels-Swiss-Diamond-Hotel.h972505.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/6d77591e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/ea960e9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/w4386h6553x0y26-2c7d4562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Terrace, Lake View | Minibar, in-room safe, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/828f00e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Swiss Diamond Boutique Hotel La Romantica

[](https://www.expedia.com/Melide-Hotels-Swiss-Diamond-Boutique-Hotel-La-Romantica.h112636609.Hotel-Information)

Melide

9.8/10

Exceptional

(18 reviews)

"Beautiful location and friendly staffs are impressive. Would love to visit again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan

$504 nightly

$535 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Melide-Hotels-Swiss-Diamond-Boutique-Hotel-La-Romantica.h112636609.Hotel-Information)

![SOLE LUXURY ROOM WITH SPECTACULAR VIEW | Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/104000000/103950000/103941400/103941364/2189788c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/104000000/103950000/103941400/103941364/594b0335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/104000000/103950000/103941400/103941364/c349bb72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![SOLE LUXURY ROOM WITH SPECTACULAR VIEW | Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/104000000/103950000/103941400/103941364/1e2dcff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nuvole Garden Hotel

[](https://www.expedia.com/Brunate-Hotels-Nuvole-Garden-Hotel.h103941364.Hotel-Information)

Brunate

8.4/10

Very Good

(8 reviews)

"Amazing room, amazing views and amazing staff... 100% going back!"

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Richard

$756 nightly

$843 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Brunate-Hotels-Nuvole-Garden-Hotel.h103941364.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/8e70820d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio, 1 King Bed, Non Smoking, Mountain View | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/14b67def.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Non Smoking, Mountain View | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/487154f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, City View | Living area | 55-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/77000000/76580000/76573600/76573521/d0c12bb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Swiss Hotel Apartments - Lugano

[](https://www.expedia.com/Lugano-Hotels-Swiss-Hotel-Apartments-Lugano.h76573521.Hotel-Information)

Lugano City-Centre

8.4/10

Very Good

(17 reviews)

"Great property and location. Apartments were very clean and had all the amenities you would need. Communication with office staff was great and they were always available if needed. Would definitely stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Diana

[](https://www.expedia.com/Lugano-Hotels-Swiss-Hotel-Apartments-Lugano.h76573521.Hotel-Information)

![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/51ee9c30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/3e73da6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/f61899c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Lake View | Balcony view](https://images.trvl-media.com/lodging/1000000/530000/522900/522870/e463ce03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Eden Roc

[](https://www.expedia.com/Ascona-Hotels-Hotel-Eden-Roc.h522870.Hotel-Information)

Ascona

9.4/10

Exceptional

(129 reviews)

"Super Hotel! "

![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg)

Stephan

$779 nightly

$820 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Ascona-Hotels-Hotel-Eden-Roc.h522870.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/47000000/46170000/46161300/46161238/fc315eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor spa tub](https://images.trvl-media.com/lodging/47000000/46170000/46161300/46161238/b8500682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Lake View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/47000000/46170000/46161300/46161238/ffbff3c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Lake View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/47000000/46170000/46161300/46161238/ad9bfb07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bianca Relais - by R Collection Hotels

[](https://www.expedia.com/Oggiono-Hotels-Bianca-Relais.h46161238.Hotel-Information)

Oggiono

9.8/10

Exceptional

(50 reviews)

"simple n modern design beautiful lakeview"

![Hong Kong SAR China](https://a.travel-assets.com/egds/marks/flags/hk.svg)

Po Mei

$263 nightly

$290 total

Mar 24 - Mar 25

Total with taxes and fees

[](https://www.expedia.com/Oggiono-Hotels-Bianca-Relais.h46161238.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mendrisio.

![Hotel Osteria della Pista](https://images.trvl-media.com/lodging/3000000/2530000/2523100/2523034/06441981_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Osteria della Pista

Via Verbano 1 Casorate Sempione VA

$102 nightly

$113 total

Mar 13 - Mar 14

Total with taxes and fees

9.4/10 Exceptional! (1,247 reviews)

[](https://expedia.com/Milan-Hotels-Hotel-Osteria-Della-Pista.h2523034.Hotel-Information)

![Idea Hotel Milano Malpensa Airport](https://images.trvl-media.com/lodging/4000000/3980000/3970100/3970024/1f8bad56_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Idea Hotel Milano Malpensa Airport

Via Della Chiesa, 27 Somma Lombardo VA

$94 nightly

$108 total

Mar 19 - Mar 20

Total with taxes and fees

7.4/10 Good! (1,003 reviews)

[](https://expedia.com/Milan-Hotels-Idea-Hotel-Milano-Malpensa-Airport.h3970024.Hotel-Information)

![Crowne Plaza Milan - Malpensa Airport by IHG](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427867/6556f277_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Crowne Plaza Milan - Malpensa Airport by IHG

Via Arturo Ferrarin, 7 Somma Lombardo VA

$101 nightly

$116 total

Mar 30 - Mar 31

Total with taxes and fees

8.4/10 Very Good! (1,006 reviews)

[](https://expedia.com/Milan-Hotels-Crowne-Plaza-Malpensa-Airport.h1427867.Hotel-Information)

Still don't see what you're looking for?

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[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F6%2F2026&endDate=3%2F7%2F2026&regionId=6023188&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F6%2F2026&endDate=3%2F7%2F2026&regionId=6023188&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F6%2F2026&endDate=3%2F7%2F2026&regionId=6023188&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F6%2F2026&endDate=3%2F7%2F2026&regionId=6023188&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F6%2F2026&endDate=3%2F7%2F2026&regionId=6023188&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Mendrisio

Tucked between Lake Lugano and Generoso Mount, this charming town invites you to explore its cultural treasures at Museum d'Art and Galleria Baumgartner. Bargain hunters flock to FoxTown Factory Stores while nature lovers can discover the UNESCO-listed Monte San Giorgio with its remarkable fossil deposits.

[See all hotels in Mendrisio](https://www.expedia.com/Hotel-Search?startDate=2026-03-19&endDate=2026-03-20&adults=2&regionId=6023188)

![Panoramic aerial view of a Swiss city. Mendrisio with to the right the church of Saints Cosmas and Damian, Switzerland](https://images.trvl-media.com/place/6023188/884b6b7d-a4b6-4265-a0af-bbf91c4a7cd9.jpg?impolicy=fcrop&w=900&h=296&p=1&q=high)

## Top Mendrisio Hotel Reviews

![Grand Hotel Villa Serbelloni](https://images.trvl-media.com/lodging/1000000/910000/903800/903773/0216c45f_y.jpg)

### Grand Hotel Villa Serbelloni

10/10 Excellent

"The staff were wonderful and the hotel was impeccable. All amenities were extremely thoughtful."

[](https://expedia.com/Bellagio-Hotels-Grand-Hotel-Villa-Serbelloni.h903773.Hotel-Information)

![Grand Hotel Tremezzo](https://images.trvl-media.com/lodging/59000000/58950000/58946700/58946683/a1226752_y.jpg)

### Grand Hotel Tremezzo

8/10 Good

"Yes … very"

[](https://expedia.com/Tremezzina-Hotels-Grand-Hotel-Tremezzo.h58946683.Hotel-Information)

## Find out more about Mendrisio

Treat yourself on your next getaway. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Mendrisio so popular in the last year. There's no reason to delay a getaway to Mendrisio any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Mendrisio and get ready to be pampered like never before. Don't wait any longer!

### 5-Star Hotels in Mendrisio

You'll have a wonderful time at one of these 5-star hotels. Michelin-starred restaurants, concierges, and in-room massages are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? A full-body massage to help your cares fall away? A concierge to help you pick out your next adventure? Beautiful furniture, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. 

Ready for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mendrisio are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. 

### Make Your Escape

The results are in, and Mendrisio 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of Expedia's Mendrisio 5-star hotels today and soothe yourself in total tranquility tomorrow.

## Frequently asked questions

### What are the best 5-star hotels in Mendrisio?

### How much does it cost to stay in a 5-star hotel in Mendrisio?

> - Search for the lowest price per night from $108

### What makes a hotel 5 stars in Mendrisio?

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