A building with a red-tiled roof, palm trees, and a flagpole with an American flag.

Find 5 Star Hotels in Mesa, AZ from $122

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Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mesa.
Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ

5643 East Longbow Pkwy Mesa AZ
$138 nightly
The price is $157 total per night from Nov 23 to Nov 24
$157 total
Nov 23 - Nov 24
Total with taxes and fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mesa

The Sonoran Desert blooms spectacularly around ancient cliff dwellings and museums celebrating native cultures at Mesa's edge. Kayak the Salt River for wild horse sightings or explore downtown's food halls where local chefs serve prickly pear ice cream after desert hikes.

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The Arizona Museum of Natural History with a large dinosaur mural on the building.

Top Mesa Hotel Reviews

Find out more about Mesa

Why not ask for complete opulence on your excursion to Mesa? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Mesa so popular in the last year. There's no reason to delay a getaway to Mesa any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Mesa and get ready to be pampered like never before. Don't wait any longer!

Book the Best Mesa 5-Star Hotels

You can expect superior customer service from your hotel. Excellent customer care, luxurious bedding, and rejuvenating spa offerings are all on offer. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Mesa offer great customer service, averaging 3.7 in our ranking system, giving you a lot to look forward to. What kind of amenities will make your stay a wonderful one? A deep-tissue massage to help your cares fall away? A concierge to help you suggest the next attraction to visit? Fluffy down pillows, lip-smacking main courses, and even a hot tub in the bathroom...these hotels will leave you amazed. Want to see for yourself? Then explore the 1,363 reviews various guests have left on Expedia and get to know these places.

Yearning for experiences outside your hotel room? We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Mesa are waiting for you to relax after a busy day.

Your Getaway Starts Today

The results are in, and Mesa 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of our Mesa 5-star hotels today and decompress in complete comfort tomorrow.

Frequently asked questions

What are the best 5-star hotels in Mesa?
Treat yourself to a luxurious stay at The Canyon Suites at The Phoenician, Luxury Collection. This is among the most popular 5-star hotels in Mesa based on reviews by Expedia customers. From its plush guest rooms to its premium amenities and services, you can rely on the highest standard of excellence.
How much does it cost to stay in a 5-star hotel in Mesa?
How much you pay for a 5-star hotel in Mesa depends on factors such as when you plan to travel and the length of your getaway. A top tip for landing an awesome deal? Use our pricing filters to check out all of the available options for your chosen dates.

  • Search for the lowest price per night from $122

What makes a hotel 5 stars in Mesa?
Flawless guest service is the foundation of every 5-star hotel in Mesa. From the minute you step through the door, staff ensure your every need is met, whether arranging valet parking or providing a turn-down service. Also, hotels must feature superior amenities to be considered for a 5-star rating. These can include luxury baths, a wellness center, pools, gourmet kitchens and knowledgeable concierge.

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