Rome City Centre Vacations from $749
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Your Rome City Centre Vacation
If you're wanting a picturesque escape, our Rome City Centre vacation packages are just what you need. Whether you're searching for shopping, markets or history, this neighborhood has something on offer for everyone. Some top nearby attractions to check out during your trip to Rome City Centre include St. Peters Basilica, Roman Forum and Pantheon. Whatever your travel goals or the size of your budget, booking the ultimate Rome City Centre vacation is a cinch with Expedia.
The Latest Rome City Centre Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Where to stay in Rome City Centre
Find the best Rome City Centre areas and neighborhoods for the activities you enjoy most. Learn more about Rome City Centre
Rome Historic Centre
Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.
Rome City Centre Hotel Deals
Hotel Quirinale
Via Nazionale 7 Rome RM
$142 nightly
The price is $173 total per night from Dec 15 to Dec 16
$173 total
Dec 15 - Dec 16
Total with taxes and fees
8.8/10 Excellent! (1,931 reviews)
"Loved the property and breakfast."
Reviewed on Nov 12, 2026
Aria Palace by OMNIA Hotels
Via Torino, 127 Rome RM
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $190 total per night from Nov 29 to Nov 30
$190 total
Nov 29 - Nov 30
Total with taxes and fees
Marcella Royal Hotel - Rooftop Garden
Via Flavia 106 Rome RM
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $136 total per night from Dec 15 to Dec 16
$136 total
Dec 15 - Dec 16
Total with taxes and fees
9.2/10 Wonderful! (1,004 reviews)
"Everything was exceptional especially the staff!"
Reviewed on Nov 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Rome City Centre attractions
Things to do
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
$26
per adult
84% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
$38
per adult
90% of travellers recommend
Rome 3 in 1 Cooking Class: Fettuccine, Ravioli & Tiramisu
$58
per adult
98% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.