Rome City Centre Vacations from $730

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Your Rome City Centre Vacation

If you're wanting a picturesque escape, our Rome City Centre vacation packages are just what you need. Whether you're searching for shopping, markets or history, this neighborhood has something on offer for everyone. Some top nearby attractions to check out during your trip to Rome City Centre include St. Peters Basilica, Roman Forum and Pantheon. Whatever your travel goals or the size of your budget, booking the ultimate Rome City Centre vacation is a cinch with Expedia.

The Latest Rome City Centre Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Il Campo Marzio
Hotel Genio
Hotel Scenario
Grand Hotel Gianicolo
Rome Times Hotel

Where to stay in Rome City Centre

Find the best Rome City Centre areas and neighborhoods for the activities you enjoy most. Learn more about Rome City Centre

Rome City Centre Hotel Deals

Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
$150 nightly
The price is $182 total per night from Dec 8 to Dec 9
$182 total
Dec 8 - Dec 9
Total with taxes and fees
8.8/10 Excellent! (1,927 reviews)
"Old Hotel that is well maintained. Room was kind of small but bathroom was nice. You won't get wash cloths with your bath linen, so take some disposable ones. Morning breakfast buffet was excellent and the courtyard setting in the restaurant is peaceful. Restaurant food is good, not excellent but ..."

Reviewed on Nov 10, 2026

Hotel Quirinale
Aria Palace by OMNIA Hotels

Aria Palace by OMNIA Hotels

4 out of 5
Via Torino, 127 Rome RM
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $193 total per night from Nov 29 to Nov 30
$193 total
Nov 29 - Nov 30
Total with taxes and fees
Aria Palace by OMNIA Hotels
Marcella Royal Hotel - Rooftop Garden

Marcella Royal Hotel - Rooftop Garden

4 out of 5
Via Flavia 106 Rome RM
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $162 total per night from Dec 1 to Dec 2
$162 total
Dec 1 - Dec 2
Total with taxes and fees
9.2/10 Wonderful! (1,004 reviews)
"We loved the location! Felt safe walking around in the evenings. The breakfast was nice before full days of sightseeing. The staff were extremely helpful including Mauro helping with recommendations and taxis. Will definitely stay again!"

Reviewed on Nov 9, 2026

Marcella Royal Hotel - Rooftop Garden
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Rome City Centre attractions

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.