Title: Visit Adrian: 2026 Travel Guide for Adrian, Texas | Expedia.com [Hotels in Adrian](https://expedia.com/Adrian-Hotels.d3000422512.Travel-Guide-Hotels)[Vacation Rentals in Adrian](https://expedia.com/Adrian-Vacation-Rentals.d3000422512.Travel-Guide-VacationRentals)[Flights to Adrian](https://expedia.com/Cheap-Flights-To-Adrian.d3000422512.Travel-Guide-Flights)[Car Rentals in Adrian](https://expedia.com/Car-Rentals-In-Adrian.d3000422512.Car-Rental-Guide)[Adrian Vacation Packages](https://expedia.com/Adrian.d3000422512.Destination-Travel-Guides) # Adrian, TX ## Travel Guide ![Route 66 midpoint sign](https://images.trvl-media.com/place/3000422512/2d6ba6c5-60b8-4e08-9416-59acd9115cc9.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The midway point along Route 66](https://images.trvl-media.com/place/3000422512/f847379e-fdc9-4a2f-bb9e-322b1c5ac23c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Midway point of historic Route 66 between Chicago and Los Angeles (both 1139 miles) in Adrian, Texas](https://images.trvl-media.com/place/3000422512/e4da126f-91af-4dce-a437-101916cb520a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Adrian is just off Interstate 40. It is also the midpoint of the historic Route 66. From here it is 1139 miles East to Chicago and 1139 miles West to Los Angeles. There is also Midpoint Cafe, a 50's style diner with a great burger and fries. However, if you stop you have to ask about their "Ugly Pie."](https://images.trvl-media.com/place/3000422512/a77a6e86-60b8-4227-9215-9b9641bf45f7.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Rte 55](https://images.trvl-media.com/place/3000422512/beffa175-e635-4d7f-abc9-5b81547afe24.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Adrian Things to do - Adrian Hotel Deals - Vacation Rentals in Adrian ![Capital O Route 66 Country Inn Vega Tx](https://images.trvl-media.com/lodging/1000000/20000/15400/15301/208d29ca_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Capital O Route 66 Country Inn Vega Tx 1800 West Vega Boulevard Vega TX $77 nightly $85 total Mar 22 - Mar 23 Total with taxes and fees Book a stay at this business-friendly hotel in Vega. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ... 7.8/10 Good! (365 reviews) Great people, older rt 66 motel, clean, large room, comfy bed. Great stop for us on way home. Reviewed on Mar 4, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=15301&PinnedHotelID=15301&HadPinnedHotel=true®ionId=3000422512) ![Days Inn by Wyndham Vega TX](https://images.trvl-media.com/lodging/1000000/130000/120700/120685/7aa63246_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Days Inn by Wyndham Vega TX 1005 S Main St Vega TX Fully refundableReserve now, pay when you stay $77 nightly $86 total Apr 5 - Apr 6 Total with taxes and fees Stay at this hotel in Vega. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Magnolia Gas Station is located nearby. 6.8/10 (403 reviews) Hotel appeared run down. Room had no amenities. In morning coffee was lukewarm and breakfast was ridiculous. Reviewed on Feb 25, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=120685&PinnedHotelID=120685&HadPinnedHotel=true®ionId=3000422512) ![Bonanza Motel Vega](https://images.trvl-media.com/lodging/17000000/16790000/16781500/16781444/91799a74_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Bonanza Motel Vega 607 Vega Blvd Vega TX $62 nightly $69 total Mar 22 - Mar 23 Total with taxes and fees Stay at this motel in Vega. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Magnolia Gas Station is located nearby. [](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=16781444&PinnedHotelID=16781444&HadPinnedHotel=true®ionId=3000422512) [See all 21 properties in Adrian](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026®ionId=3000422512) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Hotel Zaza Houston Museum District](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/0f950f88_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Zaza Houston Museum District 5701 Main Street Houston TX Book a stay at this luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ... 9/10 Wonderful! (1,923 reviews) Very Beautiful and welcoming! Reviewed on Mar 19, 2026 [](https://expedia.com/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![Casa De La Sirena--Beachfront Retreat in Spanish Grant!](https://images.trvl-media.com/lodging/106000000/105950000/105943900/105943856/45b39f6a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Casa De La Sirena--Beachfront Retreat in Spanish Grant! Galveston TX Book a stay at this beach vacation home in Galveston. Enjoy a beach locale, laundry facilities, and patios. Popular attractions Galveston Island Beaches and ... 9.6/10 Exceptional! (74 reviews) Everything was great! Reviewed on Feb 8, 2026 [](https://expedia.com/Galveston-Hotels-Casa-De-La-Sirena-Beachfront-Retreat-In-Spanish-Grant.h105943856.Hotel-Information) ![NEW UPDATES! Top Flr Sunrise-Ocean View, Prvt Beach Access, Pool, W&D, Parking](https://images.trvl-media.com/lodging/43000000/42810000/42809900/42809835/7362c431_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### NEW UPDATES! Top Flr Sunrise-Ocean View, Prvt Beach Access, Pool, W&D, Parking Galveston TX Book a stay at this beach condo in Galveston. Enjoy free WiFi, a beach locale, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular ... 10/10 Exceptional! (252 reviews) Beach access is perfect! Reviewed on Mar 16, 2026 [](https://expedia.com/Galveston-Hotels-BeachfrontTop-FloorSunriseOcean-ViewHeated-Pool2-Hot-TubsBeach-Access.h42809835.Hotel-Information) [See all 81,519 properties in Texas](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=245&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Adrian hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000422512&startDate=2026-03-21&endDate=2026-03-22)[Mar 21 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000422512&startDate=2026-03-21&endDate=2026-03-22) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000422512&startDate=2026-03-22&endDate=2026-03-23)[Mar 22 - Mar 23](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000422512&startDate=2026-03-22&endDate=2026-03-23) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000422512&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000422512&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) ### Popular places to visit #### Midway Point of Route 66 You can find out about the history of Adrian with a stop at Midway Point of Route 66\. Discover the area's museums and shops. [](https://expedia.com/Midway-Point-Of-Route-66-Adrian.d938001438370816000.Vacation-Attraction) ## Cities near Adrian ![Cow at sunset](https://images.trvl-media.com/place/10261/a690a778-497b-4e30-98b3-0342c536639c.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Vega ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Oldham County Hotels ](https://www.expedia.com/Destinations-In-Oldham-County.d553248635976434152.Hotel-Destinations) - [Hotels near Magnolia Gas Station ](https://www.expedia.com/Magnolia-Gas-Station-Hotels.0-l553248621561866775-0.Travel-Guide-Filter-Hotels) - [Vega Hotels ](https://www.expedia.com/Vega-Hotels.d10261.Travel-Guide-Hotels) - [Pet-Friendly Hotels in Vega ](https://www.expedia.com/Vega-Hotels-Pet-Friendly-Hotel.0-0-d10261-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Restaurants in Vega ](https://www.expedia.com/Vega-Hotels-Hotels-With-Restaurants.0-0-d10261-tHotelswithRestaurants.Travel-Guide-Filter-Hotels) - 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[Flights from Oldham County ](https://www.expedia.com/lp/flights/553248635976434152/flights-from-oldham-county) - [Flights to Vega ](https://www.expedia.com/Cheap-Flights-To-Vega.d10261.Travel-Guide-Flights) - [Flights from Vega ](https://www.expedia.com/lp/flights/10261/flights-from-vega) - [Flights from Deaf Smith County ](https://www.expedia.com/lp/flights/553248635976433441/flights-from-deaf-smith-county) - [Flights from Channing ](https://www.expedia.com/lp/flights/553248634998593849/flights-from-channing) - [Flights to Hereford ](https://www.expedia.com/Cheap-Flights-To-Hereford.d8336.Travel-Guide-Flights) - [Flights from Hereford ](https://www.expedia.com/lp/flights/8336/flights-from-hereford) - [Flights from Hartley County ](https://www.expedia.com/lp/flights/553248635976433674/flights-from-hartley-county) - [Visit Vega ](https://www.expedia.com/Vega.dx10261) - [Vega Vacations ](https://www.expedia.com/Vega.d10261.Destination-Travel-Guides) - [Visit Wildorado ](https://www.expedia.com/Wildorado.dx3000459391) - 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[Car rentals near Texas Tech University Health Sciences Center ](https://www.expedia.com/Car-Rentals-In-Texas-Tech-University-Health-Sciences-Center.d6080885.Car-Rental-Guide) - [Hereford Vacation Rentals ](https://www.expedia.com/Hereford-Vacation-Rentals.d8336.Travel-Guide-VacationRentals) - Cities near Adrian - Places of interest [Vega](https://expedia.com/Vega.dx10261) - [Magnolia Gas Station ](https://expedia.com/Magnolia-Gas-Station-Vega.d553248621561866775.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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