Find All St. Charles Hotels
Upfront pricingOur total price for your stay includes taxes and fees
Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
Be pickySearch almost a million properties worldwide
Find All St. Charles Hotels
We have found 501 St. Charles Hotels
- White Valley Motel
- Kahler Grand Hotel
- Kahler Inn and Suites - Mayo Clinic Area
- Hotel Indigo Rochester – Mayo Clinic Area by IHG
- Hampton Inn Rochester-South
- EVEN Hotel Rochester - Mayo Clinic Area by IHG
- Hyatt House Rochester/Mayo Clinic Area
- Aspen Suites
- AmericInn by Wyndham Rochester Near Mayo Clinic
- Spark by Hilton Rochester South
- La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
- Holiday Inn Express Rochester South - Mayo Area by IHG
- SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
- Brentwood Inn & Suites
- Staybridge Suites Rochester - Mayo Clinic Area by IHG
- Med City Inn & Suites - Mayo Clinic Area
- Home2 Suites by Hilton Rochester Mayo Clinic Area
- Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
- Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
- Hampton Inn & Suites Rochester-North
- Holiday Inn Express & Suites Winona by IHG
- AmericInn by Wyndham Winona
- Hilton Rochester Mayo Clinic Area
- Hilton Garden Inn Rochester Downtown, MN
- Residence Inn by Marriott Rochester Mayo Clinic Area South
- Aspen Select
- Marriott Rochester Mayo Clinic
- Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
- Country Inn & Suites by Radisson, Rochester, MN
- Country Inn & Suites Rochester South Mayo Clinic
- Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
- Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
- Econo Lodge Mayo Clinic Area
- Express Suites Riverport Inn & Suites
- Candlewood Suites Rochester Mayo Clinic Area by IHG
- Sleep Inn & Suites West-Near Medical Center
- TownePlace Suites by Marriott Rochester Mayo Clinic Area
- Super 8 by Wyndham Rochester Mayo Clinic Area
- Quality Inn near Medical Center
- Staybridge Suites Rochester - Commerce Dr NW by IHG
- Super 8 by Wyndham Winona MN
- TownePlace Suites by Marriott Rochester
- Motel 6 Rochester, MN
- The Plaza Hotel & Suites Winona
- Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
- Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
- Red Carpet Inn Rochester
- Quality Inn & Suites Mayo Clinic Area
- Days Inn by Wyndham Winona
- Comfort Inn & Suites West - Medical Center
- AmericInn by Wyndham Rochester
- Baymont by Wyndham Rochester Mayo Clinic Area
- Extended Stay America Suites Rochester North
- Fairfield Inn & Suites by Marriott Winona
- Residence Inn by Marriott Rochester Mayo Clinic Area
- MainStay Suites Rochester South Mayo Clinic
- Alexander Mansion Bed and Breakfast
- The Towers At Kahler Grand Hotel
- Stone Mill Hotel & Suites
- Country Trails Inn & Suites
- The Wen Inn formerly Andor Wenneson
- Americinn By Wyndham Wabasha
- Carriage House B&B
- Quiet, comfortable bed & breakfast in a gorgeous rural setting!
- Charming farmhouse with 4 bedrooms and WiFi, AC near Spring Valley
- 3 Peaks Farmhouse- Beautiful Remodel with Scenic Views + Root River Trail access
- Logde sleeps 11 ...set up for exploring the Mississippi River or Driftless Area.
- Rabbit Hole Retreat, River on Property, Adults Only, No Pets, Peace and Quiet!
- Riverview Apartment - River Road Historic Home
- The Wen Inn - 5 Suites Sleeps 14+ Host Events
- Country School Guest House, New Construction
- Green Gables Inn
- Birch Hill Suite Rochester – Med City
- Schmidt Farm: an interactive farm experience bordering Forestville State Park
- Tiny Treehouse Cabin Retreat, Riverside, Adults Only, No Pets, Peace and Quiet!
- Sunset Room Retreat, River on Property, Adults Only, No Pets, Peace and Quiet!
- Sunrise Suite Retreat, River on Property, Adults Only, No Pets, Peace and Quiet!
- Room A1 at Green Gables Inn - Garden Rooms on the Riverside in Lanesboro, MN
- Iron Horse Outfitters and Inn
Let Expedia take you to the best Hotels in St. Charles. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.