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Find hotels in Cape Girardeau, MO from $66

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Compare 157 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1001)
"Great stay!!"
The price is $102
includes taxes & fees
$90 per night
May 4 - May 5
Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview
Grand Riverview Two Queen Room | Premium bedding, pillowtop beds, in-room safe, desk

The Riverview

2.0 star property
9.2 out of 10, Wonderful, (240)
"Great Hotel"
The price is $121
includes taxes & fees
$107 per night
May 5 - May 6
The Riverview
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"Will definitely stay there again!!"
The price is $118
includes taxes & fees
$105 per night
May 30 - May 31
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (925)
"Always The best hotel "
The price is $112
includes taxes & fees
$99 per night
May 6 - May 7
Drury Inn & Suites Cape Girardeau
Candlewood Suites Cape Girardeau by IHG
Exterior

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very Good, (775)
"Located close to food and access to the golf course. Doesn’t provide breakfast but reasonable priced which offset continental breakfast. Clean and well maintained. I would stay her again "
The price is $103
includes taxes & fees
$86 per night
May 12 - May 13
Candlewood Suites Cape Girardeau by IHG
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (102)
"Great place to stay"
The price is $105
includes taxes & fees
$93 per night
May 8 - May 9
Fairfield Inn & Suites by Marriott Cape Girardeau
Courtyard by Marriott Cape Girardeau Downtown
Lobby

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (411)
"I love the Hotel check in was a breeze. The staff were friendly ,helpful and pr"
The price is $147
includes taxes & fees
$130 per night
May 25 - May 26
Courtyard by Marriott Cape Girardeau Downtown
Hampton Inn Cape Girardeau I 55 East
Courtyard

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (705)
"We stay here each time we go around Missouri "
The price is $124
includes taxes & fees
$110 per night
May 25 - May 26
Hampton Inn Cape Girardeau I 55 East
Tru By Hilton Cape Girardeau
Room

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (10)
"Exceptionally clean and the staff was absolutely wonderful."
The price is $115
includes taxes & fees
$101 per night
May 6 - May 7
Tru By Hilton Cape Girardeau
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Nice place, would stay here again "
The price is $81
includes taxes & fees
$72 per night
May 5 - May 6
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau Near the Medical Center
Seasonal outdoor pool

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Continental breakfast where the hostess made the waffles for you; friendly staff."
The price is $66
includes taxes & fees
$58 per night
May 4 - May 5
Pear Tree Inn Cape Girardeau Near the Medical Center
Quality Inn
Lobby

Quality Inn

2.5 star property
7.0 out of 10, Good, (569)
"Love it very clean and very quiet love the experience"
The price is $68
includes taxes & fees
$60 per night
May 6 - May 7
Quality Inn
Rockwood Inn
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi

Rockwood Inn

2.0 star property
9.8 out of 10, Exceptional, (8)
"Close to downtown and the Mississippi River area "
The price is $170
includes taxes & fees
$150 per night
May 7 - May 8
Rockwood Inn
Town House Inn Cape Giradreau
Desk, free WiFi

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (181)
"Easy to get in and out "
The price is $74
includes taxes & fees
$66 per night
May 1 - May 2
Town House Inn Cape Giradreau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
9.0 out of 10, Wonderful, (542)
"Quiet, clean, cozy, reasonably priced!"
The price is $87
includes taxes & fees
$81 per night
May 4 - May 5
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (701)
"Our room was clean and the staff was friendly and helpful. Overall satisfactory condition and we would stay here again. "
The price is $94
includes taxes & fees
$87 per night
May 1 - May 2
Comfort Suites Jackson-Cape Girardeau
Drury Inn & Suites Jackson MO
Lobby

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1002)
"Pam who took care of the breakfast was so nice! Lovely place, clean, and great breakfast, definitely recommend!"
The price is $95
includes taxes & fees
$90 per night
May 4 - May 5
Drury Inn & Suites Jackson MO
Davie School Inn
Gold Suite | View from room

Davie School Inn

4.0 star property
10.0 out of 10, Exceptional, (47)
"A very unique place to stay, fun to look around at all the old school items!! The room was unique and very spacious.. great bed and hostess!!! Very walkable to restaurants and stores.. "
The price is $177
includes taxes & fees
$159 per night
May 12 - May 13
Davie School Inn
Hotel 7 Inn Anna
Basic Room, 1 King Bed | Individually decorated, individually furnished, desk, free WiFi

Hotel 7 Inn Anna

2.5 star property
6.6 out of 10, (197)
"Good service "
The price is $80
includes taxes & fees
$72 per night
May 27 - May 28
Hotel 7 Inn Anna
Regency Inn
Reception

Regency Inn

2.0 star property
The price is $106
includes taxes & fees
$99 per night
May 21 - May 22
Regency Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Cape Girardeau

Trip time! Discover the riverfront, history, and local cuisine in Cape Girardeau.

See all hotels in Cape Girardeau
The Bar - this was one location Gone Girl was filmed at!
Photo by Skyy
Open Photo by Skyy

Find out more about Cape Girardeau

Find out more about Cape Girardeau

Top reasons to visit Cape Girardeau

  • Scenic Outdoor Adventures: Cape Girardeau features beautiful parks and natural areas like the Trail of Tears State Park for hiking and relaxation.
  • Rich Historical Sites: Explore local history at the Cape Girardeau History Museum and the vibrant Southeast Missouri State University.
  • Family-Friendly Activities: Enjoy the Cape Riverfront, offering various recreational options for families and children.
  • Gaming and Entertainment: Experience the thrill of gaming at local casinos for an exciting night out.
  • Diverse Accommodation Options: Choose from a range of hotels to suit every traveler's budget and needs.

Find great hotels in Cape Girardeau

Discover a diverse selection of hotels in Cape Girardeau, Missouri, catering to every traveler's needs, from budget-friendly motels to comfortable 4-star accommodations. Whether you're on a family vacation, a business trip, or traveling with pets, you'll find a variety of options that promise a pleasant stay. Explore popular hotels and suites that provide essential services and facilities for an enjoyable experience in this charming city.

  • Auburn Place Hotel And Suites: Experience a blend of comfort and convenience at Auburn Place Hotel And Suites, perfect for business travelers and pet owners alike. This hotel offers a professional atmosphere with a well-equipped Business Center, 24-hour access, and flexible meeting rooms to cater to your corporate needs. For those traveling with furry companions, the hotel welcomes pets with specific restrictions, ensuring your beloved animal can join you on your journey. Enjoy a relaxing stay with thoughtful amenities designed to make your visit both productive and enjoyable.
  • Pear Tree Inn Cape Girardeau West: Pear Tree Inn Cape Girardeau West is an ideal choice for families, business travelers, and pet lovers. The hotel features a welcoming environment with a 24-hour Business Center and free cribs for families traveling with infants, making it a practical option for all. Pets are welcome here, too, with specific guidelines to ensure a comfortable experience for everyone. This hotel combines family-friendly amenities with a focus on business convenience, allowing you to balance work and leisure seamlessly.
  • Drury Plaza Hotel Cape Girardeau Conference Center: The Drury Plaza Hotel Cape Girardeau Conference Center provides a sophisticated yet family-oriented atmosphere, making it perfect for both leisure and business travelers. With multiple meeting rooms and a dedicated conference center, this hotel is equipped to handle your business needs effectively. Families will appreciate the inclusion of free cribs and pet-friendly policies, ensuring that no family member is left behind. The hotel’s blend of modern amenities and warm hospitality sets it apart, making your stay both productive and memorable.

Discover the best areas to stay in Cape Girardeau

Experience the charm of Cape Girardeau, Missouri, where outdoor adventures and historical sites await. Explore family-friendly activities like the scenic Cape Riverfront and the fascinating Southeast Missouri State University, or immerse yourself in local history at the Cape Girardeau History Museum. Nearby, enjoy the friendly atmosphere while discovering the beauty of nature at Trail of Tears State Park. Whether you're seeking adventure or relaxation, Cape Girardeau offers a delightful blend of experiences for every traveler.

  • Jackson: Located approximately 10 miles from Cape Girardeau, Jackson is a charming city that offers a variety of outdoor adventures and scenic spots. Known for its recreational areas, Jackson attracts visitors year-round, with peak travel times in April, July, and September. You can explore local landmarks such as the national park and nearby lakes, making it a fantastic destination for nature enthusiasts. The city also features a casino, providing entertainment options for those looking to unwind after a day of exploration.
  • Sikeston: About 30 miles from Cape Girardeau, Sikeston is a vibrant city that appeals to those seeking outdoor experiences and romantic getaways. With traveler arrivals peaking in April and during the summer months of June and July, Sikeston offers a welcoming atmosphere year-round. Visitors can enjoy recreational areas and an arena entertainment facility, along with the excitement of a casino. The close proximity to stunning lakes and national parks makes Sikeston a perfect spot for adventure seekers and couples alike.
  • Anna: Situated around 18 miles from Cape Girardeau, Anna is a delightful city known for its outdoor activities and adventurous spirit. Visitors flock to Anna, especially in April and from July to August, to enjoy the natural beauty of the area. With access to national parks, forests, and serene lakes, Anna is a haven for those who love camping and exploring the great outdoors. The city features various recreational areas that cater to families and outdoor enthusiasts, ensuring a memorable experience for all.

Find the best attractions in Cape Girardeau

Cape Girardeau offers a delightful blend of outdoor adventures and cultural experiences perfect for family trips. Visitors can explore scenic national and state parks, as well as urban parks that provide ample opportunities for relaxation and exploration. With a variety of attractions catering to nature lovers and culture enthusiasts alike, your vacation in Cape Girardeau is sure to be memorable and enjoyable.

  • Southeast Missouri State University: Immerse yourself in the vibrant culture of Southeast Missouri State University, where you'll find a lively campus atmosphere with beautiful architecture, art exhibits, and engaging student activities. Explore its rich history and diverse academic programs.
  • Riverfront Bridge Park: Enjoy quality family time at Riverfront Bridge Park, a scenic outdoor space perfect for picnics, walking, and biking. With its eco-friendly design, this park provides stunning views of the river and is a great spot for relaxation and recreation.
  • Trail of Tears State Park: Experience adventure at Trail of Tears State Park, just 10 miles from Cape Girardeau. Hike through beautiful landscapes, witness breathtaking scenery, and connect with nature in this historic site dedicated to the Native American experience.

Booking tips and Expedia advantages for Cape Girardeau

To save money on your trip to Cape Girardeau, consider visiting during the off-peak months of July and November to December for lower hotel rates. Utilize public transport options or opt for walking to explore the city affordably. Take advantage of free activities like Isle Casino and Trail of Tears State Park. Use Expedia to find and compare the best hotel deals, and consider bundling your hotel stay with flights and activities for extra savings. Joining Expedia's One Key membership can also provide exclusive discounts and cash back on future bookings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Cape Girardeau are July and November to December, where the prices are slightly lower. This is in comparison to February to April, where prices are slightly higher.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your options based on your budget, desired location, and preferred type of accommodation. To find the most affordable prices and offers, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Cape Girardeau with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in Cape Girardeau

Cape Girardeau offers a delightful blend of outdoor adventures and cultural experiences perfect for family trips. Visitors can explore scenic national and state parks, as well as urban parks that provide ample opportunities for relaxation and exploration. With a variety of attractions catering to nature lovers and culture enthusiasts alike, your vacation in Cape Girardeau is sure to be memorable and enjoyable.

  • Southeast Missouri State University: Immerse yourself in the vibrant culture of Southeast Missouri State University, where you'll find a lively campus atmosphere with beautiful architecture, art exhibits, and engaging student activities. Explore its rich history and diverse academic programs.
  • Riverfront Bridge Park: Enjoy quality family time at Riverfront Bridge Park, a scenic outdoor space perfect for picnics, walking, and biking. With its eco-friendly design, this park provides stunning views of the river and is a great spot for relaxation and recreation.
  • Trail of Tears State Park: Experience adventure at Trail of Tears State Park, just 10 miles from Cape Girardeau. Hike through beautiful landscapes, witness breathtaking scenery, and connect with nature in this historic site dedicated to the Native American experience.

Best time to go to Cape Girardeau

Visitor numbers in Cape Girardeau is generally unchanged in popularity throughout the year. The best time to visit Cape Girardeau is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January34.9°F (1.6°C)Light RainMostly SunnySlightly LowAverage
February38.1°F (3.4°C)Light RainMostly SunnyAverageSlightly High
March48.6°F (9.2°C)Light RainMostly SunnyAverageSlightly High
April57.6°F (14.2°C)Light RainMostly SunnySlightly HighSlightly High
May67.3°F (19.6°C)Light RainMostly SunnyAverageAverage
June76.5°F (24.7°C)Light RainMostly SunnySlightly HighAverage
July79.2°F (26.2°C)Light RainMostly SunnySlightly HighSlightly Low
August77.2°F (25.1°C)Light RainMostly SunnyAverageAverage
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October59.9°F (15.5°C)Light RainMostly SunnySlightly LowAverage
November47.5°F (8.6°C)Light RainMostly SunnyAverageSlightly Low
December40.1°F (4.5°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Cape Girardeau

Traveling to Cape Girardeau, Missouri, you have a few airport options. Paducah, KY (PAH-Barkley Regional) is 45 miles away, with nearby hotels like The Respite Bed and Breakfast, Harrah's Metropolis Hotel & Casino, and The 1857. Marion, IL (MWA-Williamson County Regional) is 41 miles distant, offering accommodations such as Drury Inn & Suites Marion, Holiday Inn Carbondale-Conference Center, and Baymont by Wyndham Marion. The closest option is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), located 6 miles from downtown, where you can find Drury Inn & Suites Cape Girardeau, Drury Plaza Hotel Cape Girardeau Conference Center, and Courtyard by Marriott Cape Girardeau Downtown.

Frequently asked questions

What are the best hotels in Cape Girardeau that travelers recommend?
The Drury Plaza Hotel Cape Girardeau Conference Center stands out as a premier option, boasting an impressive review score of 9.6. Guests rave about its indoor pool, great for families and those seeking relaxation after a day of exploring. The hotel’s attentive staff and comfortable amenities, including premium bedding, ensure a restful stay, making it an ideal choice for both business and leisure travelers.

For those traveling with children, Drury Inn & Suites Cape Girardeau, rated 9.4, is a fantastic family-friendly choice. This hotel features an indoor pool with a pool hoist, prioritizing accessibility while ensuring fun for all ages. Families appreciate the complimentary breakfast and evening snacks, which add convenience to your stay, allowing you to focus on making lasting memories.

Couples seeking a romantic getaway will find The Riverview a great retreat, receiving a great rating of 9.2. With its charming river views and champagne service, this hotel creates a serene atmosphere for relaxation. Guests can unwind in rooms adorned with premium bedding, making it a great spot for a peaceful escape.

For business travelers, the Courtyard by Marriott Cape Girardeau Downtown, also rated 9.6, combines comfort with convenience. Featuring Egyptian cotton sheets and premium bedding, this hotel ensures a restful night’s sleep. Its central location allows easy access to local business hubs, while the inviting lounge areas provide a great setting for informal meetings or networking.
What are the best family hotels in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center stands out as an exceptional family-friendly option, boasting an impressive traveler review rating of 9.6. This hotel features connecting rooms and convenient sofa beds, ensuring ample space for families to relax together. With complimentary cribs for the little ones and a daily housekeeping service, parents can enjoy peace of mind while focusing on family fun. The free breakfast offered on weekdays, complete with a buffet spread, makes mornings easy and stress-free for busy families.

Another excellent choice is the Courtyard by Marriott Cape Girardeau Downtown, also rated 9.6. This hotel offers convenience with kitchenettes available in some rooms, making it easy to prepare snacks or quick meals for your family. The free breakfast caters to younger guests, while the serene garden provides a lovely space for children to play and explore. With cribs and sofa beds available, this hotel is tailored for family comfort.

Lastly, Drury Inn & Suites Cape Girardeau, with an excellent review score of 9.4, offers connecting rooms and sofa beds as well, ensuring families can stay together without feeling cramped. The presence of a kitchen and microwave in the rooms allows for easy meal prep, while the buffet breakfast on weekdays keeps everyone fueled for the day’s adventures. Find more child-friendly accommodations in Cape Girardeau.
What hotels in Cape Girardeau offer free breakfast?
The Drury Plaza Hotel Cape Girardeau Conference Center is an excellent choice for travelers seeking a welcoming and comfortable stay. This hotel boasts a remarkable guest review rating of 9.6, highlighting its emphasis on attentive service and quality. Guests can indulge in a complimentary breakfast buffet each morning, which is superb for fueling up before a day of exploration. Additionally, the indoor pool and hot tub provide a relaxing oasis after a busy day, ensuring both relaxation and fun for families.

For an equally impressive option, the Drury Inn & Suites Cape Girardeau is also a fantastic choice, earning an excellent review score of 9.4. This property offers the same delightful breakfast experience, alongside an indoor pool and hot tub. The added convenience of kitchen facilities makes it particularly family-friendly, allowing for easy meal preparations and snacks for kids. Find more hotels with free breakfast in Cape Girardeau.
What are the best budget hotels in Cape Girardeau?
The Drury Plaza Hotel Cape Girardeau Conference Center stands out as a top budget-friendly option, boasting an impressive traveler review rating of 9.6. This vibrant hotel features an inviting indoor pool and hot tub, superb for families looking to unwind after a day of adventure. Guests appreciate the complimentary breakfast, including a buffet option on weekends, which makes mornings straightforward, especially for those traveling with children. The hotel also provides free WiFi and self-parking, ensuring convenience for all.

Another excellent choice for families is the Hampton Inn Cape Girardeau I 55 East, also rated at 9.6. Families will find ample amenities here, including an indoor pool and a free continental breakfast, which is especially appreciated by busy parents. The hotel’s atmosphere is welcoming, and the availability of cribs and rollaway beds ensures that little ones are well accommodated.

For those seeking a slightly different experience, the Courtyard by Marriott Cape Girardeau Downtown, with the same commendable review score of 9.6, offers a more urban vibe. Ideal for couples or travelers looking for a lively downtown atmosphere, it features a rooftop garden and a kitchenette in select rooms, allowing for a comfortable stay with a touch of independence.

Lastly, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, rated 9.4, combines practicality with modern amenities, making it a great option for those on business trips or families needing extra space. With an indoor pool and convenient access to high-speed internet, this hotel caters to a variety of needs while maintaining a budget-friendly approach. View all budget hotels in Cape Girardeau.
What are the most romantic hotels in Cape Girardeau for couples?
For couples seeking a romantic escape, The Riverview in Cape Girardeau is an excellent choice, boasting an impressive guest review rating of 9.2. This delightful hotel offers stunning river views that enhance the intimate atmosphere, making it great for a getaway with your loved one. See all romantic hotels in Cape Girardeau.
When is the best time to go to Cape Girardeau?
The most popular time to visit Cape Girardeau is in the fall, particularly during October. This month showcases stunning autumn foliage, with temperatures typically ranging from the mid-50s to low 70s Fahrenheit. It’s an ideal time to explore the scenic trails and parks, such as the beautiful Cape Girardeau Conservation Nature Center, where you can immerse yourself in the vibrant colors of fall.

During peak season, which generally spans from May to September, Cape Girardeau experiences a lively atmosphere with many outdoor events and festivals. The summer months are particularly bustling, inviting visitors to partake in riverfront activities, local fairs, and outdoor concerts. However, as the season transitions into October, you’ll find a more relaxed vibe, allowing for leisurely strolls along the Mississippi River or visits to charming local shops.

For those who appreciate a touch of adventure, October is also a fantastic time to enjoy hiking and biking on the numerous trails without the intense heat of summer. The comfortable weather makes it easy to engage in outdoor activities while appreciating the stunning natural landscape.

If you’re looking for a more budget-friendly option, consider visiting in early December. While temperatures dip, the holiday season brings festive charm to the area, and you can enjoy seasonal events and decorations without the crowds.
Where can I find the best nightlife in Cape Girardeau?
Cape Girardeau has a friendly setting with a growing nightlife scene that caters to a variety of tastes.

The downtown area is particularly lively, featuring a mix of bars and restaurants that come alive in the evenings. You can find a range of options, from casual pubs to more upscale dining establishments, many of which offer live music to enhance your night out.

If you’re looking for a relaxed yet vibrant atmosphere, the Riverfront area is great for enjoying picturesque views of the Mississippi River while sipping on cocktails or enjoying local craft beers. This area often hosts events and festivals, providing a great backdrop for a night of fun.

For those who appreciate a more laid-back experience, the neighborhoods surrounding Southeast Missouri State University have a youthful energy, with several bars and eateries that offer a friendly vibe and occasional live performances.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to “My Trips”, and selecting your reservation. To find flexible deals, filter your search by “Fully refundable property” for hotels in Cape Girardeau.
How can I save on a Cape Girardeau hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Cape Girardeau hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It’s free to join, and you’ll unlock our lowest Member Prices as soon as you’re signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Cape Girardeau hotel?
Prices for hotels in Cape Girardeau often vary, but you can find a great deal from $66 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by “Price: low to high” for the cheapest rate.