Top 10 Hotels in Scott City, MO (from $65) 2026 - Competitive Prices

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Scott City

Pet friendly

Apartment

Pool

Cabin

Waterpark

Family friendly

Condo

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Scott City hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

$98 nightly

$111 total

Sep 17 - Sep 18

Total with taxes and fees

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

2. The Riverview

Cape Girardeau

Alyssa

$104 nightly

$117 total

Oct 12 - Oct 13

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

3. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Cheryl

$89 nightly

$101 total

Sep 17 - Sep 18

Total with taxes and fees

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

4. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

$101 nightly

$115 total

Sep 20 - Sep 21

Total with taxes and fees

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

5. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Raidas

$71 nightly

$80 total

Sep 21 - Sep 22

Total with taxes and fees

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel room with a bed, a TV, a desk, and a chair.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

6. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

$88 nightly

$105 total

Oct 4 - Oct 5

Total with taxes and fees

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

7. Drury Inn & Suites Sikeston, MO

Sikeston

Scott Andrew

$102 nightly

$117 total

Sep 17 - Sep 18

Total with taxes and fees

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

$101 nightly

$114 total

Sep 20 - Sep 21

Total with taxes and fees

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

An outdoor patio with tables and chairs, a stone wall, and large windows.

9. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Andrew

$91 nightly

$99 total

Sep 22 - Sep 23

Total with taxes and fees

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

A spacious living room with a sofa set, a coffee table, and a dining area.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

10. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

$125 nightly

$142 total

Sep 27 - Sep 28

Total with taxes and fees

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A hotel room with two beds, a brick wall, and a wooden headboard.

11. Drury Inn & Suites Jackson MO

Jackson

William

$82 nightly

$87 total

Sep 20 - Sep 21

Total with taxes and fees

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

12. Quality Inn Cape Girardeau North

Cape Girardeau

Stephen

$59 nightly

$67 total

Sep 20 - Sep 21

Total with taxes and fees

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

An outdoor patio with stone walls, wicker furniture, and large windows.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

13. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

$106 nightly

$119 total

Sep 20 - Sep 21

Total with taxes and fees

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

14. Hampton Inn Sikeston

Sikeston

Jeffrey

$102 nightly

$115 total

Oct 11 - Oct 12

Total with taxes and fees

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

15. Best Western Plus Sikeston I-55

Sikeston

Bernice

$87 nightly

$99 total

Sep 13 - Sep 14

Total with taxes and fees

A modern retail area with a display of local items and snacks.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

16. Tru By Hilton Cape Girardeau

Cape Girardeau

Darlene

$89 nightly

$102 total

Sep 20 - Sep 21

Total with taxes and fees

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

A bathroom with a marble wall and a white bathtub.

17. Town House Inn Cape Giradreau

Cape Girardeau

Joshua

$78 nightly

$88 total

Sep 24 - Sep 25

Total with taxes and fees

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

18. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

$101 nightly

$114 total

Sep 20 - Sep 21

Total with taxes and fees

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

19. Days Inn and Suites by Wyndham Sikeston

Sikeston

Val

$65 nightly

$75 total

Sep 21 - Sep 22

Total with taxes and fees

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.

A buffet with various food items, including omelets and baked goods, served in metal containers.

20. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

michael

$98 nightly

$111 total

Oct 11 - Oct 12

Total with taxes and fees

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Scott City Hotel Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"We love the room and location"

Drury Inn & Suites Jackson MO

10/10 Excellent

"Excellent all the way around!!"

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"All good, staff friendly and helpful! Breakfast was great and kick back dinner was good!"

The Riverview

10/10 Excellent

"Very clean They need a fitness center !"

Fairfield Inn & Suites by Marriott Cape Girardeau

10/10 Excellent

"The receptionist was very courteous. Helped answer all my questions. We loved the room. And we had a great breakfast before we left."

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"We had no problem checking in. The room was nice and clean. The staff were courteous and helpful. Parking was acceptable. Close to our room. No complaints."

Hampton Inn Sikeston

10/10 Excellent

"Really quiet place close to good restaurants and stores."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"."

Best Western Plus Sikeston I-55

8/10 Good

"Great location, nice, clean and well maintained, Hotel employees were very helpful great customer service,"

More cheap stays in Scott City

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

$57 nightly

$65 total

Sep 20 - Sep 21

Total with taxes and fees

7/10 Good! (673 reviews)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO

$58 nightly

$66 total

Sep 20 - Sep 21

Total with taxes and fees

8.4/10 Very Good! (821 reviews)

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

$65 nightly

$75 total

Sep 21 - Sep 22

Total with taxes and fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

$71 nightly

$80 total

Sep 21 - Sep 22

Total with taxes and fees

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

$87 nightly

$99 total

Sep 13 - Sep 14

Total with taxes and fees

8.4/10 Very Good! (1,001 reviews)

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

$101 nightly

$115 total

Sep 20 - Sep 21

Total with taxes and fees

9.4/10 Exceptional! (1,001 reviews)

Hotels in Scott City with star-rating

Frequently asked questions

What is the best area to stay in Scott City?

The best area to stay in Scott City, Missouri, is near Main Street, especially for those seeking convenience and local flavor.This area is the heart of Scott City, offering a central location for exploring. Main Street itself features a collection of local businesses, including diners and shops that provide a glimpse into the community life. It's a straightforward area, making navigation easy for visitors.For solo travelers or couples looking for a practical and central base, staying near Main Street is ideal.

When is the best time to go to Scott City?

The best time to go to Scott City, Missouri, is during the spring and fall months, specifically from April to May and September to October. These periods offer pleasant weather conditions that are ideal for outdoor activities and exploring the area comfortably.During spring, the temperatures are mild, and the natural scenery comes alive with blooming flowers and lush greenery. This makes it a great time for couples to enjoy scenic walks along the Mississippi River or visit local parks without the discomfort of summer heat or winter cold.Similarly, the fall season in Scott City provides comfortable temperatures and beautiful autumn foliage, which is superb for solo travelers looking for a relaxing getaway.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Scott City.

How much is the nightly rate at a Scott City hotel?

Prices for hotels in Scott City often vary, but you can find a great deal from $65 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Find hotels in Scott City, MO from $65

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Scott City

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Scott City hotels

1. Drury Plaza Hotel Cape Girardeau Conference Center

2. The Riverview

3. Drury Inn & Suites Cape Girardeau

4. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

5. Pear Tree Inn Cape Girardeau West

6. Candlewood Suites Cape Girardeau by IHG

7. Drury Inn & Suites Sikeston, MO

8. Fairfield Inn & Suites by Marriott Cape Girardeau

9. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10. Courtyard by Marriott Cape Girardeau Downtown

11. Drury Inn & Suites Jackson MO

12. Quality Inn Cape Girardeau North

13. Hampton Inn Cape Girardeau I 55 East

14. Hampton Inn Sikeston

15. Best Western Plus Sikeston I-55

16. Tru By Hilton Cape Girardeau

17. Town House Inn Cape Giradreau

18. Fairfield Inn & Suites by Marriott Sikeston

19. Days Inn and Suites by Wyndham Sikeston

20. Holiday Inn Express & Suites Sikeston Southwest by IHG

Top Scott City Hotel Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Jackson MO

Drury Inn & Suites Sikeston, MO

The Riverview

Fairfield Inn & Suites by Marriott Cape Girardeau

Super 8 by Wyndham Sikeston/Miner Area

Hampton Inn Sikeston

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Best Western Plus Sikeston I-55

More cheap stays in Scott City

Super 8 by Wyndham Sikeston/Miner Area

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Days Inn and Suites by Wyndham Sikeston

Pear Tree Inn Cape Girardeau West

Best Western Plus Sikeston I-55

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotels in Scott City with star-rating

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app