La Serena Vacation Rentals

Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for La Serena vacation rentals

A row of single-story houses with a well-maintained lawn and garden beds.

1. Apart Hotel y Cabañas Vegasur

Apart Hotel y Cabañas Vegasur
3.0 star property
La Serena
8.6 out of 10, Excellent, (97 reviews)
"Clean place, friendly staff, beach near, kitchen, and walking distance to nice restaurants and to enjoy the sunset and sunrise. Great location"
United States
Sandra
$46 nightly
The price is $46
Dec 2 - Dec 3
Apart Hotel y Cabañas Vegasur
A modern house with a deck, outdoor seating, and a well-maintained lawn.

2. Cabañas MarSerena

Cabañas MarSerena
3.5 star property
La Serena
9.0 out of 10, Wonderful, (53 reviews)
"very nice place to stay close to the beach, reasonably price and everybody there was very very pleasant"
United States
JOHN
$50 nightly
The price is $50
Nov 23 - Nov 24
Cabañas MarSerena
A cluster of geodesic dome structures with windows, a swimming pool, and outdoor seating.

3. Domos Dream hotel cabañas

Domos Dream hotel cabañas
2.0 star property
La Serena
8.6 out of 10, Excellent, (4 reviews)
"It was far away."
Mexico
Sergio
$70 nightly
The price is $70
Dec 10 - Dec 11
Domos Dream hotel cabañas
A round glass table with a bottle, glasses, and flower petals on a balcony overlooking a beach and cityscape.

4. La Choza VIP Turquesa en La Serena

La Choza VIP Turquesa en La Serena
3.0 star property
Coquimbo
7.8 out of 10, Good, (12 reviews)
"The apartment was very good for my needs and close to the conference centre. Safe, clean, well appointed. Yanitza was a big help and responsive to WhatsApp messages."
Canada
Andrew
$75 nightly
The price is $75
Nov 17 - Nov 18
La Choza VIP Turquesa en La Serena
A room with a large window overlooking a coastal area, a chair, and a small table.

5. Vista al mar - Estudio para 3 personas

Vista al mar - Estudio para 3 personas
2.0 star property
Coquimbo
$44 nightly
The price is $44
Nov 30 - Dec 1
Vista al mar - Estudio para 3 personas
A swimming pool with clear water, surrounded by palm trees and a gazebo.

6. Apart Hotel Gran Pacifico

Apart Hotel Gran Pacifico
3.0 star property
La Serena
8.6 out of 10, Excellent, (39 reviews)
"En gral buena eleccion"
Argentina
Javier
$106 nightly
The price is $106
Dec 6 - Dec 7
Apart Hotel Gran Pacifico
An outdoor seating area with a wooden deck, a cushioned sofa, and potted plants.

7. Cabañas Pinamar

Cabañas Pinamar
3.0 star property
Elqui
$57 nightly
The price is $57
Nov 11 - Nov 12
Cabañas Pinamar
A table with a fruit basket and a plate with cutlery, overlooking a coastal view with buildings and greenery.

8. 2nd Floor WiFi La Serena Beach & Casino!

2nd Floor WiFi La Serena Beach & Casino!
Coquimbo
10.0 out of 10, Exceptional, (1 review)
"Excelente departamento, ubicación y comodidad, muchas gracias Yanitza por todo!!! Esperamos volver pronto!"
United States
Daniela
$132 nightly
The price is $132
Nov 11 - Nov 12
2nd Floor WiFi La Serena Beach & Casino!
Room

9. ELDEPTO LA SERENA

ELDEPTO LA SERENA
3.0 star property
Coquimbo
8.0 out of 10, Very good, (2 reviews)
"Boa localização de fácil acesso, tranquilidade e bom atendimento"
Brazil
Ricardo Horacio
$42 nightly
The price is $42
Nov 16 - Nov 17
ELDEPTO LA SERENA
A spacious room with a dining table, chairs, a hanging light fixture, and a wall adorned with decorative plates.

10. New Listing

New Listing
Coquimbo
$77 nightly
The price is $90
Nov 12 - Nov 13
New Listing
A playground with a slide and climbing structures, a covered seating area, and a view of the sea.

11. Beautiful Apartment on the Beach

Beautiful Apartment on the Beach
Coquimbo
10.0 out of 10, Exceptional, (1 review)
"The property is right on the beach with a huge pool. The parking is gated and secure. There is a walking bridge right beside the building to let you cross the busy highway so you can access restaurants. The host was very accommodating and helpful. The carpets in the hallway were really stained, but that was our only complaint. We had a good stay in a lovely location."
Canada
Layla
$76 nightly
The price is $89
Nov 11 - Nov 12
Beautiful Apartment on the Beach
A balcony with a view of the ocean and buildings.

12. "Nicoland" Playa, piscina, La Serena

"Nicoland" Playa, piscina, La Serena
La Serena
10.0 out of 10, Exceptional, (1 review)
"Hermoso departamento,muy bien amoblado, no le falta nada. Excelente ubicación. Queremos destacar la atención de la anfitriona Yanitza, quien siempre estuvo atenta a todas nuestras necesidades y consultas. De seguro volveremos!"
United States
Daniela
$129 nightly
The price is $129
Nov 11 - Nov 12
"Nicoland" Playa, piscina, La Serena
A residential area with a swimming pool, a well-maintained garden, and tall apartment buildings in the background.

13. Comfortable apartment in Coquimbo with parking

Comfortable apartment in Coquimbo with parking
Coquimbo
$56 nightly
The price is $56
Nov 11 - Nov 12
Comfortable apartment in Coquimbo with parking
A modern lobby with a brick wall, two sofas, wooden furniture, and a view of the outside.

14. Beach, breezes, and the sea—a beautiful and comfortable apartment in an exceptional location.

Beach, breezes, and the sea—a beautiful and comfortable apartment in an exceptional location.
Coquimbo
$82 nightly
The price is $91
Nov 11 - Nov 12
Beach, breezes, and the sea—a beautiful and comfortable apartment in an exceptional location.
A room with a sofa, a small table, a TV mounted on a sliding door, and framed pictures on the wall.

15. Accommodations Near the Ocean, Downtown, and the Valley; Private Room + Free Parking

Accommodations Near the Ocean, Downtown, and the Valley; Private Room + Free Parking
La Serena
$125 nightly
The price is $125
Nov 11 - Nov 12
Accommodations Near the Ocean, Downtown, and the Valley; Private Room + Free Parking
A high-rise residential building with multiple balconies, a parking area, and a view of the sea.

16. Apartment across from La Herradura Beach—ideal for families

Apartment across from La Herradura Beach—ideal for families
Coquimbo
$168 nightly
The price is $168
Nov 11 - Nov 12
Apartment across from La Herradura Beach—ideal for families
A kitchen with a coffee machine, a water dispenser, and a container labeled "Flower Garden" on the counter.

17. Trabajo y Relax VIP en La Serena

Trabajo y Relax VIP en La Serena
La Serena
$80 nightly
The price is $80
Nov 16 - Nov 17
Trabajo y Relax VIP en La Serena
A multi-story residential building with balconies, a gated courtyard, and a street lamp.

18. Apt 107D Jardines del Pacifico IV

Apt 107D Jardines del Pacifico IV
La Serena
$66 nightly
The price is $66
Nov 12 - Nov 13
Apt 107D Jardines del Pacifico IV
A rooftop pool with clear blue water, wooden deck, and lounge chairs.

19. Coquimbo from Above: Ocean View + Panoramic Pool, Self-Check-In 24/7

Coquimbo from Above: Ocean View + Panoramic Pool, Self-Check-In 24/7
Coquimbo
$90 nightly
The price is $90
Nov 11 - Nov 12
Coquimbo from Above: Ocean View + Panoramic Pool, Self-Check-In 24/7
A hotel room with a bed, a nightstand, a lamp, a mirror, and a window with a view of a pool and high-rise buildings.

20. New Listing

New Listing
Coquimbo
$95 nightly
The price is $105
Nov 11 - Nov 12
New Listing
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find vacation rentals that suit your style

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Top La Serena Hotel Reviews

A clear pool surrounded by rocks and vegetation, with a mountain in the background.
REFUGIO EL MOLLE

REFUGIO EL MOLLE

REFUGIO EL MOLLE
Vicuña

10/10 Excellent

Great
United States
America
Reviewed July 25, 2025
REFUGIO EL MOLLE

Find out more about La Serena

Everything you need to know about La Serena vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the La Serena vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Serena vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

La Serena vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in La Serena. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit La Serena in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $42 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on La Serena rentals

At Expedia, we put the best La Serena vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top La Serena rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Serena vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Serena. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find a vacation rental in La Serena?

Yes, we give you a choice of vacation rentals in La Serena near Jardin del Corazon, or you can go with a more remote option if you're looking for a relaxing stay. La Serena is known for its sightseeing tours and spas. Make sure you have time to check out the casinos while you're in the area.

What are some of the best vacation rentals in La Serena?

Lagoon beach marina 312: Visitors like this La Serena vacation home rental. It comes with laundry facilities so you can feel at home during your trip. Some other homes for rent in La Serena include lagoon beach white 803 and Dept. 4th Floor, Pacífico II.

How many vacation rentals will I find in La Serena?

With 48 Expedia vacation rentals, you're sure to find just the right place for your La Serena stay.

What can I see and do in La Serena?

Cultural attractions include Casa Gabriel Gonzalez Videla Historical Museum and Mineralogical Museum, whereas La Serena Beach and Cuatro Esquinas Beach are a couple of picturesque spots to enjoy the outdoors. While here, La Recova Market and Mall Plaza La Serena are other places worth a visit.

What are vacation rentals like in La Serena?

Vacation rentals are private accommodations you can reserve for a short or long stay in La Serena. Vacation rentals provide amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for a family trip.

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