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A cityscape with a prominent courthouse, a mix of historic and modern buildings, and a clear road with vehicles.

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Check prices for these dates, December 15 – 16, 2026

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Our top choices for Lexington guest houses

1. JH Adams Inn, Trademark Collection by Wyndham

A spacious lobby with a checkered floor, leather sofas, and a stone fireplace.

2. Clarion Pointe Winston – Salem Downtown

A modern hotel room with a cityscape view, a sofa, two armchairs, a coffee table, and a desk with a computer.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Learn more about Lexington

Barbecue lovers flock to this 'Barbecue Capital of the World' for smoky pork shoulders and tangy vinegar sauce. Explore the vibrant Main Street district before timing your visit for the annual Barbecue Festival held every October.

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A cityscape with a prominent courthouse, a mix of historic and modern buildings, and a clear road with vehicles.

Frequently Asked Questions

What is the nightly rate for a guest house in Lexington?

Rates for Lexington guest houses vary, but travelers can find great-value prices from $76 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Lexington guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.

What's the difference between a Lexington guest house and a B&B?

A guest house in Lexington is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

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