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Find Hotels near Mayo Clinic Florida in Jacksonville

Stay close to the hospital from $64

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Compare 1658 hotels close to Mayo Clinic Florida with room rates, reviews, and availability. Most hotels are fully refundable.

Margaritaville Jacksonville Beach
2.5 out of 5
2.6 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $179 per night from Feb 5 to Feb 6
$179
per night
Feb 5 - Feb 6
4.4/5 Excellent! (1,331 reviews)
"Beautiful resort, great location on the beach. Parking was a little tough, there is free parking but limited spots... but that's not a slight, even the fact they offered some free parking is a huge PLUS! But amazing staff, from checkin to valet everyone was great. Will be returning for sure"

Reviewed on Jan 31, 2023

Margaritaville Jacksonville Beach
Wyndham Garden Jacksonville
3 out of 5
4.3 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $76 per night from Feb 15 to Feb 16
$76
per night
Feb 15 - Feb 16
3.5/5 Good! (1,456 reviews)
"It was fine for what I paid for it"

Reviewed on Jan 29, 2023

Wyndham Garden Jacksonville
One Ocean Resort and Spa
4.5 out of 5
4.4 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $240 per night from Feb 4 to Feb 5
$240
per night
Feb 4 - Feb 5
4.3/5 Excellent! (1,019 reviews)
"Excellent customer service."

Reviewed on Jan 21, 2023

One Ocean Resort and Spa

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Courtyard by Marriott Jacksonville Beach Oceanfront
3 out of 5
3.1 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $202 per night from Feb 16 to Feb 17
$202
per night
Feb 16 - Feb 17
4.3/5 Excellent! (1,012 reviews)
"Enjoyed the pre check in. Would not hesitate to recommend this hotel"

Reviewed on Jan 30, 2023

Courtyard by Marriott Jacksonville Beach Oceanfront
Hampton Inn Jacksonville Beach/Oceanfront
3 out of 5
3 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $195 per night from Feb 26 to Feb 27
$195
per night
Feb 26 - Feb 27
4.5/5 Wonderful! (1,030 reviews)
"Staff was fantastic. Helped me with everything I needed and were very friendly."

Reviewed on Jan 30, 2023

Hampton Inn Jacksonville Beach/Oceanfront
Sonesta Simply Suites Jacksonville
2.5 out of 5
4.2 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $109 per night from Feb 5 to Feb 6
$109
per night
Feb 5 - Feb 6
4.3/5 Excellent! (1,001 reviews)
Good for our one night
"Just a quick one night getaway. Decent bed and room for the price. The kitchenette sink is rusting in the drain cause a mild funky smell. Not the worst smell but not great either."

Reviewed on Jan 29, 2023

Sonesta Simply Suites Jacksonville
Best Western Premier Jacksonville Hotel
3 out of 5
4.3 mi from Mayo Clinic Florida
The price is $100 per night from Feb 9 to Feb 10
$100
per night
Feb 9 - Feb 10
4/5 Very Good! (1,374 reviews)
Wonderful experience.
"The management staff was very pleasant, respectful, and helpful. I have stayed here before and received the same experience. Always pleasant. The restaurant food was veey good also."

Reviewed on Jan 23, 2023

Best Western Premier Jacksonville Hotel
La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
2.5 out of 5
4.5 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $70 per night from Feb 21 to Feb 22
$70
per night
Feb 21 - Feb 22
3.4/5 (1,043 reviews)
"The room/ hotel was very nice. But the extreme amount of noise in the late/early AM hours made it very difficult to get needed rest."

Reviewed on Jan 30, 2023

La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
The Lodge and Club at Ponte Vedra Beach
5 out of 5
2.3 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $349 per night from Feb 5 to Feb 6
$349
per night
Feb 5 - Feb 6
4.7/5 Exceptional! (615 reviews)
"Perfect"

Reviewed on Jan 25, 2023

The Lodge and Club at Ponte Vedra Beach
SpringHill Suites by Marriott Jacksonville
3 out of 5
3.3 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $124 per night from Feb 5 to Feb 6
$124
per night
Feb 5 - Feb 6
4.2/5 Very Good! (1,027 reviews)
"Hotel was awesome from check in to check out. Everyone was friendly. It was very clean and spacious."

Reviewed on Jan 30, 2023

SpringHill Suites by Marriott Jacksonville
Quality Inn Atlantic Beach - Mayo Clinic Jax Area
2.5 out of 5
6.2 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $89 per night from Feb 5 to Feb 6
$89
per night
Feb 5 - Feb 6
4/5 Very Good! (990 reviews)
Would stay again.
"We were very pleased with our accommodations. The bed was soft yet firm and the pillows were amazing. I loved that they were small and soft and crunchable. There were 4 pillows on the King size bed. Housekeeping was very agreeable when I asked for extra towels and anything else that we needed. Had ..."

Reviewed on Jan 31, 2023

Quality Inn Atlantic Beach - Mayo Clinic Jax Area
Best Western Oceanfront
3 out of 5
2.4 mi from Mayo Clinic Florida
The price is $144 per night from Feb 20 to Feb 21
$144
per night
Feb 20 - Feb 21
4.3/5 Excellent! (1,026 reviews)
"Everything was great"

Reviewed on Jan 27, 2023

Best Western Oceanfront
Holiday Inn Express Jacksonville Beach, an IHG Hotel
2.5 out of 5
2 mi from Mayo Clinic Florida
Fully refundable
The price is $126 per night from Feb 13 to Feb 14
$126
per night
Feb 13 - Feb 14
4.5/5 Wonderful! (1,023 reviews)
Family trip
"The hotel was very clean, room comfortable and close to shopping and restaurants. It was just a few blocks from beach. The staff was extremely pleasant and helpful with any needs. Breakfast was good. Will stay here again!"

Reviewed on Jan 30, 2023

Holiday Inn Express Jacksonville Beach, an IHG Hotel
Ponte Vedra Inn & Club
5 out of 5
2.3 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $439 per night from Feb 4 to Feb 5
$439
per night
Feb 4 - Feb 5
4.7/5 Exceptional! (836 reviews)
"On the beach Great location Room walls a bit thin we could heard the people next door"

Reviewed on Oct 20, 2022

Ponte Vedra Inn & Club
Hyatt Place Jacksonville / St. Johns Town Center
3 out of 5
2.6 mi from Mayo Clinic Florida
Fully refundable
The price is $140 per night from Feb 9 to Feb 10
$140
per night
Feb 9 - Feb 10
4.6/5 Exceptional! (955 reviews)
"Over very good. Lots of shopping and restaurants nearby."

Reviewed on Jan 29, 2023

Hyatt Place Jacksonville / St. Johns Town Center
Marriott Jacksonville
3.5 out of 5
4.3 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $169 per night from Feb 4 to Feb 5
$169
per night
Feb 4 - Feb 5
4.2/5 Excellent! (632 reviews)
"Very nice hotel i was surprised"

Reviewed on Dec 25, 2022

Marriott Jacksonville
Baymont by Wyndham Jacksonville/Butler Blvd
2.5 out of 5
4.5 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $64 per night from Feb 7 to Feb 8
$64
per night
Feb 7 - Feb 8
3.8/5 Good! (1,028 reviews)
"It was nice and clean. Really enjoyed our stay and will be back."

Reviewed on Jan 22, 2023

Baymont by Wyndham Jacksonville/Butler Blvd
Ramada Hotel & Conference Center by Wyndham Jacksonville
3 out of 5
7.4 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $79 per night from Feb 6 to Feb 7
$79
per night
Feb 6 - Feb 7
3.7/5 Good! (1,049 reviews)
"The only issue I had was the air conditioner/heater made quite a bit of noise throughout the stay."

Reviewed on Jan 29, 2023

Ramada Hotel & Conference Center by Wyndham Jacksonville
Fairfield Inn & Suites by Marriott Jacksonville Butler Blvd
2.5 out of 5
4.5 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $119 per night from Feb 5 to Feb 6
$119
per night
Feb 5 - Feb 6
4.3/5 Excellent! (563 reviews)
Good service
"My stay at Fairfield was amazing.. The staff went above and beyond with service.. so five stars from me!!"

Reviewed on Jan 23, 2023

Fairfield Inn & Suites by Marriott Jacksonville Butler Blvd
Red Roof Inn PLUS+ Jacksonville - Southpoint
2.5 out of 5
4.5 mi from Mayo Clinic Florida
Fully refundableReserve now, pay when you stay
The price is $83 per night from Feb 5 to Feb 6
$83
per night
Feb 5 - Feb 6
3.9/5 Good! (974 reviews)
Peace and Quiet
"Very clean room, quiet and peaceful. Definitely would stay here again."

Reviewed on Jan 21, 2023

Red Roof Inn PLUS+ Jacksonville - Southpoint
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Clinic Florida hotels information

Number of reviews
19984
Accommodation
1658 hotels
Lowest Price
$64
Highest Price
$439

Hotels near Other Jacksonville Attractions

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    4.5/5(264 reviews)

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    Jacksonville Beach Pier

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

What top hotels near Mayo Clinic Florida are known for their enhanced cleaning?

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, located steps from Mayo Clinic Florida, is a 3-star hotel offering property cleaning with disinfectant, hand sanitizer for guests, and social distancing measures. If you're looking for a more affordable option, Holiday Inn Express Jacksonville Beach, an IHG Hotel is a 2.5-star hotel within 5 miles and offers enhanced cleaning measures. For other choices, browse all properties near Mayo Clinic Florida with enhanced sanitization practices.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 18 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Wilson Center For the Arts and Players by the Sea. Spend some time exploring the natural beauty of Oceanfront Park, Huguenot Park, and Cradle Creek Preserve. Attractions like Beaches Museum & History Park and Rhoda Martin Cultural Heritage Center highlight the local culture.

Recent reviews of Mayo Clinic Florida hotels
Expedia verified reviews

  • Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

    Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

    5/5 Excellent
    "Great staff and accommodations."
    A verified traveler from Gainesville stayed at Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
    Posted 2 days ago
    Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

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