Medical District Vacations from $398
Book a Hotel + Flight or Car together to unlock savings
Photo by Hector N.
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Medical District Vacation
Our Medical District vacation packages are an easy and handy way to plan and book your next getaway. Discover the true character of this unique neighborhood without the burden of organizing everything yourself. When it's time to sightsee, you'll find plenty of top attractions nearby including Memphis Zoo, Orpheum Theatre and Sun Studio. Visit one, two (or even all!) during your trip to Medical District. Whatever your dream Medical District vacation looks like, you can turn it into reality with Expedia.
The Latest Medical District Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Oliver Hotel, Oxford
Courthouse Square Historic District
Save 100% on your flight
Price was $958, price is now $609 per person
$609
per person
Feb 13 - Feb 16
found 1 day ago
Roundtrip flight included
New York (NYC) to Memphis (MEM)
9.6/10 Exceptional! (306 reviews)
Love the hotel. However, food was subpar.
Reviewed on Nov 8, 2025
River Inn of Harbor Town
Mud Island
Price was $1,494, price is now $1,103 per person
$1,103
per person
Dec 28 - Jan 2
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Memphis (MEM)
9.6/10 Exceptional! (783 reviews)
Very nice clean, quiet property. Breakfast was great.
Reviewed on Oct 18, 2025
Where to stay in Medical District
Find the best Medical District areas and neighborhoods for the activities you enjoy most. Learn more about Medical District
Downtown Memphis
5 out of top 10 points of interest in this area
4/5(1,782 area reviews)
Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.
Medical District Hotel Deals
Motel 6 Memphis, TN - Downtown
210 S Pauline St Memphis TN
Fully refundableReserve now, pay when you stay
$49 nightly
The price is $60 total per night from Nov 30 to Dec 1
$60 total
Nov 30 - Dec 1
Total with taxes and fees
5.4/10 (1,005 reviews)
Yes
Reviewed on Nov 11, 2025
Hu. Hotel
79 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $95 total per night from Dec 9 to Dec 10
$95 total
Dec 9 - Dec 10
Total with taxes and fees
8.4/10 Very Good! (1,569 reviews)
Nice selection
Reviewed on Nov 21, 2025
Big Cypress Lodge
1 Bass Pro Drive Memphis TN
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $270 total per night from Nov 30 to Dec 1
$270 total
Nov 30 - Dec 1
Total with taxes and fees
9/10 Wonderful! (1,698 reviews)
Fun place to stay.
Reviewed on Nov 25, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Medical District
Sun Studio
4.5/5(492 reviews)
Known as The Birthplace of Rock and Roll, this recording studio presents a trip down memory lane with music icons such as Elvis Presley and Johnny Cash.
Hunt-Phelan Home
You can find out about the history of Memphis with a trip to Hunt-Phelan Home. Experience the area's fascinating museums and entertainment choices.
Things to do
Mobsters, Mayhem, & Murder of Memphis Ghost Tour
$32
per adult
Memphis: City Discovery Bus Tour
$38
per adult
98% of travellers recommend
Explore a world of travel with Expedia
- Memphis Hotels
- Hotels near Downtown Memphis
- Cheap Hotels in Memphis
- Hotels near Beale Street
- Hotels near Sun Studio
- Hotels near Mississippi Boulevard Christian Church
- Hotels near Woodruff-Fontaine House
- Hotels near Victorian Village Historic District
- Hotels near Mallory-Neely House
- Hotels near Hunt-Phelan Home
- Hotels near FedEx Forum
- Hotels near New Pathways
- Hotels with an Indoor Pool in Memphis
- Pet-friendly Hotels in Memphis
- Hotels near Elmwood Cemetery
- Hotels near W.C. Handy Memphis Home and Museum
- Hotels near Midtown
- Hotels near AutoZone Park
- Hotels near New Daisy Theater
- 5 Star Hotels in Memphis
- Hotels with Hot Tubs in Memphis
- Cheap Hotels in Downtown Memphis
- Hotels with Suites in Memphis
- Hotels with Free Airport Shuttle in Memphis
- Motels in Memphis
- Casino Hotels in Memphis
- Luxury Hotels in Downtown Memphis
- Hotels near St. Peter Catholic Church
- Hotels near Handy Park
- Hotels near Danny Thomas/ALSAC Pavillion
- Hotels near Peabody Ducks
- Hotels with smoking rooms in Memphis
- Cheap Hotels in Midtown
- Hotels near Minglewood Hall
- Beale Street
- Memphis Vacations
- Mississippi Boulevard Christian Church
- Morris Park
- Victorian Village Historic District Vacations
- Mallory-Neely House
- Hunt-Phelan Home
- Visit Victorian Village Historic District
- Peabody Ducks
- First Baptist Beale Street Church
- Gibson Guitar Museum
- W.C. Handy Memphis Home and Museum
- New Daisy Theater
- Withers Collection Museum and Gallery
- AutoZone Park
- FedEx Forum
- Memphis Rock 'n' Soul Museum
- St. Peter Catholic Church
- Handy Park
- Memphis Music Hall of Fame
- Minglewood Hall
- St. Mary's Catholic Church
- Court Square
- Downtown Memphis Vacations
- Fire Museum of Memphis
- Bass Pro Shops at the Pyramid
- Belz Museum of Asian and Judaic Art
- Statue of Elvis
- The Cotton Museum at the Memphis Cotton Exchange
- Center for Southern Folklore
- Mason Temple
- Orpheum Theatre
- Cotton Exchange Building
- Visit Downtown Memphis
- Mississippi River Museum at Mud Island
- Renasant Convention Center
- Cannon Center for Performing Arts
- Mississippi River Park
- Tennessee State Welcome Center
- Beale Street Landing
- Visit Memphis
- Stax Museum of American Soul Music
- Where to stay in Memphis
- Mud Island River Park
- Visit Midtown
- Car rentals near Memphis
- Car rentals near Mississippi Boulevard Christian Church
- Car rentals near Victorian Village Historic District
- Car rentals near Mallory-Neely House
- Car rentals near FedEx Forum
- Compact Car Rentals near FedEx Forum
- SUV Car Rentals near FedEx Forum
- Sportscar Car Rentals near FedEx Forum
- Van Car Rentals near FedEx Forum
- Luxury Car Rentals near FedEx Forum
- Fullsize Car Rentals near FedEx Forum
- Mini Car Rentals near FedEx Forum
- Standard Car Rentals near FedEx Forum
- Car rentals near AutoZone Park
- Premium Car Rentals near AutoZone Park
- Enterprise Rental Cars in Memphis
- Van Car Rentals in Memphis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.