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Find hotels in Morehouse, MO from $57

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Check prices for these dates, December 14 – 15, 2026

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Our top choices for Morehouse hotels

1. Holiday Inn Express & Suites Sikeston Southwest by IHG

A buffet with labeled containers of turkey sausage and cookies.

Location: Sikeston
Guest rating: 8.8/10 (Excellent, 527 reviews)
Price: $95 nightly, $108 total, Dec 13 - Dec 14, Total with taxes and fees
Review: Location was perfect, by George

2. Hampton Inn Sikeston

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

Location: Sikeston
Guest rating: 9/10 (Wonderful, 659 reviews)
Price: $101 nightly, $115 total, Nov 22 - Nov 23, Total with taxes and fees
Review: Quick overnight but great stay, by Conner

3. Fairfield Inn & Suites by Marriott Sikeston

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

Location: Sikeston
Guest rating: 9.4/10 (Exceptional, 118 reviews)
Price: $110 nightly, $125 total, Nov 21 - Nov 22, Total with taxes and fees
Review: Friendly staff, great breakfast, nice amenities, by Roslyn

4. Drury Inn & Suites Sikeston, MO

A Drury Inn & Suites building with a covered entrance, multiple windows, and a parking lot.

Location: Sikeston
Guest rating: 9.6/10 (Exceptional, 1002 reviews)
Price: $94 nightly, $108 total, Nov 22 - Nov 23, Total with taxes and fees
Review: Great place to stay!, by Tiffany

5. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

Location: Sikeston
Guest rating: 8.4/10 (Very good, 831 reviews)
Price: $63 nightly, $72 total, Nov 15 - Nov 16, Total with taxes and fees
Review: Very clean property and the staff were very accommodating., by Craig

6. TownePlace Suites by Marriott Sikeston

Location: Sikeston
Guest rating: 9.2/10 (Wonderful, 33 reviews)
Price: $109 nightly, $124 total, Nov 22 - Nov 23, Total with taxes and fees
Review: I liked the lobby, bar and breakfast areas. The full breakfast buffet was awesome. Super nice room with kitchenette. Staff were great., by Mark

7. Best Western Plus Sikeston I-55

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

Location: Sikeston
Guest rating: 8.4/10 (Very good, 1000 reviews)
Price: $70 nightly, $80 total, Dec 14 - Dec 15, Total with taxes and fees
Review: Clean rooms, great parking, very nice staff, by Shelley

8. Days Inn and Suites by Wyndham Sikeston

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

Location: Sikeston
Guest rating: 7.4/10 (Good, 1001 reviews)
Price: $66 nightly, $76 total, Nov 17 - Nov 18, Total with taxes and fees
Review: It was clean, the room was nice and roomy, bed was very comfortable. Some things were in need of minor repairs, but nothing major., by Earl

9. Super 8 by Wyndham Sikeston/Miner Area

A hotel room with a TV, microwave, desk, chair, two beds, and a window with curtains.

Location: Sikeston
Guest rating: 7/10 (Good, 696 reviews)
Price: $58 nightly, $66 total, Nov 22 - Nov 23, Total with taxes and fees
Review: It is a clean place, and we enjoyed our stay, by Laura

10. Comfort Inn & Suites Sikeston I-55

A modern building with a flat roof and large windows.

Location: Sikeston
Guest rating: 8.4/10 (Very good, 322 reviews)
Price: $84 nightly, $96 total, Nov 22 - Nov 23, Total with taxes and fees
Review: The room was nice, by Fred

11. Country Yard Inn and Suite

A hotel room with a bed, bedside table, desk, chair, telephone, television, and a bathroom with a mirror and sink.

Location: Sikeston
Guest rating: 6.8/10 (164 reviews)
Price: $55 nightly, $63 total, Nov 15 - Nov 16, Total with taxes and fees
Review: It was an ok room for the price paid., by Marianne

12. Econo Lodge Dexter

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

Location: Dexter
Guest rating: 6.8/10 (290 reviews)
Price: $51 nightly, $58 total, Dec 14 - Dec 15, Total with taxes and fees
Review: It was nice for an overnight stay. Didn’t use to much it was mainly sleeping quarters for me., by DeMarco

13. Hampton Inn By Hilton Dexter

A Hampton Inn hotel with a modern design, featuring a flat roof and a prominent signage.

Location: Dexter
Guest rating: 9.6/10 (Exceptional, 85 reviews)
Price: $98 nightly, $111 total, Nov 22 - Nov 23, Total with taxes and fees
Review: This place is Brand new and really great!, by Bryan

14. The Riverstone Hotel Charleston-Sikeston

A building with a fountain and flower beds in front.

Location: Charleston
Guest rating: 6.8/10 (443 reviews)
Price: $66 nightly, $74 total, Nov 17 - Nov 18, Total with taxes and fees
Review: Everything was great clean helpful Everything friendly., by Kathleen

15. Travelodge by Wyndham Dexter

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

Location: Dexter
Guest rating: 7.6/10 (Good, 425 reviews)
Price: $86 nightly, $98 total, Nov 22 - Nov 23, Total with taxes and fees
Review: Staff was very friendly, by Steven

16. Dexter Inn

A restaurant with a counter, seating area, and a television.

Location: Dexter
Guest rating: 7/10 (Good, 373 reviews)
Price: $69 nightly, $78 total, Nov 17 - Nov 18, Total with taxes and fees
Review: breakfast was good, staff friendly, pool area needs work, by Edward

17. OYO Hickory House Inn

A hotel room with a bed, a desk, a chair, a television, and a small refrigerator.

Location: Dexter
Guest rating: 5.6/10 (147 reviews)
Price: $64 nightly, $72 total, Nov 15 - Nov 16, Total with taxes and fees
Review: Great staff! Clean rooms and convinient, by DIEGO

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Morehouse Hotel Reviews

Drury Inn & Suites Sikeston, MO

Address: 2608 East Malone Ave, Miner, Sikeston, MO, 63801, US
Location: Sikeston
Star rating: 3/5
Guest rating: 9.6/10 (1002 reviews)
Review: Food was very good both supper and breakfast. Our room rate was high compared to a couple just checking in before us WHY!! We booked room in September, by Judy, January 31, 2025, rated 10/10 Excellent

Hampton Inn Sikeston

Address: 1240 Commerce Drive, Sikeston, MO, 63801, US
Location: Sikeston
Star rating: 2.5/5
Guest rating: 9/10 (659 reviews)
Review: Staff was really nice, by Stacey, April 10, 2025, rated 10/10 Excellent

Holiday Inn Express & Suites Sikeston Southwest by IHG

Address: 115 Hospitality Dr, Sikeston, MO, 63801, US
Location: Sikeston
Star rating: 2.5/5
Guest rating: 8.8/10 (527 reviews)
Review: Everything was Great!😊, by Anonymous traveler, April 25, 2021, rated 10/10 Excellent

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Address: 100 Matthews Lane, Sikeston, MO, 63801, US
Location: Sikeston
Star rating: 2.5/5
Guest rating: 8.4/10 (831 reviews)
Review: Professional courteous staff, clean, friendly. Nice amount of room-in room!, by Anonymous traveler, August 30, 2018, rated 10/10 Excellent

Comfort Inn & Suites Sikeston I-55

Address: 109 Matthews Ln, Sikeston, MO, 63801, US
Location: Sikeston
Star rating: 2.5/5
Guest rating: 8.4/10 (322 reviews)
Review: This is a fantastic hotel! The staff is very wonderful and helpful and thoughtful when my father passed away in November of 2017, part of my family stayed at this hotel. Now I am back here waiting for my mother to arrive for we are going to finally get to see my father who was a Vietnam veteran and was buried at the Bloomfield Cemetery has his headstone put up anyhow I have had some difficulties with a lot of the hotels around here in this one is by far the best I would recommend it to anyone., by Anonymous traveler, June 2, 2018, rated 10/10 Excellent

Days Inn and Suites by Wyndham Sikeston

Address: 220 S Interstate Dr, Sikeston, MO, 63801, US
Location: Sikeston
Star rating: 2/5
Guest rating: 7.4/10 (1001 reviews)
Review: ., by Jennifer, October 3, 2023, rated 10/10 Excellent

Dexter Inn

Address: 1807 W Business US Highway 60, Dexter, MO, 63841, US
Location: Dexter
Star rating: 2.5/5
Guest rating: 7/10 (373 reviews)
Review: Clean room clean bathroom and nice staff, by david, August 9, 2026, rated 10/10 Excellent

Frequently Asked Questions

What are some of the best vacation home rentals in Morehouse?

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This vacation home rental near Morehouse offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. See all vacation rentals in Morehouse.

If I need to cancel my hotel reservation in Morehouse, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Morehouse.

Where can I learn more about changing or cancelling my trip to Morehouse?

For additional details about changing or cancelling your trip to Morehouse, head over to our customer service page.

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