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Recommended hotels in Sikeston

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1007)
"Great place and staff, very accommodating!"
United States
Megan
$90 nightly
The price is $102
Dec 28 - Dec 29
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1008)
"Clean room, great location and friendly staff"
United States
Mark
$90 nightly
The price is $103
Dec 26 - Dec 27
Total with taxes and fees
Drury Inn & Suites Sikeston, MO

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1006)
"Great stay, everything was clean and comfortable. "
United States
Charles
$74 nightly
The price is $84
Dec 24 - Dec 25
Total with taxes and fees
Best Western Plus Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (673)
"Great place "
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GUY
$84 nightly
The price is $91
Jan 7 - Jan 8, 2026
Total with taxes and fees
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Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
$70 nightly
The price is $79
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (720)
"Stayed one night. Good rate for the Hotel "
United States
Paul
$55 nightly
The price is $63
Dec 23 - Dec 24
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (475)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
$107 nightly
The price is $121
Dec 23 - Dec 24
Total with taxes and fees
The Riverview

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
$91 nightly
The price is $103
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (449)
"Friendly staff clean rooms "
United States
Christopher
$98 nightly
The price is $110
Dec 28 - Dec 29
Total with taxes and fees
Hampton Inn Sikeston

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
United States
Ray
$90 nightly
The price is $102
Dec 26 - Dec 27
Total with taxes and fees
Drury Inn & Suites Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (142)
"Nice hotel, clean and comfortable "
United States
Laura
$88 nightly
The price is $99
Jan 1 - Jan 2, 2026
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1007)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
$83 nightly
The price is $88
Dec 23 - Dec 24
Total with taxes and fees
Drury Inn & Suites Jackson MO

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
$116 nightly
The price is $131
Jan 1 - Jan 2, 2026
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1002)
"Everything was clean, staff was friendly "
United States
Matthew
$75 nightly
The price is $86
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn Sikeston

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
"Great stay"
United States
Heather
$70 nightly
The price is $79
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn Cape Girardeau West

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (387)
"Very nice"
United States
Dennis
$76 nightly
The price is $85
Dec 25 - Dec 26
Total with taxes and fees
Travelodge by Wyndham Dexter

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (884)
"Room was clean and spacious."
United States
George
$77 nightly
The price is $92
Jan 19 - Jan 20, 2026
Total with taxes and fees
Candlewood Suites Cape Girardeau by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
$93 nightly
The price is $105
Jan 11 - Jan 12, 2026
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
"Excellent stay"
United States
Christina
$102 nightly
The price is $115
Dec 28 - Dec 29
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (3)
"Staff was helpful and professional. The rooms were clean and comfortable "
United States
Michael
$105 nightly
The price is $118
Dec 28 - Dec 29
Total with taxes and fees
Hampton Inn By Hilton Dexter
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Top Sikeston Hotel Reviews

Find out more about Sikeston

Sikeston B&B information

Number of reviews
14,428
Accommodation
5 B&B
Lowest Price
$63
Highest Price
$131

Frequently asked questions

What is the nightly rate for a Bed and Breakfast in Sikeston?
Prices for B&Bs in Sikeston often vary, but you can find a great deal from $63 with Expedia. All sorts of factors affect price, such as location and the time of year. It usually costs more to stay at Sikeston B&Bs over the weekend too. Travelers can find the best deals by being flexible with their dates, and by using our filters to sort prices from low to high.
When is the best time to book a B&B in Sikeston?
The best time to book a B&B in Sikeston is during the vibrant spring months from March to May. This period brings pleasant temperatures, typically ranging from the low 40s to mid-70s Fahrenheit, creating an inclusive setting for outdoor exploration and local events. As the flowers bloom and the landscape comes alive, visitors can enjoy a variety of activities, including scenic walks along the nearby trails and visits to local attractions like the Sikeston Depot Museum.

April, in particular, is a delightful month to visit, offering a wonderful balance of comfortable weather and lively community events. With many festivals and outdoor gatherings taking place, it's an excellent opportunity to immerse yourself in the local culture while enjoying the pleasant spring climate.

For those seeking a more budget-friendly experience, consider traveling to Sikeston in November. While this month is quieter, it still offers charming sights and experiences, such as exploring the area's unique cuisine, including the famous Sikeston BBQ.
What is the difference between a Sikeston Bed & Breakfast and a hotel?
Every Sikeston B&B has its own unique feel. Whether it's a cozy reading space or a sunlit breakfast nook to enjoy your morning cup of coffee, the quaint details are what make bed and breakfasts a home away from home. Travelers can look forward to personal touches, thoughtful amenities and of course a scrumptious breakfast at Sikeston B&Bs.

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