Photo by Jessica King

Find pet friendly hotels in Sikeston, MO from $54

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Most hotels are fully refundable. Because flexibility matters.

Top Sikeston Pet-friendly Hotels

Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is $117 per night from Oct 3 to Oct 3
4.8/5Exceptional! (630 reviews)
"Wonderful breakfast!"

Reviewed on Jul 26, 2021

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Jackson MO
3 out of 5
225 Drury Lane, Jackson, MO
Fully refundableReserve now, pay when you stay
The price is $85 per night from Oct 3 to Oct 3
4.7/5Exceptional! (655 reviews)
"The staff was superb. The food was delicious. The property was very clean. We sat near the dining area and chatted several hours. They mopped twice during that time."

Reviewed on Aug 2, 2021

Drury Inn & Suites Jackson MO
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is $108 per night from Oct 4 to Oct 4
4.6/5Exceptional! (514 reviews)
"Every staff member at the hotel was friendly and helpful. Free breakfast was delicious along with the evening happy hour. Clean as well!"

Reviewed on Sep 23, 2021

Drury Inn & Suites Cape Girardeau
You could be seeing lower prices

You could be seeing lower prices

With member prices, you could save 10% or more right now on thousands of properties.
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is $117 per night from Oct 3 to Oct 3
4.6/5Exceptional! (902 reviews)
"This is now my favorite hotel. Like literally I’m looking for Drury Inns when planning any trip. The hotel staff was awesome, pool was real nice, breakfast was terrific, but then the side perks: Free Dinner and alcohol! I mean granted it was chicken nuggets, hot dogs, and the like, but I got kids ..."

Reviewed on Sep 5, 2021

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is $99 per night from Oct 10 to Oct 10
4.5/5Wonderful! (978 reviews)
"The facility is well kept and the staff is very friendly."

Reviewed on Sep 12, 2021

Pear Tree Inn Sikeston
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is $84 per night from Sep 27 to Sep 27
4.3/5Excellent! (961 reviews)
"They had a hot breakfast. The room was clean; the staff friendly when I asked for more towels and they had cookies and milk in the afternoon!"

Reviewed on Aug 27, 2021

Auburn Place Hotel And Suites
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is $67 per night from Oct 24 to Oct 24
4.3/5Excellent! (984 reviews)
"Clean. Great employees Best stay we have had in a long time. Would definitely recommend."

Reviewed on Aug 12, 2021

Pear Tree Inn Cape Girardeau Near the Medical Center
Comfort Suites Jackson-Cape Girardeau
2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
Fully refundableReserve now, pay when you stay
The price is $87 per night from Sep 27 to Sep 27
4.2/5Excellent! (484 reviews)
"Very friendly staff and clean room. It was very quiet."

Reviewed on Aug 28, 2021

Comfort Suites Jackson-Cape Girardeau
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is $85 per night from Oct 22 to Oct 22
4.2/5Excellent! (732 reviews)
"Customer service"

Reviewed on Aug 17, 2021

Best Western Plus Sikeston
Comfort Inn & Suites Sikeston I-55
2.5 out of 5
109 Matthews Ln, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is $92 per night from Oct 3 to Oct 3
4.1/5Very Good! (89 reviews)
Good night’s rest
"The room was comfortable but the TV could have been bigger."

Reviewed on Jun 14, 2021

Comfort Inn & Suites Sikeston I-55
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
Fully refundable
The price is $97 per night from Oct 3 to Oct 3
4.1/5Very Good! (376 reviews)
"Friendly, efficient staff. If anything was needed they were quick to respond. Will definitely stay here again."

Reviewed on Sep 6, 2021

Candlewood Suites Cape Girardeau, an IHG Hotel
Travel Inn & Suites
2.5 out of 5
100 Matthews Lane, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is $55 per night from Oct 4 to Oct 4
3.9/5Very Good! (162 reviews)
"When we first walked in, the air was fresh and clean. The gentleman behind the counter was polite and efficient. Our room was clean and very well set up. No coffee or hair dryer, but with covid, that is acceptable. We travel this route often, and will stop here again."

Reviewed on Sep 19, 2021

Travel Inn & Suites
Travelodge by Wyndham Dexter
2 out of 5
1608 W Business US Highway 60, Dexter, MO
Fully refundableReserve now, pay when you stay
The price is $84 per night from Oct 2 to Oct 2
3.7/5Good! (256 reviews)
"Better than the last time we stayed"

Reviewed on Sep 26, 2021

Travelodge by Wyndham Dexter
Quality Inn Charleston I-57
2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
Fully refundableReserve now, pay when you stay
The price is $60 per night from Oct 13 to Oct 13
3.6/5Good! (216 reviews)
"Convenient"

Reviewed on Aug 21, 2021

Quality Inn Charleston I-57
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is $73 per night from Sep 27 to Sep 27
3.5/5Good! (670 reviews)
"The staff were friendly and helpful. The room was clean but devoid of any extras. There were few towels, cups, no extra blanket, no TV guide or literature on the area, activities, etc. There was not a coffee pot in the room. They advertise free breakfast but did not have it. It was okay for one night ..."

Reviewed on Sep 17, 2021

Days Inn and Suites by Wyndham Sikeston
Eagle Inn Charleston
2 out of 5
2811 East Marshall Street, Charleston, MO
Fully refundableReserve now, pay when you stay
The price is $66 per night from Sep 27 to Sep 27
3.4/5 (78 reviews)
"With booking this room I saved money. Room was very clean an peaceful site. Sleep like a baby."

Reviewed on Apr 11, 2021

Eagle Inn Charleston
Dexter Inn
2.5 out of 5
1807 W Business US Highway 60, Dexter, MO
Fully refundableReserve now, pay when you stay
The price is $65 per night from Sep 28 to Sep 28
3.3/5 (128 reviews)
"The room had a back door."

Reviewed on Sep 9, 2021

Dexter Inn
Econo Lodge Dexter
2 out of 5
913 Outer Rd, Dexter, MO
Fully refundableReserve now, pay when you stay
The price is $60 per night from Sep 27 to Sep 27
3.3/5 (104 reviews)
"Very nice clean facility."

Reviewed on Jul 16, 2021

Econo Lodge Dexter
Super 8 by Wyndham Sikeston/Miner Area
2 out of 5
2609 E Malone Ave, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is $54 per night from Oct 17 to Oct 17
3.1/5 (413 reviews)
"Great staff, clean room and facility"

Reviewed on Sep 1, 2021

Super 8 by Wyndham Sikeston/Miner Area
Country Yard Inn and Suite
2 out of 5
110 S Interstate Dr, Sikeston, MO
3.1/5 (191 reviews)
"Stay there was ok. They need some upkeep on the building itself. All door handles loose and bathroom floor was dirty. New plumbing needed."

Reviewed on Jan 17, 2021

Get rates
Country Yard Inn and Suite
Don't see what you're looking for?
We've got more Pet-friendly Hotels. Find the right one for you.
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

More trip options