Find hotels near National Great Rivers Museum, Alton from $66

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Our top choices for National Great Rivers Museum hotels

Free daily buffet breakfast
Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG
2.5 star property
3.2 mi from National Great Rivers Museum
9.2 out of 10, Wonderful, (163)
"Staff and location were perfect"
United States
Ileta
$118 nightly
The price is $135
Jan 1 - Jan 2, 2026
Total with taxes and fees
Holiday Inn Express and Suites Alton St Louis Area by IHG
Exterior
Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
2.5 star property
3.4 mi from National Great Rivers Museum
9.0 out of 10, Wonderful, (644)
"The staff were very professional and friendly. The breakfast had a great selection."
United States
Melissa
$114 nightly
The price is $130
Jan 11 - Jan 12, 2026
Total with taxes and fees
Hampton Inn & Suites St. Louis/Alton
Lobby lounge
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
2.5 star property
9.3 mi from National Great Rivers Museum
9.2 out of 10, Wonderful, (488)
"This hotel was well kept,the breakfast was excellent. Stsff was friendly. "
United States
Dennis M
$112 nightly
The price is $124
Jan 11 - Jan 12, 2026
Total with taxes and fees
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Exterior
Bel Air Motel

Bel Air Motel

Bel Air Motel
3.5 star property
2.5 mi from National Great Rivers Museum
8.6 out of 10, Excellent, (196)
"Great place super clean. Only thing missing no coffee and our room could have had a nice bistro table to sit at"
United States
James
$87 nightly
The price is $97
Dec 31 - Jan 1, 2026
Total with taxes and fees
Bel Air Motel
Exterior
Best Western Plus Parkway Hotel

Best Western Plus Parkway Hotel

Best Western Plus Parkway Hotel
2.5 star property
3.3 mi from National Great Rivers Museum
8.2 out of 10, Very Good, (1002)
"Staff was excellent when checking in"
United States
larry
$77 nightly
The price is $87
Jan 11 - Jan 12, 2026
Total with taxes and fees
Best Western Plus Parkway Hotel
Gazebo
Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
10.8 mi from National Great Rivers Museum
8.6 out of 10, Excellent, (650)
"The room was very clean and the staff is always friendly "
United States
Lynn
$91 nightly
The price is $105
Jan 1 - Jan 2, 2026
Total with taxes and fees
Country Hearth Inn & Suites Edwardsville St. Louis
Lobby
The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel
3.0 star property
2.4 mi from National Great Rivers Museum
7.8 out of 10, Good, (762)
"The hotel is being remodeled, so it's hard to give it a fair review."
United States
Stephen
$84 nightly
The price is $96
Jan 25 - Jan 26, 2026
Total with taxes and fees
The Great Rivers, an Ascend Collection Hotel
Lobby
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
10.8 mi from National Great Rivers Museum
8.4 out of 10, Very Good, (810)
"Great staff, breakfast was excellent and rooms were clean"
United States
Carlos
$102 nightly
The price is $117
Jan 18 - Jan 19, 2026
Total with taxes and fees
Comfort Inn Edwardsville - St. Louis
Blackout drapes, free WiFi, bed sheets
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
8.9 mi from National Great Rivers Museum
7.8 out of 10, Good, (583)
"Yes, very good, yes good breakfast, yes truck parking."
United States
mark
$60 nightly
The price is $66
Dec 31 - Jan 1, 2026
Total with taxes and fees
Red Lion Inn & Suites Pontoon Beach
Free daily self-serve breakfast
La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
3.0 star property
9.7 mi from National Great Rivers Museum
7.6 out of 10, Good, (514)
"The hotel staff was exceptionally accommodating. Would stay here over anywhere in the area. "
United States
Kari
$99 nightly
The price is $114
Dec 31 - Jan 1, 2026
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Pontoon Beach
Free daily buffet breakfast
Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
10.8 mi from National Great Rivers Museum
9.2 out of 10, Wonderful, (823)
"Always a good stay here!"
United States
Chelsie
$116 nightly
The price is $133
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express & Suites Edwardsville by IHG
Desk, iron/ironing board, free WiFi, bed sheets
Super 8 by Wyndham Alton

Super 8 by Wyndham Alton

Super 8 by Wyndham Alton
2.0 star property
3.3 mi from National Great Rivers Museum
7.0 out of 10, Good, (872)
"The place was clean and plenty of room for our boat"
United States
David
$90 nightly
The price is $103
Dec 31 - Jan 1, 2026
Total with taxes and fees
Super 8 by Wyndham Alton
Breakfast area
Quality Inn Florissant - St Louis

Quality Inn Florissant - St Louis

Quality Inn Florissant - St Louis
2.5 star property
12 mi from National Great Rivers Museum
7.6 out of 10, Good, (1000)
"Hotel very old, not taken care of. Poor breakfast, OJ was rotten in the dispenser. Do not recommend "
United States
Thomas
$68 nightly
The price is $79
Jan 5 - Jan 6, 2026
Total with taxes and fees
Quality Inn Florissant - St Louis
Reception
Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville
2.5 star property
11.4 mi from National Great Rivers Museum
7.4 out of 10, Good, (72)
"We enjoyed our stay"
United States
Susan
$106 nightly
The price is $118
Jan 5 - Jan 6, 2026
Total with taxes and fees
Hampton Inn & Suites St. Louis-Edwardsville
Lobby sitting area
Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach
3.0 star property
9.6 mi from National Great Rivers Museum
8.6 out of 10, Excellent, (806)
"Staff and very nice, good breakfast, soft bed…. I would definitely stay again "
United States
LaSonya
$85 nightly
The price is $95
Jan 4 - Jan 5, 2026
Total with taxes and fees
Best Western Plus Pontoon Beach
Exterior
Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area
2.0 star property
7.7 mi from National Great Rivers Museum
6.4 out of 10, (15)
"Its nice here"
United States
Sheila
$67 nightly
The price is $73
Jan 7 - Jan 8, 2026
Total with taxes and fees
Budget Motel Granite City/St Louis Area
Premium bedding, pillowtop beds, blackout drapes, iron/ironing board
Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis
2.0 star property
7.7 mi from National Great Rivers Museum
6.2 out of 10, (246)
"Overall the stay was adequate, right off the highway so convenient."
United States
Henry
$68 nightly
The price is $79
Jan 5 - Jan 6, 2026
Total with taxes and fees
Econo Lodge Inn & Suites Granite City - St. Louis
Lobby
Comfort Inn Alton near I-255

Comfort Inn Alton near I-255

Comfort Inn Alton near I-255
2.5 star property
2.4 mi from National Great Rivers Museum
7.6 out of 10, Good, (507)
"Perfect accommodations for a brief overnight stay. "
United States
Steffany
$80 nightly
The price is $91
Jan 11 - Jan 12, 2026
Total with taxes and fees
Comfort Inn Alton near I-255
Lobby
Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach
2.0 star property
9.5 mi from National Great Rivers Museum
6.2 out of 10, (571)
"Bed was soooooooo comfortable and front desk guy that checked me in was great as well "
United States
Maurice
$65 nightly
The price is $72
Jan 11 - Jan 12, 2026
Total with taxes and fees
Days Inn by Wyndham Pontoon Beach
House (2 Bedrooms) | Interior
12 Mi to St Louis: Pet-friendly Metro East Home

12 Mi to St Louis: Pet-friendly Metro East Home

12 Mi to St Louis: Pet-friendly Metro East Home
3.0 star property
10 mi from National Great Rivers Museum
$193 nightly
The price is $211
Jan 3 - Jan 4, 2026
Total with taxes and fees
12 Mi to St Louis: Pet-friendly Metro East Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top National Great Rivers Museum Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"It was nice clean and the front desk help were very professional. "
Peter 1-night trip
Posted 3 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hotels near other National Great Rivers Museum attractions

Ellis Island

Commune with nature and explore the great outdoors at Ellis Island during your travels in West Alton. While you're in the area, wander around the parks.
See properties

Fast Eddie's Bon Air

4.7/5 (3 reviews)
You can do some window-shopping at Fast Eddie's Bon Air during your trip to Alton. Visit the shops in this family-friendly area, or simply enjoy its restaurants.
See properties

Frequently asked questions

What's the area like around National Great Rivers Museum?
National Great Rivers Museum is located in an area of Alton that travelers like for its university setting. You'll find 24 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to National Great Rivers Museum?
Best Western Plus Pontoon Beach is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. You'll find it 9.6 mi (15.5 km) from National Great Rivers Museum. Other good choices around the area include Hyatt Regency St. Louis at The Arch and Renaissance St. Louis Airport Hotel.
How many hotels will I be able to find close to National Great Rivers Museum?
Expedia has 24 hotels and other accommodations a few miles from National Great Rivers Museum.
If I need to cancel the hotel reservation for my stay near National Great Rivers Museum, will I receive a refund?
Yes, most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get top deals close to National Great Rivers Museum.
Where can I learn more about changing or cancelling my trip in the area near National Great Rivers Museum?
For more information about changing or cancelling your stay near National Great Rivers Museum, head over to our customer service page.
What can I see and do near National Great Rivers Museum?
You'll want to browse the exhibits at Historic Museum of Torture Devices and Alton Prison. You can enjoy nature at Ellis Island, Jones-Confluence Point State Park, or Columbia Bottom Conservation Area. Looking for a little shopping break? A trip to Fast Eddie's Bon Air, Alton Square Mall, and Mineral Springs Mall might be just the ticket while you're in the area around National Great Rivers Museum.

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